Nucleic Acids Research
@narjournal.bsky.social
Nucleic Acids Research (NAR), from Oxford University Press, publishes the results of leading-edge research into physical, chemical, biochemical and biological aspects of nucleic acids and proteins involved in nucleic acid metabolism and/or interactions
Pinned
Hello Everyone! 👋 Nucleic Acids Research is excited to be on Bluesky! Please follow us for the latest #Research, #Breakthrough articles, journal issues and more. Also, please consider adding us to your starter packs!
⭐NAR Breakthrough! ⭐
🚀 ALE RNA platform overcomes length limits in #chemicaRNAsynthesis, enabling >200-nt RNAs. Supports sgRNAs and 5′-capped mRNAs with strong translation and precise mods. Site-specific 2′-OMe poly(A) boosts protein expression. 🧬Read more: doi.org/10.1093/nar/...
#NARBreakthrough
🚀 ALE RNA platform overcomes length limits in #chemicaRNAsynthesis, enabling >200-nt RNAs. Supports sgRNAs and 5′-capped mRNAs with strong translation and precise mods. Site-specific 2′-OMe poly(A) boosts protein expression. 🧬Read more: doi.org/10.1093/nar/...
#NARBreakthrough
January 19, 2026 at 6:23 PM
⭐NAR Breakthrough! ⭐
🚀 ALE RNA platform overcomes length limits in #chemicaRNAsynthesis, enabling >200-nt RNAs. Supports sgRNAs and 5′-capped mRNAs with strong translation and precise mods. Site-specific 2′-OMe poly(A) boosts protein expression. 🧬Read more: doi.org/10.1093/nar/...
#NARBreakthrough
🚀 ALE RNA platform overcomes length limits in #chemicaRNAsynthesis, enabling >200-nt RNAs. Supports sgRNAs and 5′-capped mRNAs with strong translation and precise mods. Site-specific 2′-OMe poly(A) boosts protein expression. 🧬Read more: doi.org/10.1093/nar/...
#NARBreakthrough
🌟 2026 Nucleic Acids Research Database issue 🧬
182 papers, 84 new databases, plus Breakthrough Articles on JoGo (global long‑read haplotypes) and So3D (3D spatial genomics). Browse the issue and Editorial: academic.oup.com/nar/issue/54...
academic.oup.com/nar/article/...
@danielrigden.bsky.social
182 papers, 84 new databases, plus Breakthrough Articles on JoGo (global long‑read haplotypes) and So3D (3D spatial genomics). Browse the issue and Editorial: academic.oup.com/nar/issue/54...
academic.oup.com/nar/article/...
@danielrigden.bsky.social
January 19, 2026 at 9:06 AM
🌟 2026 Nucleic Acids Research Database issue 🧬
182 papers, 84 new databases, plus Breakthrough Articles on JoGo (global long‑read haplotypes) and So3D (3D spatial genomics). Browse the issue and Editorial: academic.oup.com/nar/issue/54...
academic.oup.com/nar/article/...
@danielrigden.bsky.social
182 papers, 84 new databases, plus Breakthrough Articles on JoGo (global long‑read haplotypes) and So3D (3D spatial genomics). Browse the issue and Editorial: academic.oup.com/nar/issue/54...
academic.oup.com/nar/article/...
@danielrigden.bsky.social
⭐NAR Breakthrough! ⭐
🔬 #tRNA modifications fine-tune #translation; in yeast, their loss slows #ribosomes at hard-to-read codon pairs, causing collisions ⚠️, and cells deploy quality control pathways to prevent #proteotoxicstress and ensure survival.
🧬Read more: doi.org/10.1093/nar/...
🔬 #tRNA modifications fine-tune #translation; in yeast, their loss slows #ribosomes at hard-to-read codon pairs, causing collisions ⚠️, and cells deploy quality control pathways to prevent #proteotoxicstress and ensure survival.
🧬Read more: doi.org/10.1093/nar/...
December 23, 2025 at 4:03 PM
⭐NAR Breakthrough! ⭐
🔬 #tRNA modifications fine-tune #translation; in yeast, their loss slows #ribosomes at hard-to-read codon pairs, causing collisions ⚠️, and cells deploy quality control pathways to prevent #proteotoxicstress and ensure survival.
🧬Read more: doi.org/10.1093/nar/...
