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Hana Hanzlikova @hanzlikovalab.bsky.social · Jul 28

Our latest study is out in Nucleic Acids Research. FEN1 is critical for rapid single-strand break repair in G1 phase url: academic.oup.com/nar/article/...

FEN1 is critical for rapid single-strand break repair in G1 phase

Abstract. Flap endonuclease 1 (FEN1)-dependent long-patch repair has been considered a minor sub-pathway of DNA single-strand break repair (SSBR), activate

academic.oup.com

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Hana Hanzlikova @hanzlikovalab.bsky.social · Jun 20

Truly honoured to write about this brilliant work. Huge credit to Bea!

Apoorva Baluapuri @baluapuri.bsky.social · Jun 20

Much appreciate the spotlight on our (‪@adelmanlab.bsky.social‬) paper about INT depletion/dsRNA-induced stress responses by @hanzlikovalab.bsky.social Amazing to see the finding being placed in perspective of the big picture of neurodevelopmental diseases and therapeutic targets 🙏 #RNABiology

Molecular Cell @cp-molcell.bsky.social · Jun 20

Integrator complex collapse: A mechanistic route to integrated stress response and disease

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Reposted by Hana Hanzlikova

Apoorva Baluapuri @baluapuri.bsky.social · Jun 20

Much appreciate the spotlight on our (‪@adelmanlab.bsky.social‬) paper about INT depletion/dsRNA-induced stress responses by @hanzlikovalab.bsky.social Amazing to see the finding being placed in perspective of the big picture of neurodevelopmental diseases and therapeutic targets 🙏 #RNABiology

Molecular Cell @cp-molcell.bsky.social · Jun 20

Integrator complex collapse: A mechanistic route to integrated stress response and disease

In a recent Cell article, Baluapuri et al. show that loss of the Integrator (INT) complex activates the integrated stress response via double-stranded RNA from incomplete pre-mRNAs, revealing a link to INT-related neurodevelopmental diseases and potential therapeutic targets.

dlvr.it

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Reposted by Hana Hanzlikova

Lopes_Lab @lopeslab.bsky.social · May 7

Exciting PhD project available in our lab (time sensitive)! 👇

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Hana Hanzlikova @hanzlikovalab.bsky.social · Apr 1

To je, co z tiskové zprávy AVČR udělá ČTK… jsem si jistá, že Leoš tohle ani neviděl ani nemohl ovlivnit…

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Reposted by Hana Hanzlikova

Oded Rechavi @odedrechavi.bsky.social · Apr 1

Who does that? We rented a train JUST for the conference, that will take the participants from Prague to the woods of Bohemia. There'll be talks ON THE TRAIN. In Prague we'll have 5 locations with different atmospheres.
#theconferencetoendallconferences Register now:
woodstock.img.cas.cz

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Reposted by Hana Hanzlikova

Lopes_Lab @lopeslab.bsky.social · Mar 17

Exciting seminar series from Genome integrity italian Network (GiiN), chaired by myself and Raffaella Di Micco! Short talks (2x30’), at convenient time for EU/USA attendees. Big shots and raising stars in an expanding field. See flyers + link to receive email alerts. Please repost to your network!👇

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Reposted by Hana Hanzlikova

Petr Svoboda @svobodalab.bsky.social · Mar 1

#theconferencetoendallconferences
woodstock.img.cas.cz
The website is up & registration is open!

three men in armor are standing next to each other with the words and so it begins below them

ALT: three men in armor are standing next to each other with the words and so it begins below them

media.tenor.com

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Reposted by Hana Hanzlikova

Institute of Molecular Genetics @imgprague.bsky.social · Feb 10

❗WE ARE HIRING - POSTDOC WANTED in the Laboratory of Genome Dynamics @hanzlikovalab.bsky.social
👉https://www.img.cas.cz/group/hana-hanzlikova/

Join a dynamic, international, and multidisciplinary team with an open-door policy for idea exchange, experimental troubleshooting, and shared success.

