@garyshiels.bsky.social
Reposted
Download our poster to learn how we applied Droplet Paired-Tag to Alzheimer's disease post-mortem brain tissue to reveal specific cellular changes and potential therapeutic targets
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
January 5, 2026 at 5:12 PM
Download our poster to learn how we applied Droplet Paired-Tag to Alzheimer's disease post-mortem brain tissue to reveal specific cellular changes and potential therapeutic targets
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
Reposted
Epigenetics Update - CDCA7 facilitates MET1-mediated CG DNA methylation maintenance in centromeric heterochromatin via linker histone H1 bit.ly/4pAjdbg
#Epigenetics #DNAm #Chromatin
---
High-resolution insights without cell sorting; epigenometech.com
#Epigenetics #DNAm #Chromatin
---
High-resolution insights without cell sorting; epigenometech.com
December 12, 2025 at 8:53 AM
Epigenetics Update - CDCA7 facilitates MET1-mediated CG DNA methylation maintenance in centromeric heterochromatin via linker histone H1 bit.ly/4pAjdbg
#Epigenetics #DNAm #Chromatin
---
High-resolution insights without cell sorting; epigenometech.com
#Epigenetics #DNAm #Chromatin
---
High-resolution insights without cell sorting; epigenometech.com
Reposted
Epigenetics Update – Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models go.nature.com/4rWwxIG
Marc Zuckermann/Ulrich Schüller in Nat Genet
#Epigenetic #DNAm #Cancer
---
Gain deeper insights at epigenometech.com
Marc Zuckermann/Ulrich Schüller in Nat Genet
#Epigenetic #DNAm #Cancer
---
Gain deeper insights at epigenometech.com
December 12, 2025 at 12:31 PM
Epigenetics Update – Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models go.nature.com/4rWwxIG
Marc Zuckermann/Ulrich Schüller in Nat Genet
#Epigenetic #DNAm #Cancer
---
Gain deeper insights at epigenometech.com
Marc Zuckermann/Ulrich Schüller in Nat Genet
#Epigenetic #DNAm #Cancer
---
Gain deeper insights at epigenometech.com
Reposted
Learn how we used Droplet Paired-Tag to assess RNA expression and histone modifications in individual brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
December 12, 2025 at 5:18 PM
Learn how we used Droplet Paired-Tag to assess RNA expression and histone modifications in individual brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
Reposted
Epigenetics Update - Age- and cell-type-specific effects of histone variant H2BE in the brain bit.ly/4oM02Kd
Erica Korb (University of Pennsylvania) reporting in Cell Rep
#Epigenetics #HistoneVariants #H2BE #Aging
---
High-resolution insights without cell sorting; epigenometech.com
Erica Korb (University of Pennsylvania) reporting in Cell Rep
#Epigenetics #HistoneVariants #H2BE #Aging
---
High-resolution insights without cell sorting; epigenometech.com
December 15, 2025 at 8:29 AM
Epigenetics Update - Age- and cell-type-specific effects of histone variant H2BE in the brain bit.ly/4oM02Kd
Erica Korb (University of Pennsylvania) reporting in Cell Rep
#Epigenetics #HistoneVariants #H2BE #Aging
---
High-resolution insights without cell sorting; epigenometech.com
Erica Korb (University of Pennsylvania) reporting in Cell Rep
#Epigenetics #HistoneVariants #H2BE #Aging
---
High-resolution insights without cell sorting; epigenometech.com
Reposted
Epigenetics Update - The Histone Methyltransferase KMT2D is a Critical Mediator of Lineage Plasticity and Therapeutic Response in Castration Resistant Prostate Cancer bit.ly/4a8C1cI
#Epigenetics #KMT2D #Cancer #CRPC
---
Discover the breakthrough at epigenometech.com
#Epigenetics #KMT2D #Cancer #CRPC
---
Discover the breakthrough at epigenometech.com
The Histone Methyltransferase KMT2D is a Critical Mediator of Lineage Plasticity and Therapeutic Response in Castration Resistant Prostate Cancer
Abstract. Castration-resistant prostate cancer (CRPC) is largely dependent on the androgen receptor (AR) for growth and often exhibits hyperactive PI3K signaling, most frequently due to PTEN loss. The...
