Grisha
@grisha-8.bsky.social
Postdoc currently working on cell biology in ALS and FTD. Study the pathogenicity of TDP-43 fibrils.
Reposted by Grisha
Proximity labeling users: check out this study by @zhixingchen2.bsky.social and Peng Zou, which establishes how much contact-dependence vs. diffusion is responsible for biotinylation — tl;dr TurboID has a much smaller effective radius! www.nature.com/articles/s41... 1/2
Spatial barcoding reveals reaction radii and contact-dependent mechanism of proximity labeling - Nature Chemical Biology
A DNA nanoruler platform enables precise measurement of the labeling radii of TurboID and APEX2, uncovering their contact-dependent mechanisms. These findings redefine the enzymology of proximity labe...
www.nature.com
December 31, 2025 at 5:53 PM
Proximity labeling users: check out this study by @zhixingchen2.bsky.social and Peng Zou, which establishes how much contact-dependence vs. diffusion is responsible for biotinylation — tl;dr TurboID has a much smaller effective radius! www.nature.com/articles/s41... 1/2
Reposted by Grisha
Tu Youyou discovered artemisinin, a drug therapy for #malaria that has saved millions of lives. She was born #OTD. 🧪 ow.ly/D8WO30mlgJs #LaskerLaureate
December 30, 2025 at 2:02 PM
Tu Youyou discovered artemisinin, a drug therapy for #malaria that has saved millions of lives. She was born #OTD. 🧪 ow.ly/D8WO30mlgJs #LaskerLaureate