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Paulo Navarro-Costa

@germcells.bsky.social

160 followers 89 following 280 posts

Group leader studying reproduction and infertility | Quality Assurance Manager | Invited Assistant Professor | Perennial outsider | DIY aesthete 🇵🇹🇬🇧🇪🇺 Lab website: www.evorepromed.pt

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Paulo Navarro-Costa @germcells.bsky.social · Nov 19

They said it, not us...😇 Our "fundamental" and "convincing" study on what evolution can teach us about #infertility is finally out. TL;DR? Check out this primer by @elife.bsky.social to get the lowdown on what we discovered by looking at the past of human sperm. elifesciences.org/digests/9577...

How to build a sperm cell

A shared set of old, deeply conserved genes presides over the development of sperm cells in humans, mice and fruit flies.

elifesciences.org

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Paulo Navarro-Costa @germcells.bsky.social · 21h

John Gurdon, yr beloved @germcells.bsky.social first and foremost scientific reference has passed away. Here's to a person who was told he couldn't make it and decided to make it on his own terms 🥂 Rest in power, John!

Reposted by Paulo Navarro-Costa

Jason Shepherd @jasonsynaptic.bsky.social · 1d

#goals

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Paulo Navarro-Costa @germcells.bsky.social · 6d

Great work from Aurora's lab! 👌

Aurora Ruiz-Herrera @aruizherrera.bsky.social · 7d

🚨 New from our lab in #ScienceAdvances!

RAD21L cohesin acts as both a 3D genome architect and a transcriptional gatekeeper in the male germline. Its loss disrupts both structure and function—highlighting the tight link between genome folding and gene regulation

www.science.org/doi/10.1126/...

Meiotic cohesin RAD21L shapes 3D genome structure and transcription in the male germline

Deletion of the meiotic subunit RAD21L alters 3D chromatin structure and transcription in the mammalian male germ line.

www.science.org

Paulo Navarro-Costa @germcells.bsky.social · 6d

Super cool! Congrats to the team! 🙌

Paulo Navarro-Costa @germcells.bsky.social · 7d

Semester's off to a promising start. Histology student in a Clash T-shirt asks what's my favorite Descendents record 🙌

Paulo Navarro-Costa @germcells.bsky.social · 12d

Ou 1001, neste país onde a noite começou a cair a um ritmo assustador.

Paulo Navarro-Costa @germcells.bsky.social · 13d

👏👏👏 www.publico.pt/2025/09/26/c...

Cem matemáticos escrevem carta aberta ao ministro da Ciência

A fusão das entidades para a ciência fundamental e a inovação preocupa-nos, pois torna o caso português isolado e contracorrente face às práticas dos países cientificamente evoluídos.

www.publico.pt

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Paulo Navarro-Costa @germcells.bsky.social · 18d

👏👏👏 Truly well-deserved @needhibhalla.bsky.social 🏆

American Society for Cell Biology @ascbiology.bsky.social · 19d

🎉 Congratulations to Needhi Bhalla, UC Santa Cruz (www.bhallalab.com
), named a 2025 #ASCB Fellow! This honor celebrates her outstanding contributions to cell biology, leadership, & service. Fellows will be recognized at #CellBio2025 in Philadelphia this December. #CellBiology

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Paulo Navarro-Costa @germcells.bsky.social · 18d

Notes on method by Hayao Miyazaki.

Paulo Navarro-Costa @germcells.bsky.social · 29d

Mais um dia normal na #Fertagus. Homem com duas crianças tem ataque de pânico em carruagem com lotação máxima excedida e ativa abertura de porta de emergência (com comboio prestes a iniciar marcha). Vai ser preciso morrer alguém para este serviço funcionar com um pingo de humanidade?

Reposted by Paulo Navarro-Costa

Thiago Carvalho @cyrilpedia.bsky.social · Sep 5

'Overall, the message from this survey is positive– evolutionary biologists are readily employable outside of academia, generally well-prepared for those jobs, and report high levels of satisfaction in their non-academic careers.'
#Preprint
www.biorxiv.org/content/10.1...

Leaving Academia: Insights from Evolutionary Biologists on Their Career Transitions and Job Satisfaction

Many who have obtained PhDs in evolutionary biology will ultimately pursue careers that fall outside a narrow definition of an academic career. At the same time, PhD students and supervisors of PhD st...

www.biorxiv.org

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Paulo Navarro-Costa @germcells.bsky.social · Sep 5

Neste novo paradigma da educação, ciência e inovação, dar e devolver são conceitos fundamentais.
www.publico.pt/2025/09/05/s...

Reitor do Porto denuncia “pressões” para aceitar entradas ilegais em Medicina. Ministro nega

Reitor revelou ao Expresso ter sido pressionado por pessoas “influentes e com acesso ao poder”. Ministro da Educação intercedeu por alunos, mas nega pressões. Parecer deu razão ao reitor.

www.publico.pt

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Paulo Navarro-Costa @germcells.bsky.social · Sep 3

Só deixar isto aqui...