🔬 #tRNA modifications fine-tune #translation; in yeast, their loss slows #ribosomes at hard-to-read codon pairs, causing collisions ⚠️, and cells deploy quality control pathways to prevent #proteotoxicstress and ensure survival.
🧬Read more: doi.org/10.1093/nar/...
⭐NAR Breakthrough! ⭐
🧬 A synthetic RNA forms a #G-quadruplex without a G-rich sequence, using a complex 3D fold and GTP as a ligand. This suggests G-quadruplexes may be far more widespread in biologically important RNAs. Read more: doi.org/10.1093/nar/...
#NARBreaktrhough #RNA #StructuralBiology
🧬 A synthetic RNA forms a #G-quadruplex without a G-rich sequence, using a complex 3D fold and GTP as a ligand. This suggests G-quadruplexes may be far more widespread in biologically important RNAs. Read more: doi.org/10.1093/nar/...
#NARBreaktrhough #RNA #StructuralBiology
December 22, 2025 at 3:48 PM
⭐NAR Breakthrough! ⭐
🧬 A synthetic RNA forms a #G-quadruplex without a G-rich sequence, using a complex 3D fold and GTP as a ligand. This suggests G-quadruplexes may be far more widespread in biologically important RNAs. Read more: doi.org/10.1093/nar/...
#NARBreaktrhough #RNA #StructuralBiology
🧬 A synthetic RNA forms a #G-quadruplex without a G-rich sequence, using a complex 3D fold and GTP as a ligand. This suggests G-quadruplexes may be far more widespread in biologically important RNAs. Read more: doi.org/10.1093/nar/...
#NARBreaktrhough #RNA #StructuralBiology
🔬 #Trypanosomes process their large rRNA in a highly unusual way-by cutting it into six pieces. A new study from @schneian.bsky.social lab identified two essential proteins, TbLrRP1 and TbLrRP2, that drive this process. Read more: doi.org/10.1093/nar/...
#NARBreakthrough #RibosomeBiogenesis
#NARBreakthrough #RibosomeBiogenesis
December 15, 2025 at 4:25 PM
🔬 #Trypanosomes process their large rRNA in a highly unusual way-by cutting it into six pieces. A new study from @schneian.bsky.social lab identified two essential proteins, TbLrRP1 and TbLrRP2, that drive this process. Read more: doi.org/10.1093/nar/...
#NARBreakthrough #RibosomeBiogenesis
#NARBreakthrough #RibosomeBiogenesis
Congratulations @simrouxvirus.bsky.social
@maureenbug.bsky.social
@titus.idyll.org
@taylorreiter.bsky.social
@ucdavis.bsky.social on this fantastic publication, and thank you for this informative thread!
#NARGenomics #NARGAB #EditorsChoice #GenomeAssembly #Sequencing
@maureenbug.bsky.social
@titus.idyll.org
@taylorreiter.bsky.social
@ucdavis.bsky.social on this fantastic publication, and thank you for this informative thread!
#NARGenomics #NARGAB #EditorsChoice #GenomeAssembly #Sequencing
🧬🦠🚨 Another new paper alert, this time led by @maureenbug.bsky.social ! In collaboration with the Emerson lab and
@titus.idyll.org lab (@taylorreiter.bsky.social), both at UC Davis. Asking the question: what are we missing in short-read metagenome assembly, and why ?
doi.org/10.1093/narg...
@titus.idyll.org lab (@taylorreiter.bsky.social), both at UC Davis. Asking the question: what are we missing in short-read metagenome assembly, and why ?
doi.org/10.1093/narg...
Comparison of short-read and long-read metagenome assemblies in a natural soil community highlights systematic bias in recovery of high-diversity populations
Abstract. Comparisons of long-read and short-read (meta)genome assemblies typically show that short-read sequence assemblies are less error-prone, but stru
doi.org
December 12, 2025 at 6:11 AM
Congratulations @simrouxvirus.bsky.social
@maureenbug.bsky.social
@titus.idyll.org
@taylorreiter.bsky.social
@ucdavis.bsky.social on this fantastic publication, and thank you for this informative thread!
#NARGenomics #NARGAB #EditorsChoice #GenomeAssembly #Sequencing
@maureenbug.bsky.social
@titus.idyll.org
@taylorreiter.bsky.social
@ucdavis.bsky.social on this fantastic publication, and thank you for this informative thread!
