@harveyhippolab.bsky.social
Reposted
Targeting the Hippo pathway in cancer www.nature.com/articles/s41...
rdcu.be/et8aj
This new Review discusses emerging Hippo pathway-targeted therapies for cancer, particularly those that target TEAD DNA binding proteins and their interaction with the YAP/TAZ transcription co-activators
rdcu.be/et8aj
This new Review discusses emerging Hippo pathway-targeted therapies for cancer, particularly those that target TEAD DNA binding proteins and their interaction with the YAP/TAZ transcription co-activators
June 30, 2025 at 2:26 PM
Targeting the Hippo pathway in cancer www.nature.com/articles/s41...
rdcu.be/et8aj
This new Review discusses emerging Hippo pathway-targeted therapies for cancer, particularly those that target TEAD DNA binding proteins and their interaction with the YAP/TAZ transcription co-activators
rdcu.be/et8aj
This new Review discusses emerging Hippo pathway-targeted therapies for cancer, particularly those that target TEAD DNA binding proteins and their interaction with the YAP/TAZ transcription co-activators
Pleased to share our review in @natrevdrugdiscov.nature.com. 20+ years after the Hippo pathway was discovered in Drosophila, the first targeted therapies are in clinical trials for cancer and heart disease.
Big thanks to co-author Tracy Tang from Vivace Therapeutics. #TEADinhibitors
rdcu.be/et2NL
Big thanks to co-author Tracy Tang from Vivace Therapeutics. #TEADinhibitors
rdcu.be/et2NL
Targeting the Hippo pathway in cancer
Nature Reviews Drug Discovery - The Hippo signalling pathway fulfils a vital role in the regulation of tissue homeostasis and organ development and its dysregulation is associated with several...
rdcu.be
July 2, 2025 at 11:50 PM
Pleased to share our review in @natrevdrugdiscov.nature.com. 20+ years after the Hippo pathway was discovered in Drosophila, the first targeted therapies are in clinical trials for cancer and heart disease.
Big thanks to co-author Tracy Tang from Vivace Therapeutics. #TEADinhibitors
rdcu.be/et2NL
Big thanks to co-author Tracy Tang from Vivace Therapeutics. #TEADinhibitors
rdcu.be/et2NL