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Raquel Fueyo

@fueyoraquel.bsky.social

1K followers 580 following 84 posts

Incoming Group Leader @molgen | Postdoc in the Wysocka Lab at @ Stanford. @ EMBO, @ CancerResearch, and @ Leading Edge fellow. Gene regulation | Transposons | Human embryo development

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Raquel Fueyo @fueyoraquel.bsky.social · 7d

Today in @nature.com, we present our work leveraging functional genomics and human blastoids to uncover a human-specific mechanism in preimplantation development driven by the endogenous retrovirus HERVK.
Special thanks to the reviewers whose comments improved our manuscript a lot! rdcu.be/eI3tD

A human-specific regulatory mechanism revealed in a pre-implantation model

Nature - Genetic manipulation of blastoids reveals the role of recently emerged transposable elements and genes in human development.

rdcu.be

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Reposted by Raquel Fueyo

Aurora Ruiz-Herrera @aruizherrera.bsky.social · 1d

RIP John Gurdon

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Reposted by Raquel Fueyo

FragileNucleosome @fnucleosome.bsky.social · 1d

🎃 🥁This Wednesday in our 1st session of spookiest month👻 at #FragileNucleosome seminar, we are excited to host @sanimr.bsky.social & Alex Federation!
Register here for upcoming session and the entire series:
us06web.zoom.us/webinar/regi...

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Raquel Fueyo @fueyoraquel.bsky.social · 1d

Thank you! :)

Raquel Fueyo @fueyoraquel.bsky.social · 1d

Thank you! Yay!!!

Raquel Fueyo @fueyoraquel.bsky.social · 1d

Awww! Thank you! We will see each other more! :)

Raquel Fueyo @fueyoraquel.bsky.social · 2d

Alguno más hay, pero pocos jajajaja

Reposted by Raquel Fueyo

SEBD @sebioldev.bsky.social · Nov 18

We have gathered a Spanish Developmental Biology starter pack for those interested! Join the conversation and ask us to add you if you are not there yet! #DevBio go.bsky.app/UuRjx89

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Raquel Fueyo @fueyoraquel.bsky.social · 2d

Yes! Once I have my own funds! :)

Reposted by Raquel Fueyo

SEBD @sebioldev.bsky.social · 2d

We are very pleased to announce our joint meeting with the German @gfeev.bsky.social and the Dutch Developmental Biology Societies, which will take place in Potsdam from the 10-13th of March 2026. Registration is now open! www.uni-potsdam.de/en/gfe-meeti...

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Raquel Fueyo @fueyoraquel.bsky.social · 2d

Could you add me, please? Thanks!

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Raquel Fueyo @fueyoraquel.bsky.social · 2d

😂 Thank you Aydan!

Raquel Fueyo @fueyoraquel.bsky.social · 2d

I'm extremely grateful to my mentors (Joanna Wysocka and Marian Martinez-Balbas) who shaped the scientist I am today!

Raquel Fueyo @fueyoraquel.bsky.social · 2d

⚡⚡Excited to announce I'll be starting my lab at the Max Planck Institute of Molecular Genetics (@molgen.mpg.de) in Berlin in December! Leaving sunny California to join a fantastic environment with colleagues who do super cool work.
🔬🦠I'm hiring at all levels! 🔬🦠Check: www.molgen.mpg.de/fueyo-lab

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Raquel Fueyo @fueyoraquel.bsky.social · 2d

Congrats Edda and team! Cool work!

Reposted by Raquel Fueyo

Edda Schulz @eddaschulz.bsky.social · 2d

⚠️ Paper alert: Using a novel CRISPR screening approach, we mapped the entire regulatory network controlling Xist—key for X-chromosome inactivation.
👉 We discover how sex and development signals are decoded at a single gene locus.
www.nature.com/articles/s41...
👇 Bluetorial

Reporter CRISPR screens decipher cis-regulatory and trans-regulatory principles at the Xist locus - Nature Structural & Molecular Biology

Here Schwämmle et al. develop CRISPR reporter screens to map transcription-factor-regulatory element interactions at the Xist locus, revealing a two-step mechanism integrating developmental and X-dosage signals to initiate X-chromosome inactivation.

www.nature.com

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Reposted by Raquel Fueyo

CortésLab @corteslab.bsky.social · 4d

Kickstarting our Bluesky🦋 account with great news!
Our REPAIRome study finally out today in
@science.org
www.science.org/doi/10.1126/...

A comprehensive genetic catalog of human double-strand break repair

The analysis of DNA sequence outcomes provides molecular insights into double-strand break (DSB) repair mechanisms. Using parallel in-pool profiling of Cas9-induced insertions and deletions (indels) w...

www.science.org

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Raquel Fueyo @fueyoraquel.bsky.social · 4d

Thank you! I really appreciate it! We use cumate because the cells already grow under doxycycline to sustain the expression of NANOG and KLF2, two TFs that keep them pluripotent. Otherwise, we would have used doxycycline, in my experience, a much better inducible system than cumate.

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Raquel Fueyo @fueyoraquel.bsky.social · 4d

Thank you!

Raquel Fueyo @fueyoraquel.bsky.social · 4d

Muchas gracias Álvaro! A ver si nos vemos pronto!

Raquel Fueyo @fueyoraquel.bsky.social · 4d

Thank you Marco!

Raquel Fueyo @fueyoraquel.bsky.social · 5d

Awww!!! Congratulations Christa!

Raquel Fueyo @fueyoraquel.bsky.social · 5d

Thank you! They were truly surprising findings for us too!

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Reposted by Raquel Fueyo

Erin Doherty @erinedoherty.bsky.social · 6d

Now online at @nature.com we show how the Panoptes defense system protects against viruses that attempt immune evasion - and expands our understanding of the role of oligonucleotides in immunity.

Check out this work co-led with @benadler.bsky.social here:

www.nature.com/articles/s41...

A miniature CRISPR–Cas10 enzyme confers immunity by inhibitory signalling - Nature

Panoptes, an anti-phage defence system against virus-mediated immune suppression, is revealed.

www.nature.com

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Reposted by Raquel Fueyo

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 6d

Are you interested in a PhD in the area of "Mechanisms of translational control during embryogenesis?" Apply now for a PhD @mpi-cbg.de! Overview of all participating RGLs: imprs.mpi-cbg.de/5761/researc...

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Raquel Fueyo @fueyoraquel.bsky.social · 6d

I chatted with one of the @naturepodcast.bsky.social reporters about my recent work. The result here ⬇️⬇️⬇️.

Nature Podcast @naturepodcast.bsky.social · 7d

This week on the pod:

🦠 How ancient viruses drive modern human development
🧬 How heat can fuel DNA computers
go.nature.com/42QSI7W

Ancient viral DNA helps human embryos develop

Hear the biggest stories from the world of science | 01 October 2025

go.nature.com

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