#NARGenomics #NARGAB #EditorsChoice #GenomeAssembly #Sequencing
📢 Read this timely review in #NARCancer! 🧬
Gueble and Menon highlight the critical role of #DNAhelicases in linking #DNAdamage recognition with #repair. The review includes a curated table of #clinicaltrials on #helicaseinhibitors.
Read it here: doi.org/10.1093/narc... @yalepress.bsky.social
Gueble and Menon highlight the critical role of #DNAhelicases in linking #DNAdamage recognition with #repair. The review includes a curated table of #clinicaltrials on #helicaseinhibitors.
Read it here: doi.org/10.1093/narc... @yalepress.bsky.social
DNA repair helicases: from mechanistic understanding to therapeutic implications
Abstract. The maintenance of genomic integrity is paramount for normal cell physiology and survival as well as avoidance of carcinogenesis. Cellular DNA is
doi.org
December 10, 2025 at 4:11 PM
📢 Read this timely review in #NARCancer! 🧬
Gueble and Menon highlight the critical role of #DNAhelicases in linking #DNAdamage recognition with #repair. The review includes a curated table of #clinicaltrials on #helicaseinhibitors.
Read it here: doi.org/10.1093/narc... @yalepress.bsky.social
Gueble and Menon highlight the critical role of #DNAhelicases in linking #DNAdamage recognition with #repair. The review includes a curated table of #clinicaltrials on #helicaseinhibitors.
Read it here: doi.org/10.1093/narc... @yalepress.bsky.social
Reposted by Nucleic Acids Research
We're excited to release metaTraits.embl.de! 🦠 Interactively explore 140+ 𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗮𝗹 𝗽𝗵𝗲𝗻𝗼𝘁𝘆𝗽𝗶𝗰 𝘁𝗿𝗮𝗶𝘁𝘀, harmonized & integrated from culture-derived collections 🔬 & genome-based predictions 🧬 for >2M MAGs & genomes.
Publication at NAR: doi.org/10.1093/nar/... @narjournal.bsky.social #microsky 🧵 1/8
Publication at NAR: doi.org/10.1093/nar/... @narjournal.bsky.social #microsky 🧵 1/8
December 2, 2025 at 5:52 PM
We're excited to release metaTraits.embl.de! 🦠 Interactively explore 140+ 𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗮𝗹 𝗽𝗵𝗲𝗻𝗼𝘁𝘆𝗽𝗶𝗰 𝘁𝗿𝗮𝗶𝘁𝘀, harmonized & integrated from culture-derived collections 🔬 & genome-based predictions 🧬 for >2M MAGs & genomes.
Publication at NAR: doi.org/10.1093/nar/... @narjournal.bsky.social #microsky 🧵 1/8
Publication at NAR: doi.org/10.1093/nar/... @narjournal.bsky.social #microsky 🧵 1/8
Reposted by Nucleic Acids Research
From one of the @ebi.embl.org team, published in @narjournal.bsky.social #NARDatabaseIssue | ChEBI: re-engineered for a sustainable future | #Bioinformatics #Database #Chemistry #OpenData #OpenScience #ChemicalEntitiesofBiologicalInterest 🧬 🖥️🧪🔓
⬇️
academic.oup.com/nar/advance-...
⬇️
academic.oup.com/nar/advance-...
ChEBI: re-engineered for a sustainable future
Abstract. Chemical Entities of Biological Interest (ChEBI) is a high-quality, manually curated, and open-access database and ontology of chemical entities
academic.oup.com
November 29, 2025 at 5:38 PM
From one of the @ebi.embl.org team, published in @narjournal.bsky.social #NARDatabaseIssue | ChEBI: re-engineered for a sustainable future | #Bioinformatics #Database #Chemistry #OpenData #OpenScience #ChemicalEntitiesofBiologicalInterest 🧬 🖥️🧪🔓
⬇️
academic.oup.com/nar/advance-...
⬇️
academic.oup.com/nar/advance-...
📢Paper spotlight in NAR Cancer 🧬
A new study in #NARCancer introduces #THRESHOLD, a novel framework that measures gene expression “saturation” 📊—how consistently genes are expressed across cancer patients!
Read the full article here: doi.org/10.1093/narc...
#Transcriptomics #PrecisionOncology
A new study in #NARCancer introduces #THRESHOLD, a novel framework that measures gene expression “saturation” 📊—how consistently genes are expressed across cancer patients!
