Franziska Knolle
@franziskaknolle.bsky.social
220 followers 270 following 33 posts
Cognitive, clinical, computational neuroscience: I study how we understand language and make decisions, and what happens in the brain if things go wrong. https://franziskaknolle.com https://www.tum.de https://www.mri.tum.de
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franziskaknolle.bsky.social
I am very excited to share our new preprint together with @Isabella Goodwin, @Kelly Diederen, @Emily Hird,
@veithweilnhammer.bsky.social, and @Marta Garrido! Where does predictive processing stand in psychosis research - revisiting Sterzer et al (2018) seven years later. 🧠🔍?
osf.io/preprints/ps...
Reposted by Franziska Knolle
drrickadams.bsky.social
Post doc job alert 📢! Announcing a v exciting job on a Wellcome-funded project in my group at UCL, looking at auditory hallucinations... Advert here 👀: rb.gy/230w8l - deadline is end of Oct. Please apply! 1/5
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
rb.gy
Reposted by Franziska Knolle
dcameron.bsky.social
Compassion in Philadelphia
Reposted by Franziska Knolle
kojamf.bsky.social
Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.
Reposted by Franziska Knolle
profsimonfisher.bsky.social
Twenty-four years ago today, our paper “A forkhead-domain gene is mutated in a severe speech and language disorder” was published: www.nature.com/articles/350....
A personal thread about the ups & downs of the journey we took to get to that point....1/n
🗣️🧬🧪
Image shows the first two printed pages of the paper “A forkhead-domain gene is mutated in a severe speech and language disorder” by Cecilia Lai and colleagues, published in Nature in 2001 (volume 413, pages 519-523). The abstract reads as follows:
Individuals affected with developmental disorders of speech and language have substantial difficulty acquiring expressive and/or receptive language in the absence of any profound sensory or neurological impairment and despite adequate intelligence and opportunity. Although studies of twins consistently indicate that a significant genetic component is involved, most families segregating speech and language deficits show complex patterns of inheritance, and a gene that predisposes individuals to such disorders has not been identified. We have studied a unique three-generation pedigree, KE, in which a severe speech and language disorder is transmitted as an autosomal-dominant monogenic trait. Our previous work mapped the locus responsible, SPCH1, to a 5.6-cM interval of region 7q31 on chromosome 7. We also identified an unrelated individual, CS, in whom speech and language impairment is associated with a chromosomal translocation involving the SPCH1 interval. Here we show that the gene FOXP2, which encodes a putative transcription factor containing a polyglutamine tract and a forkhead DNA-binding domain, is directly disrupted by the translocation breakpoint in CS. In addition, we identify a point mutation in affected members of the KE family that alters an invariant amino-acid residue in the forkhead domain. Our findings suggest that FOXP2 is involved in the developmental process that culminates in speech and language.
franziskaknolle.bsky.social
Unfortunately the Wi-Fi is very unstable in the room, which is why we need to refrain from having the session hybrid! Next time I’ll organise it better! 😕
franziskaknolle.bsky.social
I will see what I can do! I’ll post the link here if I get it to work or will let you know otherwise 🤞
franziskaknolle.bsky.social
No, just come by 😊! I hope you realised my typo, it’s happening this Tuesday September 30!
franziskaknolle.bsky.social
BTW it's happening on Sep 30 not Oct 30!!!
franziskaknolle.bsky.social
If you’re in #Munich 🥨 and curious about decision-making, perception, and cognition through a translational lens, join us for a seminar I’m hosting on Oct 30 with three fantastic speakers: @jkesby.bsky.social (visiting from 🇦🇺), @miguelbengala.bsky.social, and @jacob-lab.bsky.social 🧠💡
Reposted by Franziska Knolle
ondrejzika.bsky.social
🚨 I am over the moon 🌓 to announce that I am joining University College Dublin @ucddublin.bsky.social as an Assistant Professor this fall to start the Uncertain Mind (UMI) lab 💫

I am looking for PhD/Postdoc candidates to join (more below 👇 ). Please RT as the deadline is pretty soon 🙏
Reposted by Franziska Knolle
malcolmgcampbell.bsky.social
🚨Our preprint is online!🚨

www.biorxiv.org/content/10.1...