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Reposted by Hana Hanzlikova

Anja Groth @groth-anja.bsky.social · Feb 26

SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.

Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).

www.embl.org/about/info/c...

DNA replication and genome maintenance: from basic biology to disease

www.embl.org

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Hana Hanzlikova @hanzlikovalab.bsky.social · Feb 13

Great to have Bea as part of our team!

Institute of Molecular Genetics @imgprague.bsky.social · Feb 13

💜🔬Join Beatrice in the Laboratory of Genome Dynamics @hanzlikovalab.bsky.social.
Learn more about our PhD projects 👉http://img.cas.cz/phd
Join us, we are waiting for you!
Your future starts now!
#phd #phdstudent #science #openpositions #phdcommunity #prague

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Hana Hanzlikova @hanzlikovalab.bsky.social · Feb 6

📢 We also have an open postdoctoral position available!

www.img.cas.cz/2025/02/8508...

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Reposted by Hana Hanzlikova

Institute of Molecular Genetics @imgprague.bsky.social · Feb 5

✨Wondering how it looks at IMG? Come and find out!
Learn more about our PhD projects 👉http://img.cas.cz/phd
Join us, we are waiting for you!
Your future starts now!
#phd #phdstudent #science #openpositions #phdcommunity
#prague

www.youtube.com/watch?v=FucH...

Promotional video (short version) - Institute of Molecular Genetics of the Czech Academy of Sciences

YouTube video by Institute of Molecular Genetics

www.youtube.com

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Reposted by Hana Hanzlikova

Sarah Lambert's Lab @lambertsarahlab.bsky.social · Jan 4

Please RT. Join the sixth edition of our Training Unit @institut_curie
international course on Genome Instability & Human Disease open to master students, PhDs and researchers! Amazing program. Registration dead line 2nd March 2025 at training.institut-curie.org/courses/geno...

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Hana Hanzlikova @hanzlikovalab.bsky.social · Feb 4

🧬🔊 We’re looking for a PhD student who’s ready to make discoveries!

Institute of Molecular Genetics @imgprague.bsky.social · Jan 17

🔬Join Laboratory of Genome Dynamics and study brain structures with @hanzlikovalab.bsky.social
Learn more about the project 👉img.cas.cz/phd
Join us, we are waiting for you!
Your future starts now!

📸Kristýna Hrychová and Beatrice Valtorta

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Hana Hanzlikova @hanzlikovalab.bsky.social · Jan 22

Congratulations! Everything is possible..

Petr Svoboda @svobodalab.bsky.social · Jan 21

1/n So, this is out in NAR, finally. The longest, the most expensive and the most challenging project in the lab. Sparked by controversy concerning mammalian antiviral RNAi and our identification of Dicer variant, which is sufficient to increase RNAi.
doi.org/10.1093/nar/...

Enhanced RNAi does not provide efficient innate antiviral immunity in mice

Abstract. In RNA interference (RNAi), long double-stranded RNA is cleaved by the Dicer endonuclease into small interfering RNAs (siRNAs), which guide degra

doi.org

Hana Hanzlikova @hanzlikovalab.bsky.social · Jan 16

An opening is also available in our group. We are looking forward to recruiting an enthusiastic scientist!

Institute of Molecular Genetics @imgprague.bsky.social · Jan 16

🚀Boost your scientific career with us!
See all open positions 👉 img.cas.cz/phd
Join us, we are waiting for you!
Your future starts now!

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Hana Hanzlikova @hanzlikovalab.bsky.social · Jan 14

FEBS Registration open! Youth Travel Fund Grants deadline 16th February 2025 - An engaging gathering to connect with the PARP community parp2025.febsevents.org/speakers

FEBS Advanced Lecture Course 2025 – PARP2025: from molecular aspects to medical applications<br /> - Plenary Speakers

Plenary Speakers for the Proteases and biological course. Plenary Speakers for the Proteases and biological course.

parp2025.febsevents.org

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