Read the full article here: doi.org/10.1093/narc...
#Transcriptomics #PrecisionOncology
THRESHOLD: a comprehensive transcriptomic analysis tool for evaluating gene saturation and impact in disease progression
Abstract. Gene expression studies are fundamental in molecular biology, offering insights into development, disease progression, and therapeutic targets. T
doi.org
December 9, 2025 at 7:59 PM
📢Paper spotlight in NAR Cancer 🧬
A new study in #NARCancer introduces #THRESHOLD, a novel framework that measures gene expression “saturation” 📊—how consistently genes are expressed across cancer patients!
Read the full article here: doi.org/10.1093/narc...
#Transcriptomics #PrecisionOncology
A new study in #NARCancer introduces #THRESHOLD, a novel framework that measures gene expression “saturation” 📊—how consistently genes are expressed across cancer patients!
Read the full article here: doi.org/10.1093/narc...
#Transcriptomics #PrecisionOncology
Reposted by Nucleic Acids Research
🚨 Out in NAR @narjournal.bsky.social!
Introducing HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences.
📄 Paper: doi.org/10.1093/nar/...
💻 DB: bcglab.cibio.unitn.it/hapscoredb
#Bioinformatics #Genomics #ProteinLanguageModels #CompBio
Introducing HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences.
📄 Paper: doi.org/10.1093/nar/...
💻 DB: bcglab.cibio.unitn.it/hapscoredb
#Bioinformatics #Genomics #ProteinLanguageModels #CompBio
HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences
Abstract. Deciphering the functional effects of genetic variants, especially those inherited together on the same haplotype, remains a major challenge in h
doi.org
November 25, 2025 at 9:25 AM
🚨 Out in NAR @narjournal.bsky.social!
Introducing HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences.
📄 Paper: doi.org/10.1093/nar/...
💻 DB: bcglab.cibio.unitn.it/hapscoredb
#Bioinformatics #Genomics #ProteinLanguageModels #CompBio
Introducing HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences.
📄 Paper: doi.org/10.1093/nar/...
💻 DB: bcglab.cibio.unitn.it/hapscoredb
#Bioinformatics #Genomics #ProteinLanguageModels #CompBio
⭐ NAR Breakthrough! ⭐
🦠 New study shows phage X1 hijacks Yersinia's enterocolitica flagellum to inject its DNA directly into the cytosol. Yersinia, though, strikes back!
🦠 A fascinating look at the #dualrole of #flagella in #viralentry and #bacterialimmunity.
🧬 Read more: doi.org/10.1093/nar/...
🦠 New study shows phage X1 hijacks Yersinia's enterocolitica flagellum to inject its DNA directly into the cytosol. Yersinia, though, strikes back!
🦠 A fascinating look at the #dualrole of #flagella in #viralentry and #bacterialimmunity.
🧬 Read more: doi.org/10.1093/nar/...
November 25, 2025 at 5:10 PM
⭐ NAR Breakthrough! ⭐
🦠 New study shows phage X1 hijacks Yersinia's enterocolitica flagellum to inject its DNA directly into the cytosol. Yersinia, though, strikes back!
🦠 A fascinating look at the #dualrole of #flagella in #viralentry and #bacterialimmunity.
🧬 Read more: doi.org/10.1093/nar/...
🦠 New study shows phage X1 hijacks Yersinia's enterocolitica flagellum to inject its DNA directly into the cytosol. Yersinia, though, strikes back!
🦠 A fascinating look at the #dualrole of #flagella in #viralentry and #bacterialimmunity.
🧬 Read more: doi.org/10.1093/nar/...
⭐ NAR Breakthrough! ⭐
🔬 New study reveals how the Retron-Eco7 system helps bacteria sense and fight phage attacks, identifying a clever immune-sensing mechanism in the bacteria–phage arms race.
🧬 Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Microbiology #PhageBiology #BacterialDefense
🔬 New study reveals how the Retron-Eco7 system helps bacteria sense and fight phage attacks, identifying a clever immune-sensing mechanism in the bacteria–phage arms race.
🧬 Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Microbiology #PhageBiology #BacterialDefense
November 24, 2025 at 6:16 PM
⭐ NAR Breakthrough! ⭐
🔬 New study reveals how the Retron-Eco7 system helps bacteria sense and fight phage attacks, identifying a clever immune-sensing mechanism in the bacteria–phage arms race.
