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grantpellowe.bsky.social
Grant Pellowe
@grantpellowe.bsky.social
310 followers 980 following 3 posts
Research fellow at Aston Institute of Membrane Excellence. Previously folding proteins at The Crick and membrane proteins at King's College London.
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Reposted by Grant Pellowe
natsmb.nature.com
Nature Structural & Molecular Biology @natsmb.nature.com · 20d
New online: The human ribosome modulates multidomain protein biogenesis by delaying cotranslational domain docking
The human ribosome modulates multidomain protein biogenesis by delaying cotranslational domain docking
Nature Structural & Molecular Biology, Published online: 19 September 2025; doi:10.1038/s41594-025-01676-5By studying dynamic folding intermediates on the human ribosome, Pellowe et al. show that newly made domains help each other to fold but do not stably interact until synthesis is complete, avoiding interdomain misfolding.
go.nature.com
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grantpellowe.bsky.social
Grant Pellowe @grantpellowe.bsky.social · May 28
Re-advertising! Closes September 1st.

💧 Interested in understanding how Aquaporins fold into membranes as they're being synthesised? 💧

If so, come and do your PhD with me, @kitchenphil.bsky.social and @roslynbill.bsky.social at @astonaime.bsky.social

tinyurl.com/5dc23mu3

Reach out for details!
Delineating stages of Aquaporin biogenesis at Aston University on FindAPhD.com
PhD Project - Delineating stages of Aquaporin biogenesis at Aston University, listed on FindAPhD.com
tinyurl.com
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grantpellowe.bsky.social
Grant Pellowe @grantpellowe.bsky.social · Mar 31
1 week to go - get your applications in!
grantpellowe.bsky.social
Grant Pellowe @grantpellowe.bsky.social · Feb 24
💧 Are you interested in understanding how Aquaporins fold into membranes as they're being synthesised? 💧

If so, come and do your PhD with me, @kitchenphil.bsky.social and @roslynbill.bsky.social at @astonaime.bsky.social!

www.findaphd.com/phds/project...

Reach out for further details!
Delineating stages of Aquaporin biogenesis at Aston University on FindAPhD.com
PhD Project - Delineating stages of Aquaporin biogenesis at Aston University, listed on FindAPhD.com
www.findaphd.com
Reposted by Grant Pellowe
biorxiv-biochem.bsky.social
bioRxiv Biochemistry @biorxiv-biochem.bsky.social · Sep 20
The human ribosome modulates multidomain protein biogenesis by delaying cotranslational domain docking https://www.biorxiv.org/content/10.1101/2024.09.19.613857v1
The human ribosome modulates multidomain protein biogenesis by delaying cotranslational domain docking https://www.biorxiv.org/content/10.1101/2024.09.19.613857v1
Proteins with multiple domains are intrinsically prone to misfold, yet fold efficiently during their
www.biorxiv.org
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grantpellowe.bsky.social
Grant Pellowe @grantpellowe.bsky.social · Feb 24
💧 Are you interested in understanding how Aquaporins fold into membranes as they're being synthesised? 💧

If so, come and do your PhD with me, @kitchenphil.bsky.social and @roslynbill.bsky.social at @astonaime.bsky.social!

www.findaphd.com/phds/project...

Reach out for further details!
Delineating stages of Aquaporin biogenesis at Aston University on FindAPhD.com
PhD Project - Delineating stages of Aquaporin biogenesis at Aston University, listed on FindAPhD.com
www.findaphd.com
1 6