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The Hassan Brain Development Team @hassanbraindevlab.bsky.social · 5d

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The Hassan Brain Development Team @hassanbraindevlab.bsky.social · 16d

Latest from the lab: the immensely talented Johnny Bou Rouphael and Laila El Khattabi in the team report the discovery and functional analysis defective splicing in a human developmental disorder. www.linkedin.com/posts/bassem...

Heterozygous pathogenic variants in the splicing factor SF1 lead to a large spectrum of neurodevelopmental disorders | Bassem Hassan

Latest from the lab: the immensely talented Johnny Bou Rouphael and Laila El Khattabi in the team report the discovery and functional analysis defective splicing in a human developmental disorder.

www.linkedin.com

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The Hassan Brain Development Team @hassanbraindevlab.bsky.social · 16d

For those who understand Arabic 😊
A podcast about @bassemh.bsky.social work and career. Thank you Haifa Alhadyian, PhD for this amazing initiative.

www.linkedin.com/posts/activi...

الحلقة الأولى من بودكاست "مقابلات مع علماء عرب حول العالم" متاحه للإستماع الآن 🎙️ 🧠 🔬 .. ضيفي للحلقة الأولى هو الدكتور باسم حسن (Bassem Hassan)، قائد فريق في معهد باريس للدماغ في فرنسا في ...

الحلقة الأولى من بودكاست "مقابلات مع علماء عرب حول العالم" متاحه للإستماع الآن 🎙️ 🧠 🔬 .. ضيفي للحلقة الأولى هو الدكتور باسم حسن (Bassem Hassan)، قائد فريق في معهد باريس للدماغ في فرنسا في تخصص علم ا...

www.linkedin.com

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Reposted by The Hassan Brain Development Team

Iryna Mohylyak @mohylyak.bsky.social · 22d

Excited to share our latest paper in Nature Communications! We uncovered a dev-time transcriptional program (via Mirana → Pink1) that shapes mitochondria & circuit wiring.
Disrupt it early, and neurons miswire — even if the gene recovers later!

The Hassan Brain Development Team @hassanbraindevlab.bsky.social · Sep 1

Latest from the lab, the beautiful work of Iryna Mohylyak and colleagues describing a temporal developmental transcriptional program for mitochondrial quality control and synaptic connectivity, with @jdejuan-sanz.bsky.social, Olga Corti and @steinaerts.bsky.social
labs
www.nature.com/articles/s41...

Temporal transcriptional regulation of mitochondrial morphology primes activity-dependent circuit connectivity - Nature Communications

This study investigates the developmental transcriptional regulation of mitochondrial quality control. Authors identify the Drosophila factor Mirana, homologous to mammalian TZAP, as a key temporal re...

www.nature.com

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The Hassan Brain Development Team @hassanbraindevlab.bsky.social · 27d

Registration is now open for 2026 GRC on Neural Development
@neuraldevgrc.bsky.social
Register early because places go fast!

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The Hassan Brain Development Team @hassanbraindevlab.bsky.social · Sep 1

Latest from the lab, the beautiful work of Iryna Mohylyak and colleagues describing a temporal developmental transcriptional program for mitochondrial quality control and synaptic connectivity, with @jdejuan-sanz.bsky.social, Olga Corti and @steinaerts.bsky.social
labs
www.nature.com/articles/s41...

Temporal transcriptional regulation of mitochondrial morphology primes activity-dependent circuit connectivity - Nature Communications

This study investigates the developmental transcriptional regulation of mitochondrial quality control. Authors identify the Drosophila factor Mirana, homologous to mammalian TZAP, as a key temporal re...

www.nature.com

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Reposted by The Hassan Brain Development Team

Neural Development GRC 2026 @neuraldevgrc.bsky.social · Jul 14

👋🏻 Bluesky!

Siegenthaler Lab @siegenthalerlab.bsky.social · Jul 14

Bassem Hassan @bassemh.bsky.social, Corey Harwell & yours truly are co-chairs for 2026 Neural Development #GRC August 2-7, 2026 in Newport, RI 🇺🇸 - if you are interested in updates on the conference & to hear about our 🤩 line-up of speakers...follow @neuraldevgrc.bsky.social!
🧠🪰🐭🐙🐸🦎🧒🏻🧫🧪🧠

image of web page for Neural Development GRC - go to https://www.grc.org/neural-development-conference/2026/

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Reposted by The Hassan Brain Development Team

Siegenthaler Lab @siegenthalerlab.bsky.social · Jul 14

Bassem Hassan @bassemh.bsky.social, Corey Harwell & yours truly are co-chairs for 2026 Neural Development #GRC August 2-7, 2026 in Newport, RI 🇺🇸 - if you are interested in updates on the conference & to hear about our 🤩 line-up of speakers...follow @neuraldevgrc.bsky.social!
🧠🪰🐭🐙🐸🦎🧒🏻🧫🧪🧠

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The Hassan Brain Development Team @hassanbraindevlab.bsky.social · Jun 19

Congrats to the fantastic @maheandria.bsky.social on this well deserved recognition from French Academy of Science

maheandria.bsky.social @maheandria.bsky.social · Jun 19

It is a Great Honour to receive the 'Les Grandes Avancées en Biologie' award 🏅 from the @academiesciences.bsky.social and to share our work during this fabulous day celebrating Science. Thank you!
@hassanbraindevlab.bsky.social @institutducerveau.bsky.social @frm-officiel.bsky.social

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Reposted by The Hassan Brain Development Team

maheandria.bsky.social @maheandria.bsky.social · May 7

This journey began in Berlin with @bassemh.bsky.social and Robin Hiesinger, and continued at @institutducerveau.bsky.social in @hassanbraindevlab.bsky.social , with the generous support of @frm-officiel.bsky.social . Grateful to the von Kleist & Stoeckli Labs and all co-authors!