🧬 Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Microbiology #PhageBiology #BacterialDefense
🔬 New study reveals how the Retron-Eco7 system helps bacteria sense and fight phage attacks, identifying a clever immune-sensing mechanism in the bacteria–phage arms race.
🧬 Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Microbiology #PhageBiology #BacterialDefense
⭐ NAR Breakthrough! ⭐
🔬 New study by Betancurt et al. uses #PacBio single-molecule sequencing to build a long-read fidelity assay that reveals how different #DNApolymerase families make distinct errors.
🧬 Read more: doi.org/10.1093/nar/...
@nebiolabs.bsky.social @pasteur.fr
#NARBreakthrough
🔬 New study by Betancurt et al. uses #PacBio single-molecule sequencing to build a long-read fidelity assay that reveals how different #DNApolymerase families make distinct errors.
🧬 Read more: doi.org/10.1093/nar/...
@nebiolabs.bsky.social @pasteur.fr
#NARBreakthrough
November 21, 2025 at 6:18 PM
⭐ NAR Breakthrough! ⭐
🔬 New study by Betancurt et al. uses #PacBio single-molecule sequencing to build a long-read fidelity assay that reveals how different #DNApolymerase families make distinct errors.
🧬 Read more: doi.org/10.1093/nar/...
@nebiolabs.bsky.social @pasteur.fr
#NARBreakthrough
🔬 New study by Betancurt et al. uses #PacBio single-molecule sequencing to build a long-read fidelity assay that reveals how different #DNApolymerase families make distinct errors.
🧬 Read more: doi.org/10.1093/nar/...
@nebiolabs.bsky.social @pasteur.fr
#NARBreakthrough
⭐ NAR Breakthrough! ⭐
A community-driven collection uniting 52 phages, 74 Klebsiella isolates, and extensive genomic + phenotypic data — all freely available at klebphacol.org.
🧬 Learn more: doi.org/10.1093/nar/...
@fnobrega.bsky.social @danielarothschild.bsky.social #antimicrobialresistance
A community-driven collection uniting 52 phages, 74 Klebsiella isolates, and extensive genomic + phenotypic data — all freely available at klebphacol.org.
🧬 Learn more: doi.org/10.1093/nar/...
@fnobrega.bsky.social @danielarothschild.bsky.social #antimicrobialresistance
November 20, 2025 at 6:01 PM
⭐ NAR Breakthrough! ⭐
A community-driven collection uniting 52 phages, 74 Klebsiella isolates, and extensive genomic + phenotypic data — all freely available at klebphacol.org.
🧬 Learn more: doi.org/10.1093/nar/...
@fnobrega.bsky.social @danielarothschild.bsky.social #antimicrobialresistance
A community-driven collection uniting 52 phages, 74 Klebsiella isolates, and extensive genomic + phenotypic data — all freely available at klebphacol.org.
🧬 Learn more: doi.org/10.1093/nar/...
@fnobrega.bsky.social @danielarothschild.bsky.social #antimicrobialresistance
📣 Authors wanted! Submit to NARMME's Special Collection on Repeat Expansion Diseases by Jan 2026🧬
🔍Find out more: academic.oup.com/narmolmed/pa...
👉Submit: mc.manuscriptcentral.com/narmme
#CallForPapers #Genomics #RareDiseases #NARMME
🔍Find out more: academic.oup.com/narmolmed/pa...
👉Submit: mc.manuscriptcentral.com/narmme
#CallForPapers #Genomics #RareDiseases #NARMME
October 30, 2025 at 10:28 AM
📣 Authors wanted! Submit to NARMME's Special Collection on Repeat Expansion Diseases by Jan 2026🧬
🔍Find out more: academic.oup.com/narmolmed/pa...
👉Submit: mc.manuscriptcentral.com/narmme
#CallForPapers #Genomics #RareDiseases #NARMME
🔍Find out more: academic.oup.com/narmolmed/pa...
👉Submit: mc.manuscriptcentral.com/narmme
#CallForPapers #Genomics #RareDiseases #NARMME
🧬 New in NARGAB: A fast, scalable CHT method identifies genomic regions with shared effects across traits. Applied to psychiatric pleiotropy and cucumber virus resistance.
