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gsbardella.bsky.social @gsbardella.bsky.social · 8d

Join @youngscinet.bsky.social for "Under Pressure: A Mental Health Conversation for the Academic Community," a virtual workshop aimed at building resilience, support and creating a healthier future for yourself and academia.
October 10 - 1PM
🔗 us06web.zoom.us/webinar/regi...

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EFMC @euromedchem.bsky.social · Aug 27

👩‍🔬 Have you read our latest #MedChemBioConversation ?

Get to know Maria Letizia Barreca from University of Perugia, Italy.🔍
Dive into our monthly talks with specialists to explore the latest breakthroughs in drug discovery and pick up some valuable advice.

🔗https://buff.ly/63Jy5As

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gsbardella.bsky.social @gsbardella.bsky.social · Aug 27

(I had to repost this since the BlueSky account named DPhG is not related to DPhG…)

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gsbardella.bsky.social @gsbardella.bsky.social · Aug 27

The report of the FiMC, co-organized by the Med Chem Division of the @gdch.de, the #DPhG and the @scs-dmccb.bsky.social, has been just published in #ChemMedChem (@chemistryeurope.bsky.social)

chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

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gsbardella.bsky.social @gsbardella.bsky.social · Aug 27

A new
#ChemMedChem (@chemistryeurope.bsky.social) article explores the effect of modified bifunctional antisense oligonucleotides (BASOs) on the phenotype of cancer cells, evaluated by real-time measurement of cell proliferation and motility. chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

Modified Nucleotides in Bifunctional Antisense Oligonucleotides: Exploring their Anticancer Potential

bifunctional antisense oligonucleotide (BASO) modulates pre-mRNA splicing by using two functional domains: an antisense region that hybridizes with target sequences and a regulatory region that recru...

chemistry-europe.onlinelibrary.wiley.com

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gsbardella.bsky.social @gsbardella.bsky.social · Aug 26

The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out (chemistry-europe.onlinelibrary.wiley.com/toc/18607187...) with a Front Cover illustrating the crystal structure of the N-terminal domain of clathrin with the known binding sites colored and a selection of Pitstop 2 analogues.

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gsbardella.bsky.social @gsbardella.bsky.social · Jun 21

An Highlight article just accepted in #ChemMedChem (@chemistryeurope.bsky.social) spotlights #balinatunfib, an orally available small molecule jointly developed by Sanofi and UCB preventing TNFα from effectively binding to its receptors.

chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

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gsbardella.bsky.social @gsbardella.bsky.social · Jun 18

The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out (chemistry-europe.onlinelibrary.wiley.com/toc/18607187...)!

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Reposted by gsbardella.bsky.social

Stu Cantrill @stuartcantrill.com · Jun 16

I have poked the @rsc.org on X/Twitter a bit over the years (sorry folks...), but huge kudos to them for leaving what has become even more of a toxic and hateful platform www.rsc.org/news-events/... 👏 #chemsky

Social media and connecting with our community

www.rsc.org

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Reposted by gsbardella.bsky.social

Stephan Hacker @stephanhacker2.bsky.social · Jun 17

Only two weeks left to apply for a Flash Talk at the 5th Virtual @chembiotalks.bsky.social!

If you are a PhD or postdoc and want a chance to present to a global #ChemBio audience, make sure to check out our abstract challenge: chemistry-europe.onlinelibrary.wiley.com/hub/journal/...

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gsbardella.bsky.social @gsbardella.bsky.social · Jun 17

Another great edition of @youngscinet.bsky.social #MedChemBioOnline is going to start in 1 hour and a half. Do not miss the opportunity to learn about "Best Practices in Discovering PROTACs" with experts in the field!

EFMC Young Scientists Network @youngscinet.bsky.social · Jun 5

Swipe to discover our speakers!

Join us in 2 weeks for the 21st EFMC-YSN MedChemBioOnline on June 17, 2025, from 15:30 to 17:30 CET. Learn about “Best Practices in Discovering PROTACs” with experts.

