Giulio Maria Pasinetti, MD, PhD
@giuliompasinetti.bsky.social
Creating a culture of innovation that emphasizes creativity, disruptive thinking, and interdisciplinary collaboration to understand and promote neuroresilience.
Knowledge of modifiable factors influencing age at onset of #AlzheimersDisease remains limited. In this study, Yi-Ju Li, Eden Martin, et al. utilized genetic information to uncover such factors. FULL STUDY @alzdemjournals.bsky.social 👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
February 9, 2026 at 4:31 PM
Knowledge of modifiable factors influencing age at onset of #AlzheimersDisease remains limited. In this study, Yi-Ju Li, Eden Martin, et al. utilized genetic information to uncover such factors. FULL STUDY @alzdemjournals.bsky.social 👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Here, researchers Sarah Shipley, Caswell Barry, et al. investigated how disruptions in hippocampal reactivations relate to place cell stability and spatial memory deficits in #AlzheimersDisease mouse model. @ucl.ac.uk @currentbiology.bsky.social @cellpress.bsky.social 👉 www.cell.com/current-biol...
February 2, 2026 at 4:41 PM
Here, researchers Sarah Shipley, Caswell Barry, et al. investigated how disruptions in hippocampal reactivations relate to place cell stability and spatial memory deficits in #AlzheimersDisease mouse model. @ucl.ac.uk @currentbiology.bsky.social @cellpress.bsky.social 👉 www.cell.com/current-biol...
In this study, researchers Rachael Layden, Jenna Groh, Annalise Miner, et al. examined the independent contribution of #CTE neuropathology w/ #Dementia & cognitive symptoms. @alzdemjournals.bsky.social @alzassociation.bsky.social 👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
January 30, 2026 at 10:39 PM
In this study, researchers Rachael Layden, Jenna Groh, Annalise Miner, et al. examined the independent contribution of #CTE neuropathology w/ #Dementia & cognitive symptoms. @alzdemjournals.bsky.social @alzassociation.bsky.social 👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
In a NEW STUDY, researchers Barbara Brott, Aram Raissi, Carla Shatz, et al. report new evidence that amyloid beta & inflammation may act through same molecular pathway. This insight may have important implications for future #AlzheimersDisease therapies. @pnas.org 👉 www.pnas.org/doi/10.1073/...
January 28, 2026 at 6:13 PM
In a NEW STUDY, researchers Barbara Brott, Aram Raissi, Carla Shatz, et al. report new evidence that amyloid beta & inflammation may act through same molecular pathway. This insight may have important implications for future #AlzheimersDisease therapies. @pnas.org 👉 www.pnas.org/doi/10.1073/...
Here, Michael Pomirchy, Pascal Geldsetzer, et al. found that vaccination against #Herpes zoster ( #Shingles ) was tied to significantly less #Dementia risk. @stanfordpress.bsky.social
@mcmasteruniversity.bsky.social Learn More @thelancet.com
👉 thelancet.com/journals/lan...
@mcmasteruniversity.bsky.social Learn More @thelancet.com
👉 thelancet.com/journals/lan...
January 27, 2026 at 4:15 PM
Here, Michael Pomirchy, Pascal Geldsetzer, et al. found that vaccination against #Herpes zoster ( #Shingles ) was tied to significantly less #Dementia risk. @stanfordpress.bsky.social
@mcmasteruniversity.bsky.social Learn More @thelancet.com
👉 thelancet.com/journals/lan...
@mcmasteruniversity.bsky.social Learn More @thelancet.com
👉 thelancet.com/journals/lan...
Researchers @unmhsc.bsky.social have shown OTULIN, an enzyme known for regulating immune activity, plays major role in producing tau. Disabling OTULIN stopped tau production & removed existing tau from neurons @uthsc.bsky.social @genomicpress.bsky.social👉 genomicpress.kglmeridian.com/view/journal...
