Martin Götte
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Martin Götte
@gotteprof.bsky.social
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Molecular Cell Biologist focussing on Cancer and Endometriosis research.
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Impact of #SARSCoV2 on the nervous system

www.sciencedirect.com/science/arti...

journals.viamedica.pl/neurologia_n...

journals.asm.org/doi/full/10....
The mechanisms of SARS-CoV-2 initiate coagulation cascades. SARS-CoV-2 can induce a cytokine storm, among them, IL-6 with the IL-6 receptor complexes, and IL-1ß can bind to platelets and over-activate platelets. SARS-CoV-2 can increase heparanase activity. Also, heparanase can cleave the heparan sulfate proteoglycan, thus releasing the coagulation factor. Heparanase induces the expression of tissue factors which initiates blood coagulation. Brain gut axis Infection leading to cerebral endothelial dysfunction and damage Mitochondrial in nerve cells Anaerobic metabolism
January 4, 2025 at 4:55 AM