Haikuo Li
Haikuo Li
@haikuoli.bsky.social
Postdoc Yale | PhD WashU | BS SJTU | Interested in single-cell & spatial omics, epigenetics & genome science
Reposted by Haikuo Li
A new spatial transcriptomics approach eliminates the need for time-intensive imaging with specialized equipment, making the technique accessible to more researchers around the world. @naturebiotech.bsky.social
Scientists have developed a way to scale up spatial genomics and lower costs
A new computational approach eliminates time-intensive imaging, enabling high-resolution spatial mapping of gene expression in tissue.
broad.io
April 3, 2025 at 1:14 PM
Reposted by Haikuo Li
#NewNProt: Protocol Extension describing joint spatially resolved epigenomic and transcriptomic profiling on a tissue section using #microfluidic chips bit.ly/4hLs7xT #spatialtranscriptomics #spatialepigenomics see also associated News & Views
Spatially resolved genome-wide joint profiling of epigenome and transcriptome with spatial-ATAC-RNA-seq and spatial-CUT&Tag-RNA-seq - Nature Protocols
In this Protocol Extension, the authors describe procedures for spatial barcoding in tissue sections using a microfluidic chip followed by sequencing-based joint genome-wide profiling of transcriptome...
bit.ly
March 27, 2025 at 9:47 AM
Reposted by Haikuo Li
Biological systems find ingenuous solutions. Almost anything that can happen, happens.

Still, I would not have guessed a role of RNA-binding proteins on the cell surface.

@raflynn5.bsky.social and his team are boldly investigating glycoRNAs and following their leads.
February 27, 2025 at 4:33 PM