💻 Online via Zoom
🔗 Free, but registration is mandatory

Thanks to our sponsor Advion.

gsbardella.bsky.social @gsbardella.bsky.social · May 21

The last talk of the day at the 11th Novalix Conference “Biophysics in Drug Discovery” was the terrific keynote lecture by Stefan Knapp on "Comprehensive Characterization of Chemical Tools and New Modalities such as PROTACs".
@thesgc.bsky.social

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gsbardella.bsky.social @gsbardella.bsky.social · May 21

Amazing keynote lecture by Amanda Garner at the 11th Novalix Conference—Biophysics in Drug Discovery in Strasbourg.

Amanda delivered a brilliant talk on "Enabling Technologies for Revealing Druggable Paths in RNA Biology".
@acsmedi.bsky.social

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gsbardella.bsky.social @gsbardella.bsky.social · May 21

Great talk by @mariaduca-cnrs.bsky.social at the 11th Novalix Conference about Biophysics in Drug Discovery. Maria presented a few of her group projects, talking on how to target RNA using synthetic small molecules and how to discover an characterize RNA binders. Brilliant!

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gsbardella.bsky.social @gsbardella.bsky.social · May 21

The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out!

chemistry-europe.onlinelibrary.wiley.com/toc/18607187...

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Reposted by gsbardella.bsky.social

Derek Lowe @dereklowe.bsky.social · Apr 2

No orders for supplies/reagents/equipment (already a huge bottleneck after earlier cuts). No travel or conference registrations. And certainly no hiring.

So this could be a total freeze, in everything but name. Is that the new workaround the administration is trying? Isn't that illegal? (2/2)

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Reposted by gsbardella.bsky.social

Derek Lowe @dereklowe.bsky.social · Apr 2

I'm getting word that the latest attempt to strangle what's left of the NIH is that purchasing agents have been mostly/completely cut, with the purchasing to be done by centralized GSA staff. Who either don't exist or aren't assigned.

That means in practice no spending at all! (1/2)

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Bethany Halford @bethanyhalford.bsky.social · Mar 28

If you love drug candidates but weren't able to attend the #FirstTimeDisclosures symposium at #ACSSpring2025, check out my story about the session for @cenmag.bsky.social - with lots of cool-looking molecules.
cen.acs.org/acs-news/acs...

12 drug candidates debut in San Diego

Structures unveiled during first-time disclosures symposium

cen.acs.org

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gsbardella.bsky.social @gsbardella.bsky.social · Mar 25

Absolutely my pleasure! Looking forward to meeting you again in Rome in late November for the Avogadro Colloquia of the @socchimita.bsky.social

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gsbardella.bsky.social @gsbardella.bsky.social · Mar 24

An amazing, totally inspirational and emotional journey! The @acs.org Priestley Medal talk by @francesarnold.bsky.social at #ACSSpring2025

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gsbardella.bsky.social @gsbardella.bsky.social · Mar 9

The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out!

chemistry-europe.onlinelibrary.wiley.com/toc/18607187...

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Reposted by gsbardella.bsky.social

Martin Enserink @martinenserink.bsky.social · Feb 27

New on @science.org's daily Trump Tracker: A key influenza vaccine meeting gets abruptly canceled, and more than 90% of all USAID grants are terminated.
www.science.org/content/arti...

Trump Tracker: Firings, lawsuits, and U.S. science in chaos

Follow President Donald Trump’s impact on U.S. research and science globally

www.science.org

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Reposted by gsbardella.bsky.social

Science Magazine @science.org · Feb 27

A new White House freeze on using government-issued credit cards is the latest shock for federal scientists, potentially affecting everything from conference travel to needed purchases for clinical care or lab work. scim.ag/4hV9oRb

Trump credit card freeze sparks alarm at health agencies

“Cost efficiency” order could block travel, supplies for labs and patient care

scim.ag

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gsbardella.bsky.social @gsbardella.bsky.social · Feb 27

A Career doing STUFF, a Guest Editorial by Mike Hann for the #ChemMedChem (@chemistryeurope.bsky.social) MedChem Musings series, summarises the many things he did during his 45 year-career in drug discovery. Practical advices and inspiration for future generations of researchers.

lnkd.in/dNNy7FaE

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