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Reposted by The Hassan Brain Development Team

Nature Neuroscience @natneuro.nature.com · May 7

A temporal sequence of genetically encoded stochastic mechanisms explains variation in stereotyped neuronal circuits in Drosophila 🧪🧠

@bassemh.bsky.social @maheandria.bsky.social @hassanbraindevlab.bsky.social @institutducerveau.bsky.social

www.nature.com/articles/s41...

Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster - Nature Neuroscience

The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in stereotyped neuronal circu...

www.nature.com

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The Hassan Brain Development Team @hassanbraindevlab.bsky.social · May 7

New from the lab: @maheandria.bsky.social and colleagues in collaboration with the Hiesinger, Stoeckli and von Kleist labs dissect the sequential emergence of axonal targeting during development in today's issue of Nature Neuroscience:
rdcu.be/ek010

Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster

Nature Neuroscience - The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in...

rdcu.be

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Reposted by The Hassan Brain Development Team

Bassem Hassan @bassemh.bsky.social · May 7

Hot off the press:
The excellent Maheva Andriatsilavo and colleagues show how a temporal sequence of stochastic molecular mechanisms allow the emergence of stereotyped individualised neuronal circuits. Just published in Nature Neuroscience:
rdcu.be/ek010

Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster

Nature Neuroscience - The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in...

rdcu.be

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The Hassan Brain Development Team @hassanbraindevlab.bsky.social · May 6

👇🏽

Bassem Hassan @bassemh.bsky.social · May 6

@maheandria.bsky.social and I challenge the notion of a static and deterministic definition of a (neural) cell type and argue for its replacement by a multi parametric probabilistic definition in this perspective
sciencedirect.com/science/arti...

Toward a probabilistic definition of neural cell types

A classical view of cell type relies on a definite set of stable properties that are critical for brain functions. Single-cell technologies led to an …

sciencedirect.com

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The Hassan Brain Development Team @hassanbraindevlab.bsky.social · Apr 30

Anna CHRZANOWSKA, PhD, postdoc in The Hassan Brain Development Team
@hassanbraindevlab.bsky.social
is organizing a trainee-led symposium @institutducerveau.bsky.social June 2-4

Spread the word!

nenckiopenlab.org/decoding/

Nencki Open Lab

Decoding the brain: from methods to meaning Paris Brain Institute, June 2-4th 2025 Applying machine learning and other models to decode behavioral parameters from neural activity is now a standard …

nenckiopenlab.org

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Reposted by The Hassan Brain Development Team

Margarete Diaz Cuadros @mdiazcuadros.bsky.social · Dec 20

Can't miss opportunity for anyone interested in developmental timing!! See you in Paris⏳️

Teresa Rayon @trayon.bsky.social · Dec 20

Join us in Paris 6-9 May 2025 for the #EvoDevoTempo conference (2nd edition) with a fantastic line up of speakers confirmed!!

Organized by @mdiazcuadros.bsky.social
@vanderhaeghenp2.bsky.social
@bassemh.bsky.social and me.

Please RT to spread the word

meetings.embo.org/event/25-dev...

Developmental timing across species: From mechanisms to evolutionary insights

Like choreography, development consists of a highly ordered suite of steps and transitions. Modifying developmental tempo can affect final size and composition of tissues, as well as their plasticity…

meetings.embo.org

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Reposted by The Hassan Brain Development Team

Teresa Rayon @trayon.bsky.social · Dec 20

Join us in Paris 6-9 May 2025 for the #EvoDevoTempo conference (2nd edition) with a fantastic line up of speakers confirmed!!

Organized by @mdiazcuadros.bsky.social
@vanderhaeghenp2.bsky.social
@bassemh.bsky.social and me.

Please RT to spread the word

meetings.embo.org/event/25-dev...

Developmental timing across species: From mechanisms to evolutionary insights

Like choreography, development consists of a highly ordered suite of steps and transitions. Modifying developmental tempo can affect final size and composition of tissues, as well as their plasticity…

meetings.embo.org

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Reposted by The Hassan Brain Development Team

Bassem Hassan @bassemh.bsky.social · Dec 20

enews.embo.org?EventID=w25-...

EMBO Workshop on Developmental timing across species: From mechanisms to evolutionary insights

enews.embo.org

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The Hassan Brain Development Team @hassanbraindevlab.bsky.social · Dec 1

Second edition of the EMBO workshop on Developmental Timing across species.
Second edition organized by
@trayon.bsky.social @bassemh.bsky.social @vanderhaeghenp2.bsky.social and Margerete Diaz-Cuadros

Cool speakers & fun networking activities.
More details coming soon.Save the date:
May 6-9 2025!

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The Hassan Brain Development Team @hassanbraindevlab.bsky.social · Nov 25

This is the Blue Sky account of the Hassan Brain Development lab. Let's connect!

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