bit.ly
December 15, 2025 at 1:25 PM
Epigenetics Update - The Histone Methyltransferase KMT2D is a Critical Mediator of Lineage Plasticity and Therapeutic Response in Castration Resistant Prostate Cancer bit.ly/4a8C1cI
#Epigenetics #KMT2D #Cancer #CRPC
---
Discover the breakthrough at epigenometech.com
#Epigenetics #KMT2D #Cancer #CRPC
---
Discover the breakthrough at epigenometech.com
Reposted
Download our poster to learn how we applied Droplet Paired-Tag to Alzheimer's disease post-mortem brain tissue to reveal specific cellular changes and potential therapeutic targets
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
December 15, 2025 at 4:39 PM
Download our poster to learn how we applied Droplet Paired-Tag to Alzheimer's disease post-mortem brain tissue to reveal specific cellular changes and potential therapeutic targets
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
Reposted
New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
November 24, 2025 at 4:15 PM
New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
Reposted
Epigenetics Update - Engineered chromatin readers track damaged chromatin dynamics in live cells and animals go.nature.com/4ikfHPs
Richard Cardoso da Silva and Tuncay Baubec reporting in Nat Commun
#Epigenetics #Chromatin
---
Gain deeper insights into gene regulation; epigenometech.com
Richard Cardoso da Silva and Tuncay Baubec reporting in Nat Commun
#Epigenetics #Chromatin
---
Gain deeper insights into gene regulation; epigenometech.com
November 25, 2025 at 8:28 AM
Epigenetics Update - Engineered chromatin readers track damaged chromatin dynamics in live cells and animals go.nature.com/4ikfHPs
Richard Cardoso da Silva and Tuncay Baubec reporting in Nat Commun
#Epigenetics #Chromatin
---
Gain deeper insights into gene regulation; epigenometech.com
Richard Cardoso da Silva and Tuncay Baubec reporting in Nat Commun
#Epigenetics #Chromatin
---
Gain deeper insights into gene regulation; epigenometech.com
Reposted
Epigenome Technologies offers an end-to-end single-cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA and epigenetic marks (we run the workflow on your samples) from preparation to data analysis
#Epigenetics #SingleCell #PairedTag #Multiomics
bit.ly/3HWFoaw
#Epigenetics #SingleCell #PairedTag #Multiomics
bit.ly/3HWFoaw
November 25, 2025 at 4:39 PM
Epigenome Technologies offers an end-to-end single-cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA and epigenetic marks (we run the workflow on your samples) from preparation to data analysis
#Epigenetics #SingleCell #PairedTag #Multiomics
bit.ly/3HWFoaw
#Epigenetics #SingleCell #PairedTag #Multiomics
bit.ly/3HWFoaw
Reposted
We have recently expanded our single-cell epigenetics assays!
Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIPseq platform
Learn more at lnkd.in/g3YqPrWY
#SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq
Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIPseq platform
Learn more at lnkd.in/g3YqPrWY
#SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq
November 14, 2025 at 4:54 PM
We have recently expanded our single-cell epigenetics assays!
Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIPseq platform
Learn more at lnkd.in/g3YqPrWY
#SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq
Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIPseq platform
Learn more at lnkd.in/g3YqPrWY
#SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq
Reposted
Calling all neurobiologists with an interest in epigenetics, single cell epigenomics,....and FREE BEER!!!
Join us for craft beers, bites, and brain-related science discussions in the East Village - a short 10-minute walk from the San Diego Convention Center!
RSVP: lnkd.in/gjNWFmrh
Join us for craft beers, bites, and brain-related science discussions in the East Village - a short 10-minute walk from the San Diego Convention Center!
RSVP: lnkd.in/gjNWFmrh
November 13, 2025 at 7:44 AM
Calling all neurobiologists with an interest in epigenetics, single cell epigenomics,....and FREE BEER!!!
Join us for craft beers, bites, and brain-related science discussions in the East Village - a short 10-minute walk from the San Diego Convention Center!
RSVP: lnkd.in/gjNWFmrh
Join us for craft beers, bites, and brain-related science discussions in the East Village - a short 10-minute walk from the San Diego Convention Center!
RSVP: lnkd.in/gjNWFmrh
Reposted
Join us at Neuroscience 2025 if you have an interest in single cell epigenetics including single cell CUT&Tag!
Drop by our booth from November 16th-19th at the San Diego Convention Center!
