Helena Stafflinger
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helena-stafflinger.bsky.social
Helena Stafflinger
@helena-stafflinger.bsky.social
PhD student at Wöhnert lab - Goethe University - Frankfurt am Main
Structural biology of RNA and RNA-protein-complexes using X-ray crystallography, NMR and cryo-EM
22nd of December and I already got my first Christmas present 🎁

My first paper has been published in NAR as a Breakthrough article and I’m beyond excited ✨

A big thanks to everyone involved in this project, especially Jens Wöhnert and Hermann Schindelin @en-hxnu-enment.bsky.social !
⭐NAR Breakthrough! ⭐
🧬 A synthetic RNA forms a #G-quadruplex without a G-rich sequence, using a complex 3D fold and GTP as a ligand. This suggests G-quadruplexes may be far more widespread in biologically important RNAs. Read more: doi.org/10.1093/nar/...

#NARBreaktrhough #RNA #StructuralBiology
December 22, 2025 at 5:39 PM
Reposted by Helena Stafflinger
Proud that our work is online now in @jacs.acspublications.org 🎉 A big thanks to everyone involved in this project! If you are interested have a read:

doi.org/10.1021/jacs...
Conformational Plasticity of LptC Regulates Lipopolysaccharide Transport by the LptB2FGC Complex
The outer membrane of Gram-negative bacteria is coated with lipopolysaccharide (LPS). The Lpt system generates membrane asymmetry by transporting LPS from the inner to the outer membrane. Transport be...
doi.org
September 23, 2025 at 5:30 PM