How do #dopamine neurons perform the key calculations in reinforcement #learning?

Read on to find out more! 🧵
Reposted by Franziska Knolle
freemanjb.bsky.social
New findings from my lab in Nature Communications suggest that racial stereotypes can lead the brain's perceptual system to temporarily "see" weapons where they don't exist.

Led by: @dongwonoh.bsky.social

Paper: www.nature.com/articles/s41...

(1/6)
Reposted by Franziska Knolle
tobiasuhauser.bsky.social
And another preprint from the lab: @lenarddome.bsky.social is presenting the CPM - a python toolbox that helps you model your tasks!
lenarddome.bsky.social
A new preprint 📝 with @tobiasuhauser.bsky.social @kenzakdr.bsky.social @benjwagner.bsky.social
and Andrew Webb accompanying our cpm-toolbox.net python modelling library - including details about our motivations, toolbox features, framework and workflows!

👉 osf.io/preprints/ps...
Reposted by Franziska Knolle
stanglab.bsky.social
Glad to share our new article out in
Cognitive Neuropsychiatry! We assessed relationships between symptoms and sentiment in speech during picture descriptions from people with psychosis across 2 cohorts and 2 timepoints... 1/4

doi.org/10.1080/1354...
Reposted by Franziska Knolle
rssmith.bsky.social
Big congrats to Marishka on this. I know how much time and effort went into it. Really happy to see it out! For those interested, she replicated prior longitudinal results using an approach-avoidance conflict task and showed how model parameters afforded out-of-sample clinical prediction.
cpsyjournal.bsky.social
New paper in CPsy - 'Computational Mechanisms of Approach-Avoidance Conflict Predictively Differentiate Between Affective and Substance Use Disorders' from Marishka Mehta and the group of @rssmith.bsky.social
doi.org/10.5334/cpsy...
Computational Mechanisms of Approach-Avoidance Conflict Predictively Differentiate Between Affective and Substance Use Disorders | Computational Psychiatry
doi.org
Reposted by Franziska Knolle
ted-satterthwaite.bsky.social
New preprint from stellar IRTG PhD student Amelie Rauland + team on white matter bundle reconstruction! Shows that WM bundles can be reliably extracted from simple 32-direction dMRI & features predict cognition - huge potential for legacy and clinical data. Thread 👇

www.biorxiv.org/cgi/content/...
Reposted by Franziska Knolle
actlab.bsky.social
New preprint from the lab! 🧠
Led by Juliana Trach, w/ Sophia Ou

Using fMRI, we discovered evidence for time-sensitive reward prediction errors (RPEs) in the human cerebellum.

Builds on, and extends, recent work in both rodents and NHPs
figure showing cerebellar RPE responses
Reposted by Franziska Knolle
degeelab.bsky.social
🧠✨ Exciting new research alert! ✨🧠

Did you know that catecholamines can reduce choice history biases in perceptual decision-making? 🧐🔍

Paper: journals.plos.org/plosbiology/...

With @donnerlab.bsky.social and @swammerdamuva.bsky.social
Reposted by Franziska Knolle
olufemiotaiwo.bsky.social
"Tao is one of the most prominent mathematicians and academics to publicly oppose the administration’s actions, calling them an “existential threat” to his field, and academic science, more broadly. He said public advocacy is a priority over his research, for now."

www.nbcnews.com/science/scie...
The 'Mozart of Math' rarely speaks about politics. The wide-ranging cuts to science funding made him change that.
UCLA's Terence Tao called the Trump administration's actions an "existential threat" to academic research in the U.S.
www.nbcnews.com