#Epigenetics #EpigenomeTech #PairedTag #SingleCell #CUTandTag
Drop by our booth from November 16th-19th at the San Diego Convention Center!
#Epigenetics #EpigenomeTech #PairedTag #SingleCell #CUTandTag
November 13, 2025 at 1:01 PM
Join us at Neuroscience 2025 if you have an interest in single cell epigenetics including single cell CUT&Tag!
Drop by our booth from November 16th-19th at the San Diego Convention Center!
#Epigenetics #EpigenomeTech #PairedTag #SingleCell #CUTandTag
Drop by our booth from November 16th-19th at the San Diego Convention Center!
#Epigenetics #EpigenomeTech #PairedTag #SingleCell #CUTandTag
Reposted
Learn how we applied Droplet Paired-Tag to Alzheimer's disease post-mortem brain tissue to reveal specific cellular changes and potential therapeutic targets
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
November 13, 2025 at 4:06 PM
Learn how we applied Droplet Paired-Tag to Alzheimer's disease post-mortem brain tissue to reveal specific cellular changes and potential therapeutic targets
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
Reposted
Learn how we used Droplet Paired-Tag to assess RNA expression and his mods in individual brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
November 11, 2025 at 4:20 PM
Learn how we used Droplet Paired-Tag to assess RNA expression and his mods in individual brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
Reposted
New Epigenome Technologies Blog post! bit.ly/4oyZZ55
"Can Identifying the Cell-of-Origin and Epigenetic Targets Halt Prostate Cancer in its Tracks?"
Based on a Nature Genetics paper from Weiran Feng and Erik Ladewig
#Epigenetics #Blog #EpigenomeTech #ProstateCancer
"Can Identifying the Cell-of-Origin and Epigenetic Targets Halt Prostate Cancer in its Tracks?"
Based on a Nature Genetics paper from Weiran Feng and Erik Ladewig
#Epigenetics #Blog #EpigenomeTech #ProstateCancer
November 12, 2025 at 4:45 PM
New Epigenome Technologies Blog post! bit.ly/4oyZZ55
"Can Identifying the Cell-of-Origin and Epigenetic Targets Halt Prostate Cancer in its Tracks?"
Based on a Nature Genetics paper from Weiran Feng and Erik Ladewig
#Epigenetics #Blog #EpigenomeTech #ProstateCancer
"Can Identifying the Cell-of-Origin and Epigenetic Targets Halt Prostate Cancer in its Tracks?"
Based on a Nature Genetics paper from Weiran Feng and Erik Ladewig
#Epigenetics #Blog #EpigenomeTech #ProstateCancer
Reposted
New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks.
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
October 21, 2025 at 3:59 PM
New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks.
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
Reposted
Epigenome Technologies have recently expanded their single cell epigenetics assays
Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIPseq platform
Learn more at lnkd.in/g3YqPrWY
#SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq
Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIPseq platform
Learn more at lnkd.in/g3YqPrWY
#SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq
October 21, 2025 at 7:02 PM
Epigenome Technologies have recently expanded their single cell epigenetics assays
Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIPseq platform
Learn more at lnkd.in/g3YqPrWY
#SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq
Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIPseq platform
Learn more at lnkd.in/g3YqPrWY
#SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq
Reposted
Epigenetics Update - Reporter CRISPR screens decipher cis-regulatory and trans-regulatory principles at the Xist locus go.nature.com/42vdHgt
Edda G. Schulz reporting in NSMB
#Epigenetics #CRISPR #Chromatin #Xist
---
Discover the breakthrough at epigenometech.com
Edda G. Schulz reporting in NSMB
#Epigenetics #CRISPR #Chromatin #Xist
---
Discover the breakthrough at epigenometech.com
October 13, 2025 at 11:21 AM
Epigenetics Update - Reporter CRISPR screens decipher cis-regulatory and trans-regulatory principles at the Xist locus go.nature.com/42vdHgt
Edda G. Schulz reporting in NSMB
#Epigenetics #CRISPR #Chromatin #Xist
---
Discover the breakthrough at epigenometech.com
Edda G. Schulz reporting in NSMB
#Epigenetics #CRISPR #Chromatin #Xist
---
Discover the breakthrough at epigenometech.com
Reposted
Download our poster to learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics
bit.ly/4kgWMF3
October 13, 2025 at 3:27 PM
Download our poster to learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics
bit.ly/4kgWMF3
Reposted
New from Epigenome Technologies: the first fully validated Single-Cell CUT&Tag kit
Fully compatible with 10x Chromium® (ATAC) or Fluent PiP-seq®
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4lquJDv
Fully compatible with 10x Chromium® (ATAC) or Fluent PiP-seq®
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4lquJDv
October 6, 2025 at 3:59 PM
New from Epigenome Technologies: the first fully validated Single-Cell CUT&Tag kit
Fully compatible with 10x Chromium® (ATAC) or Fluent PiP-seq®
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4lquJDv
Fully compatible with 10x Chromium® (ATAC) or Fluent PiP-seq®
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4lquJDv
Reposted
We are proud to announce that the Epigenome Technologies CTO, Chris Hartl, will be discussing Paired-Tag at @washumedicine.bsky.social on Wednesday, 8th October!
