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Genomics Guy
@genomicssalesguy.bsky.social
NGS, Single cell, Spatial, RNA, DNA, PCR, qPCR, Genes
Reposted by Genomics Guy
What are #UMIs?

UMIs are short, random #nucleotide sequences added to individual #transcripts during library preparation and uniquely identify #cDNA. Learn how this powerful tool cleans up #RNASeq data for #GeneExpression analysis, resulting in improved #RNA-Seq data.

Read now: hubs.ly/Q03nSq1g0
How to Improve Your RNA-Seq Data with UMIs and ERCC RNA
Scientists have developed two powerful tools for RNA sequencing (RNA-Seq) experiments to minimize bias and variability: unique molecular identifiers (UMIs) and ERCC RNA spike-ins. We’ll cover the basi...
hubs.ly
June 6, 2025 at 2:15 PM
Reposted by Genomics Guy
With direct in sample sequencing (DISS), you can get targeted RNA, 3’ whole transcriptome, protein 🧬, and morphology 🔬 data all from the same cells. It’s multimodal, customizable, and fast. Watch the on-demand webinar to see how DISS on #AVITI24 can accelerate your research. ▶️ bit.ly/42XOGtN
June 6, 2025 at 4:18 PM
Reposted by Genomics Guy
Thrilled to announce I'm moving to Manchester to lead the Cancer Origins group! If you're interested in how mutations and exposures drive tumourigenesis — come join the adventure
We are recruiting two exciting #Postdoctoral roles:

🧪 Work with @clausjorgensen.bsky.social on targeting the tumour #microenvironment in #PancreaticCancer

🥼 Join @drwilliamhill.bsky.social to study air pollution & #LungCancer

Full details of both positions at:
www.cruk.manchester.ac.uk/careers/
June 6, 2025 at 3:32 PM
Congratulations 👏🏼
🔬 Meet #AVITI24 grant winner Jessica Nordlund, PhD (SciLifeLab Uppsala), recognized for her work on how chemotherapy impacts cellular responses to immunotherapy. Her team will use Teton’s multiomic spatial profiling to explore tumor-immune interactions. Congratulations! #Multiomics #GrantProgram
June 3, 2025 at 7:15 PM
Reposted by Genomics Guy
Graduate students, postdocs and science lab leaders are reeling after an announcement last week that the US government will revoke visas for Chinese students — and they are contacting lawyers.

https://go.nature.com/4mLQ9fU
‘You’re just not welcome’: researchers grapple with US plan to revoke Chinese student visas
Scientists are eyeing their legal options in anticipation of new immigration actions.
go.nature.com
June 3, 2025 at 7:08 PM
Reposted by Genomics Guy
Last week at Oz Single Cell Sydney, we connected with brilliant minds in #singlecell and spatial biology. Thanks to all who joined our talk on "High Dimensional Biology Powered by #AVITI24". 📸 Big shoutout to the Australian scientific community—your energy was incredible! #OzSingleCell25
May 29, 2025 at 10:30 PM
Reposted by Genomics Guy
MIC-Drop-seq: Scalable single-cell phenotyping of mutant vertebrate embryos https://www.biorxiv.org/content/10.1101/2025.05.27.656468v1
May 30, 2025 at 4:35 AM
Reposted by Genomics Guy
Resolving the full set of human polymorphic inversions and other complex variants from ultra-long read data https://www.biorxiv.org/content/10.1101/2025.05.27.656315v1
May 30, 2025 at 7:34 AM
Reposted by Genomics Guy
The fantastic lineup for our latest webinar series, Unlocking the Epigenome: Precision Tools for Complex Diseases, includes: @chiaraherzog.bsky.social, @a-radzisheuskaya.bsky.social, @sankarinagarajan.bsky.social, @sebpreissl.bsky.social, @scherermich.bsky.social, and more! Check them out below!
How can cutting-edge tech help decode the complex #epigenome to reveal disease mechanisms, biomarkers & new therapies? Join us for the Unlocking the Epigenome: Precision Tools for Complex Diseases webinar series to find out. #epigenetics
Register now: hubs.la/Q03pFXJk0
May 29, 2025 at 12:01 PM
The Fred Hutch lab has done this before. Interesting to see how different company's technologies compare in real world labs.

#singlecell #comparingtech
May 28, 2025 at 7:23 AM
With one high profile litigation coming to an end in the Genomics sphere, another one begins:

Illumina v Element Biosciences.

Not read much into it yet. What are your thoughts? Similar feelings to that of the 10x v Nanostring(Bruker) saga?
May 16, 2025 at 3:23 PM
For those in the UK BioPharma field, this may be of interest to you.

#biopharma #genomics #spatial
Join us at the BioPharma Summit Cambridge, UK on May 20, dedicated to the latest advancements and innovations in biopharma. This is a unique opportunity to connect with industry leaders, researchers, and innovators who are shaping the future of biopharma. Register at bit.ly/4ddQJPb
May 13, 2025 at 10:54 AM
Reposted by Genomics Guy
🌟 A new week, a new pre-print! See how we used AVITI24™ to study TKI resistance in NSCLC with single cell co-detection of RNA, protein, and morphology and identified CDK4/6 as a route of cell survival. 📖 Read the paper: bit.ly/3Fe3exr
Unraveling Tyrosine-Kinase Inhibitor Resistance in NSCLC Cells via Same-cell Measurement of RNA, Protein, and Morphological Responses
Non-small cell lung cancer (NSCLC) frequently develops resistance to tyrosine kinase inhibitors (TKIs), limiting the long-term success of targeted therapies. A deeper understanding of resistance mecha...
bit.ly
May 12, 2025 at 10:27 PM
Another company enters the Spatial market. What impact will this have?

www.illumina.com/company/news...
Illumina unveils first-of-its-kind spatial transcriptomics technology
www.illumina.com
February 19, 2025 at 3:27 PM
With #AGBT nearly upon us there are a lot of rumors around #Roche and a new sequencer to rival #illumina. Is illumina's dominance slowly eroding? Would you still buy an illumina system if funds available?
February 15, 2025 at 11:03 AM
Reposted by Genomics Guy
Detecting Non-linear Dependence through Genome Wide Analysis https://www.biorxiv.org/content/10.1101/2025.02.12.637804v1
February 14, 2025 at 8:32 AM
This is massive, looking forward to keeping an eye on these fascinating collaborations between "New" sequencing platforms and @10xgenomics.bsky.social
Creating the largest #singlecell dataset ever will take dedication, collaboration & high-performance tools. We’re thrilled the @chanzuckerberg.bsky.social Billion Cells Project will pair GEM-X tech with Ultima Genomics sequencing to achieve this landmark scale. Learn more: bit.ly/4aRaScr
February 7, 2025 at 11:48 AM
First major get together of all like minded people. Get along and interact with all the companies that will be there highlighting their latest technologies.

#fog2025
Don't forget to get your ticket for The Festival of Genomics & Biodata in London next month, the UK's largest life science event. Learn more here: hubs.ly/Q02-RWvR0

#FOG2025 #genomics
January 15, 2025 at 6:13 PM