January 20, 2026 at 2:11 PM
Researchers @unmhsc.bsky.social have shown OTULIN, an enzyme known for regulating immune activity, plays major role in producing tau. Disabling OTULIN stopped tau production & removed existing tau from neurons @uthsc.bsky.social @genomicpress.bsky.social👉 genomicpress.kglmeridian.com/view/journal...
"Darkness cannot drive out darkness; only light can do that… the time is always right to do what is right”. - Dr. Martin Luther King Jr.
On January 19th, celebrate the life and legacy of Dr. Martin Luther King Jr., a great American hero!
On January 19th, celebrate the life and legacy of Dr. Martin Luther King Jr., a great American hero!
January 18, 2026 at 2:34 PM
"Darkness cannot drive out darkness; only light can do that… the time is always right to do what is right”. - Dr. Martin Luther King Jr.
On January 19th, celebrate the life and legacy of Dr. Martin Luther King Jr., a great American hero!
On January 19th, celebrate the life and legacy of Dr. Martin Luther King Jr., a great American hero!
Brian Kennedy, et al. of National University of Singapore report calcium alpha-ketoglutarate (CaAKG), naturally occurring & well studied metabolite linked to healthy aging, can reverse several memory related brain functions disrupted in #Alzheimers Aging Cell👉 onlinelibrary.wiley.com/doi/10.1111/...
January 16, 2026 at 6:52 PM
Brian Kennedy, et al. of National University of Singapore report calcium alpha-ketoglutarate (CaAKG), naturally occurring & well studied metabolite linked to healthy aging, can reverse several memory related brain functions disrupted in #Alzheimers Aging Cell👉 onlinelibrary.wiley.com/doi/10.1111/...
An international research effort combining brain imaging and memory testing from thousands of adults is offering a clearer picture of how age-related brain changes affect memory. @andersfjell.bsky.social Learn More in Nature Communications @natureportfolio.nature.com 👉 www.nature.com/articles/s41...
January 14, 2026 at 6:54 PM
An international research effort combining brain imaging and memory testing from thousands of adults is offering a clearer picture of how age-related brain changes affect memory. @andersfjell.bsky.social Learn More in Nature Communications @natureportfolio.nature.com 👉 www.nature.com/articles/s41...
Researchers Xingyu Su, et al. at Waseda University sought to determine if elevated levels of bone morphogenetic proteins, or BMPs, in brains of #AlzheimersDisease patients are assoc w/ impaired neurogenesis & play a role in sex differences observed in AD. Learn More link.springer.com/article/10.1...
January 12, 2026 at 2:58 PM
Researchers Xingyu Su, et al. at Waseda University sought to determine if elevated levels of bone morphogenetic proteins, or BMPs, in brains of #AlzheimersDisease patients are assoc w/ impaired neurogenesis & play a role in sex differences observed in AD. Learn More link.springer.com/article/10.1...
Your daily rhythm may matter more for #BrainHealth than previously thought. Research by Wendy Wang, et al. points to the body clock as possible early warning sign for cognitive decline. @aanbrainhealth.bsky.social 👉 www.neurology.org/doi/10.1212/... ScienceDaily👉 www.sciencedaily.com/releases/202...
January 8, 2026 at 1:54 PM
Your daily rhythm may matter more for #BrainHealth than previously thought. Research by Wendy Wang, et al. points to the body clock as possible early warning sign for cognitive decline. @aanbrainhealth.bsky.social 👉 www.neurology.org/doi/10.1212/... ScienceDaily👉 www.sciencedaily.com/releases/202...