SAPO @sapo.pt · Jul 11

Comboios avariam todos os dias e utentes exigem inspeção urgente à Fertagus

Utentes da Fertagus exigem inspeção urgente aos comboios. Avarias constantes e comboios cheios geram revolta. Governo pressionado.

www.sapo.pt

Paulo Navarro-Costa @germcells.bsky.social · Sep 3

Fertagus, here looking at you, MFs 👆

Paulo Navarro-Costa @germcells.bsky.social · Sep 3

Back in the 90s every so often I would ride this tram to go to punk rock shows in a dive bar on top of the hill. Lisbon (or whatever's left of that once fabled city) is coming apart. Peace to those who have fallen and to their loved ones 💔

The New York Times @nytimes.com · Sep 3

Breaking News: At least 15 people are dead and 18 others injured after a popular funicular in Lisbon, the Elevador da Glória, derailed and crashed. nyti.ms/4n6YDxo

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Reposted by Paulo Navarro-Costa

Alberto de la Iglesia @albiglero.bsky.social · Sep 1

Last week to submit your abstract! Don’t miss the chance to share your work with us at the next #POHaD GdR Symposium

@gdr-reproduction.bsky.social @juliecocquet.bsky.social #epigenetics #sperm #andrology #offspringhealth #dohad

gdr-reproduction.bsky.social @gdr-reproduction.bsky.social · Jul 4

📢 Save the date!
The GdR Symposium on POHaD: Paternal Origins of Health and Disease is happening Oct 16, 2025 — hybrid at Institut Cochin (Paris) & online.

📌 Free registration (required): forms.gle/TTaFbuNJmwtx...

#POHaD #Epigenetics #Reproduction
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Registration form - POHaD GdR Symposium

By filling this form, you will confirm your registration to the upcoming POHaD hybrid Symposium taking place next October 16th, 2025. Registration is free of cost but mandatory. Abstract submission is...

forms.gle

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Paulo Navarro-Costa @germcells.bsky.social · Aug 30

Mas afinal é para devolvermos à sociedade ou à economia?

Paulo Navarro-Costa @germcells.bsky.social · Aug 18

"This story shows that it is possible to establish a multibillion-dollar industry purely by letting scientists communicate their research, exchange information and share materials."

www.nature.com/articles/d41...

Monoclonal antibodies revolutionized biomedical science and health care

The story of the discovery of these molecules 50 years ago shows how the free exchange of ideas can lead to life-changing treatments.

www.nature.com

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Paulo Navarro-Costa @germcells.bsky.social · Aug 14

Peepz, it's #Tbt of that mytical #GRC on fertilization in NH. Here's the #Drosophila dream team: Yukiko Yamashita (r) and Benjamin Loppin (c), with yr beloved water boy @germcells.bsky.social on the left 😅

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Paulo Navarro-Costa @germcells.bsky.social · Aug 14

🤬
www.thetransmitter.org/community/ha...

Exclusive: Harvard University lays off fly database team

The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.

www.thetransmitter.org

Paulo Navarro-Costa @germcells.bsky.social · Aug 14

À atenção do Governo de Portugal.

BWJones @bwjones.bsky.social · Aug 14

Science is a long game.

Translational science, or clinical medicine is only possibly because of basic science discoveries where the clinical applications are not yet known.

Also: Nobels are typically awarded for basic science… *exploratory* basic science.

True story.

Ardem Patapoutian @ardemp.bskyverified.social · Aug 13

Over 20 years after Julius’s lab and mine cloned TRPM8, it is rewarding to see this science helping patients. The TRPM8 agonist Tryptyr treats dry eye by increasing tear production. A reminder that NIH-funded curiosity-driven research translates to medicines.
tryptyr.myalcon.com?gad_source=1...

Reposted by Paulo Navarro-Costa

Ethan Freedman @ethanpfreedman.com · Aug 13

What if instead…. Health insurance

Matt Seybold @mattseybold.bsky.social · Aug 13

Made in a lab to make other billionaires seem more palatable.

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Paulo Navarro-Costa @germcells.bsky.social · Aug 13

Agosto na #Fertagus é sem ar condicionado e connosco, o proletariado, a bombar (que remédio) ♨️

Paulo Navarro-Costa @germcells.bsky.social · Aug 13

plz send me a DM / email

Paulo Navarro-Costa @germcells.bsky.social · Aug 13

"Sutanjang was a line of division on the road that separated the incarcerated from their children. The patients were allowed to see their children once a month from a distance at this line, because of fear of infection."
hekint.org/2020/12/30/t...

The Sorokdo National Hospital of South Korea - Hektoen International

Lucy EumNew Brunswick, Canada Hansen’s disease, also known as leprosy, has historically been a highly stigmatized condition.1 For centuries it was thought to be a curse, a punishment for sin, or a her...

hekint.org