We hope to see you there! bit.ly/4mJk3A4
#EpigenomeTech #PairedTag #SingleCell #Epigenetics
We hope to see you there! bit.ly/4mJk3A4
#EpigenomeTech #PairedTag #SingleCell #Epigenetics
October 6, 2025 at 7:12 PM
We are proud to announce that the Epigenome Technologies CTO, Chris Hartl, will be discussing Paired-Tag at @washumedicine.bsky.social on Wednesday, 8th October!
We hope to see you there! bit.ly/4mJk3A4
#EpigenomeTech #PairedTag #SingleCell #Epigenetics
We hope to see you there! bit.ly/4mJk3A4
#EpigenomeTech #PairedTag #SingleCell #Epigenetics
Reposted
Epigenetics Update - Activation of epigenetic reprogramming via crotonylation overcomes resistance to EGFR-TKI therapy in lung cancer bit.ly/3IDQSAA
Lihui Wang reporting in PNAS
#Epigenetics #Crotonylation #Cancer
---
Gain deeper insights into gene regulation; epigenometech.com
Lihui Wang reporting in PNAS
#Epigenetics #Crotonylation #Cancer
---
Gain deeper insights into gene regulation; epigenometech.com
Activation of epigenetic reprogramming via crotonylation overcomes resistance to EGFR-TKI therapy in lung cancer | PNAS
Posttranslational modifications (PTMs) on histones play critical roles in cellular
processes, including gene expression and tumorigenesis. However,...
bit.ly
October 7, 2025 at 7:22 AM
Epigenetics Update - Activation of epigenetic reprogramming via crotonylation overcomes resistance to EGFR-TKI therapy in lung cancer bit.ly/3IDQSAA
Lihui Wang reporting in PNAS
#Epigenetics #Crotonylation #Cancer
---
Gain deeper insights into gene regulation; epigenometech.com
Lihui Wang reporting in PNAS
#Epigenetics #Crotonylation #Cancer
---
Gain deeper insights into gene regulation; epigenometech.com
Reposted
Epigenome Technologies offers an end-to-end Single-Cell CUT&Tag service
Our expert scientists run the entire workflow on your samples - from preparation to data analysis
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4kPxe2i
Our expert scientists run the entire workflow on your samples - from preparation to data analysis
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4kPxe2i
October 7, 2025 at 4:05 PM
Epigenome Technologies offers an end-to-end Single-Cell CUT&Tag service
Our expert scientists run the entire workflow on your samples - from preparation to data analysis
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4kPxe2i
Our expert scientists run the entire workflow on your samples - from preparation to data analysis
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4kPxe2i
Reposted
We are proud to announce that the Epigenome Technologies CTO, Chris Hartl, will be discussing Paired-Tag at the @upenn.edu Epigenetics Institute on Thursday, 9th October!
We hope to see you there! bit.ly/4pT78yl
#EpigenomeTech #PairedTag #SingleCell #Epigenetics
We hope to see you there! bit.ly/4pT78yl
#EpigenomeTech #PairedTag #SingleCell #Epigenetics
October 7, 2025 at 6:52 PM
We are proud to announce that the Epigenome Technologies CTO, Chris Hartl, will be discussing Paired-Tag at the @upenn.edu Epigenetics Institute on Thursday, 9th October!
We hope to see you there! bit.ly/4pT78yl
#EpigenomeTech #PairedTag #SingleCell #Epigenetics
We hope to see you there! bit.ly/4pT78yl
#EpigenomeTech #PairedTag #SingleCell #Epigenetics