Here, Cleveland Clinic's Noah Lorincz-Comi & Feixiong Cheng introduce a general Bayesian method which returns posterior probabilities that a gene is only assoc w/ #Alzheimers or additionally assoc w/ other phenotypes @alzdemjournals.bsky.social 👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
January 6, 2026 at 4:09 PM
Here, Cleveland Clinic's Noah Lorincz-Comi & Feixiong Cheng introduce a general Bayesian method which returns posterior probabilities that a gene is only assoc w/ #Alzheimers or additionally assoc w/ other phenotypes @alzdemjournals.bsky.social 👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Lindsay Farrer, et al. @bumedicine.bsky.social, studying #Alzheimers in African Americans, have uncovered a striking genetic clue that may cut across racial lines and open the door to new treatment strategies. @alzassociation.bsky.social 👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
January 2, 2026 at 8:32 PM
Lindsay Farrer, et al. @bumedicine.bsky.social, studying #Alzheimers in African Americans, have uncovered a striking genetic clue that may cut across racial lines and open the door to new treatment strategies. @alzassociation.bsky.social 👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
May the New Year bring you joy, happiness, peace and good health! 🎉
December 31, 2025 at 9:44 PM
May the New Year bring you joy, happiness, peace and good health! 🎉
Experimental drug dvlpd @nufeinbergmed.bsky.social has demonstrated promise as early intervention for #Alzheimers. CHECK OUT: Identification of a glia-associated amyloid β oligomer subtype & the rescue from reactive astrogliosis by inhibitor NU-9👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
December 29, 2025 at 7:08 PM
Experimental drug dvlpd @nufeinbergmed.bsky.social has demonstrated promise as early intervention for #Alzheimers. CHECK OUT: Identification of a glia-associated amyloid β oligomer subtype & the rescue from reactive astrogliosis by inhibitor NU-9👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Experimental drug developed by researchers Daniel Kranz, William Klein, et al. @nufeinbergmed.bsky.social has shown further promise as an early intervention for #AlzheimersDisease. Learn More in #Alzheimers & #Dementia @alzassociation.bsky.social
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
December 26, 2025 at 3:15 PM
Experimental drug developed by researchers Daniel Kranz, William Klein, et al. @nufeinbergmed.bsky.social has shown further promise as an early intervention for #AlzheimersDisease. Learn More in #Alzheimers & #Dementia @alzassociation.bsky.social
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
The #PasinettiLab’s family wishes you and your loved ones an AMAZING HOLIDAY filled with #Peace, #Joy, #Love and #Happiness! Most importantly, we wish you the best of HEALTH. Please #StaySafe as you gather for holiday festivities.
December 23, 2025 at 6:10 PM
The #PasinettiLab’s family wishes you and your loved ones an AMAZING HOLIDAY filled with #Peace, #Joy, #Love and #Happiness! Most importantly, we wish you the best of HEALTH. Please #StaySafe as you gather for holiday festivities.
Researchers Huntington Potter, et al. @cuanschutz.bsky.social discovered while brain neuron changes may begin in early life, sargramostim might be repurposed to slow damage, offering new hope for those w/ #Alzheimers & other cognition issues @cp-cellreports.bsky.social
www.cell.com/cell-reports...
www.cell.com/cell-reports...
December 23, 2025 at 3:56 PM
Researchers Huntington Potter, et al. @cuanschutz.bsky.social discovered while brain neuron changes may begin in early life, sargramostim might be repurposed to slow damage, offering new hope for those w/ #Alzheimers & other cognition issues @cp-cellreports.bsky.social
www.cell.com/cell-reports...
www.cell.com/cell-reports...
IN CASE YOU'VE MISSED IT, the #PasinettiLab is excited to share that its new manuscript, "Role of dietary polyphenols in NAD+-dependent deacetylase SIRT 1 in stress-induced depression", is OUT NOW in Molecular Neurobiology. CHECK IT OUT 👉 link.springer.com/article/10.1...
December 22, 2025 at 1:31 PM
IN CASE YOU'VE MISSED IT, the #PasinettiLab is excited to share that its new manuscript, "Role of dietary polyphenols in NAD+-dependent deacetylase SIRT 1 in stress-induced depression", is OUT NOW in Molecular Neurobiology. CHECK IT OUT 👉 link.springer.com/article/10.1...
NEW RESEARCH from Jo Mhairi Hale, et al. 👉 Disentangling #SocialIsolation, #Loneliness & later-life cognitive function for older adults in United States: Evidence from causal inference modeling. @uniofstandrews.bsky.social @emoryuniversity.bsky.social FULL STUDY ➡️ academic.oup.com/psychsocgero...
December 18, 2025 at 2:44 PM
NEW RESEARCH from Jo Mhairi Hale, et al. 👉 Disentangling #SocialIsolation, #Loneliness & later-life cognitive function for older adults in United States: Evidence from causal inference modeling. @uniofstandrews.bsky.social @emoryuniversity.bsky.social FULL STUDY ➡️ academic.oup.com/psychsocgero...
The #PasinettiLab is excited to share its REVIEW "Role of dietary polyphenols in NAD+-dependent deacetylase SIRT 1 in stress-induced depression" ➡️ OUT NOW in Molecular Neurobiology👉 link.springer.com/article/10.1...
@mountsinainyc.bsky.social @ufabcoficial.bsky.social @deptvetaffairs.bsky.social
@mountsinainyc.bsky.social @ufabcoficial.bsky.social @deptvetaffairs.bsky.social
December 17, 2025 at 4:24 PM
The #PasinettiLab is excited to share its REVIEW "Role of dietary polyphenols in NAD+-dependent deacetylase SIRT 1 in stress-induced depression" ➡️ OUT NOW in Molecular Neurobiology👉 link.springer.com/article/10.1...
@mountsinainyc.bsky.social @ufabcoficial.bsky.social @deptvetaffairs.bsky.social
@mountsinainyc.bsky.social @ufabcoficial.bsky.social @deptvetaffairs.bsky.social
Society for Brain Mapping & Therapeutics's 23rd Annual Neurotech Conference is COMING UP FAST🚀 Looking forward to connecting w/ Rudolph Castellani, George Perry & Christopher Wheeler to discuss latest #Neurotech innovations in #Alzheimers & #Dementia. JOIN US! Register Now👉 www.worldBrainMapping.org
December 17, 2025 at 2:45 PM
Society for Brain Mapping & Therapeutics's 23rd Annual Neurotech Conference is COMING UP FAST🚀 Looking forward to connecting w/ Rudolph Castellani, George Perry & Christopher Wheeler to discuss latest #Neurotech innovations in #Alzheimers & #Dementia. JOIN US! Register Now👉 www.worldBrainMapping.org
Researchers Cyrus Raji, et al. @washumedmir.bsky.social have conducted 1st study evaluating impact of #Obesity on #Alzheimers blood #Biomarkers. BBM values increased up to 95% faster in individuals w/ obesity vs. non-obese individuals. Learn More @rsnasky.bsky.social 👉 www.rsna.org/media/press/...
December 10, 2025 at 10:11 PM
Researchers Cyrus Raji, et al. @washumedmir.bsky.social have conducted 1st study evaluating impact of #Obesity on #Alzheimers blood #Biomarkers. BBM values increased up to 95% faster in individuals w/ obesity vs. non-obese individuals. Learn More @rsnasky.bsky.social 👉 www.rsna.org/media/press/...
Why do neurons die in #Dementia & can this process be slowed down? Study by researchers Svenja Lorenz, Marcus Conrad, et al. provides the first molecular evidence that #Ferroptosis can drive #Neurodegeneration in the human brain. Learn More @cellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
December 5, 2025 at 6:19 PM
Why do neurons die in #Dementia & can this process be slowed down? Study by researchers Svenja Lorenz, Marcus Conrad, et al. provides the first molecular evidence that #Ferroptosis can drive #Neurodegeneration in the human brain. Learn More @cellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Large population analysis by Min Xie, Pascal Geldsetzer, et al. @stanforduniversity.bsky.social strengthens growing evidence that viral infections may play an important and previously underappreciated role in #NeurodegenerativeDisease. Learn More @cellpress.bsky.social 👉 www.cell.com/cell/fulltex...
December 3, 2025 at 1:41 PM
Large population analysis by Min Xie, Pascal Geldsetzer, et al. @stanforduniversity.bsky.social strengthens growing evidence that viral infections may play an important and previously underappreciated role in #NeurodegenerativeDisease. Learn More @cellpress.bsky.social 👉 www.cell.com/cell/fulltex...