Read: doi.org/10.1093/narg...
#CHT #MultiTraitAnalysis #PsychiatricGenetics #PlantGenomics
Read: doi.org/10.1093/narg...
#CHT #MultiTraitAnalysis #PsychiatricGenetics #PlantGenomics
October 16, 2025 at 3:45 PM
🧬 New in NARGAB: A fast, scalable CHT method identifies genomic regions with shared effects across traits. Applied to psychiatric pleiotropy and cucumber virus resistance.
Read: doi.org/10.1093/narg...
#CHT #MultiTraitAnalysis #PsychiatricGenetics #PlantGenomics
Read: doi.org/10.1093/narg...
#CHT #MultiTraitAnalysis #PsychiatricGenetics #PlantGenomics
🧬 New in NARMME: RNA splicing tweaks rescue tau toxicity in C. elegans. Modifying tri-snRNP proteins rescues tau-induced deficits in transgenic C. elegans, restoring behaviour, neurodegeneration and extending lifespan.
Read: doi.org/10.1093/narm...
#Alzheimers #RNAsplicing #Neurodegeneration
Read: doi.org/10.1093/narm...
#Alzheimers #RNAsplicing #Neurodegeneration
October 16, 2025 at 3:41 PM
🧬 New in NARMME: RNA splicing tweaks rescue tau toxicity in C. elegans. Modifying tri-snRNP proteins rescues tau-induced deficits in transgenic C. elegans, restoring behaviour, neurodegeneration and extending lifespan.
Read: doi.org/10.1093/narm...
#Alzheimers #RNAsplicing #Neurodegeneration
Read: doi.org/10.1093/narm...
#Alzheimers #RNAsplicing #Neurodegeneration
⭐ NAR Breakthrough! ⭐
🔬 How do #kinetochores rebuild each #cellcycle?
A new study reveals the order of assembly, hidden interdependencies, and a new regulatory mechanism.
🧬 Read more: academic.oup.com/nar/article/... @suebiggins.bsky.social @fredhutch.org
#NARbreakthrough #ChromosomeSegregation
🔬 How do #kinetochores rebuild each #cellcycle?
A new study reveals the order of assembly, hidden interdependencies, and a new regulatory mechanism.
🧬 Read more: academic.oup.com/nar/article/... @suebiggins.bsky.social @fredhutch.org
#NARbreakthrough #ChromosomeSegregation
October 15, 2025 at 1:49 PM
⭐ NAR Breakthrough! ⭐
🔬 How do #kinetochores rebuild each #cellcycle?
A new study reveals the order of assembly, hidden interdependencies, and a new regulatory mechanism.
🧬 Read more: academic.oup.com/nar/article/... @suebiggins.bsky.social @fredhutch.org
#NARbreakthrough #ChromosomeSegregation
🔬 How do #kinetochores rebuild each #cellcycle?
A new study reveals the order of assembly, hidden interdependencies, and a new regulatory mechanism.
🧬 Read more: academic.oup.com/nar/article/... @suebiggins.bsky.social @fredhutch.org
#NARbreakthrough #ChromosomeSegregation
Five years ago, Dr. Doudna @jenniferdoudna.bsky.social and Dr. Charpentier won the #NobelPrize for #CRISPR/Cas9, revolutionizing gene editing and science as we know it. 🎉🎉Celebrate this milestone with our #specialcollections academic.oup.com/nar/pages/cr... and academic.oup.com/nar/pages/cr...
October 7, 2025 at 5:48 AM
Five years ago, Dr. Doudna @jenniferdoudna.bsky.social and Dr. Charpentier won the #NobelPrize for #CRISPR/Cas9, revolutionizing gene editing and science as we know it. 🎉🎉Celebrate this milestone with our #specialcollections academic.oup.com/nar/pages/cr... and academic.oup.com/nar/pages/cr...
⭐ NAR Breakthrough! ⭐
New research highlights CHD1L in the chromosome 1q21.1 region—linked to #autism, head size & growth.
🧠 It controls #DNApackaging & genes for #braindevelopment, #cellfate & #connectivity.
Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Neuroscience @igbmc.bsky.social
New research highlights CHD1L in the chromosome 1q21.1 region—linked to #autism, head size & growth.
🧠 It controls #DNApackaging & genes for #braindevelopment, #cellfate & #connectivity.
Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Neuroscience @igbmc.bsky.social
Disrupted transcriptional networks regulated by CHD1L during neurodevelopment underlie the mirrored neuroanatomical and growth phenotypes of the 1q21.1 copy number variant
Abstract. Distal 1q21.1 deletions and duplications are associated with variable phenotypes including autism, head circumference and height defects. To eluc
doi.org
September 24, 2025 at 5:34 PM
⭐ NAR Breakthrough! ⭐
New research highlights CHD1L in the chromosome 1q21.1 region—linked to #autism, head size & growth.
🧠 It controls #DNApackaging & genes for #braindevelopment, #cellfate & #connectivity.
Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Neuroscience @igbmc.bsky.social
New research highlights CHD1L in the chromosome 1q21.1 region—linked to #autism, head size & growth.
🧠 It controls #DNApackaging & genes for #braindevelopment, #cellfate & #connectivity.
Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Neuroscience @igbmc.bsky.social
🧬 New in NARGAB: authors compared human exome sequencing kits, showing how design differences impact capture efficiency and downstream analysis. Useful insights for choosing the right kit!
📖 Read: doi.org/10.1093/narg...
#ExomeSequencing #Genomics #Bioinformatics #NARGAB
📖 Read: doi.org/10.1093/narg...
#ExomeSequencing #Genomics #Bioinformatics #NARGAB
September 22, 2025 at 2:19 PM
🧬 New in NARGAB: authors compared human exome sequencing kits, showing how design differences impact capture efficiency and downstream analysis. Useful insights for choosing the right kit!
📖 Read: doi.org/10.1093/narg...
#ExomeSequencing #Genomics #Bioinformatics #NARGAB
📖 Read: doi.org/10.1093/narg...
#ExomeSequencing #Genomics #Bioinformatics #NARGAB
🧬New in NARGAB: a composite hypothesis testing (CHT) method to find genetic regions affecting multiple traits is described which is efficient, scalable and applied to psychiatric disorders and viral resistance in cucumber.
Read here: doi.org/10.1093/narg...
#Genomics #CHT #Bioinformatics #NARGAB
Read here: doi.org/10.1093/narg...
#Genomics #CHT #Bioinformatics #NARGAB
September 22, 2025 at 2:16 PM
🧬New in NARGAB: a composite hypothesis testing (CHT) method to find genetic regions affecting multiple traits is described which is efficient, scalable and applied to psychiatric disorders and viral resistance in cucumber.
Read here: doi.org/10.1093/narg...
#Genomics #CHT #Bioinformatics #NARGAB
Read here: doi.org/10.1093/narg...
#Genomics #CHT #Bioinformatics #NARGAB
🤰 New research in NARMME reveals that uterine glands, not just eggs, are sensitive to maternal aging. 🧬 FOXC1 marks early dysfunction, reshaping how we understand fertility decline.
📖 Read more: lnkd.in/eahrVbMt
#FertilityResearch #FOXC1 #ReproductiveScience #NARMME #OpenAccessPublication
📖 Read more: lnkd.in/eahrVbMt
#FertilityResearch #FOXC1 #ReproductiveScience #NARMME #OpenAccessPublication
September 19, 2025 at 5:04 PM
🤰 New research in NARMME reveals that uterine glands, not just eggs, are sensitive to maternal aging. 🧬 FOXC1 marks early dysfunction, reshaping how we understand fertility decline.
📖 Read more: lnkd.in/eahrVbMt
#FertilityResearch #FOXC1 #ReproductiveScience #NARMME #OpenAccessPublication
📖 Read more: lnkd.in/eahrVbMt
#FertilityResearch #FOXC1 #ReproductiveScience #NARMME #OpenAccessPublication
💡 New in NARMME: TRL1 enzyme from Candida glabrata changes shape to control RNA repair, vital for fungal survival. Its absence in humans makes it a promising antifungal drug target.
📖 Read more: doi.org/10.1093/narm...
#TRL1 #RNARepair #AntifungalResearch #DrugDiscovery #NARMME #OpenAccess
📖 Read more: doi.org/10.1093/narm...
#TRL1 #RNARepair #AntifungalResearch #DrugDiscovery #NARMME #OpenAccess
September 18, 2025 at 4:56 PM
💡 New in NARMME: TRL1 enzyme from Candida glabrata changes shape to control RNA repair, vital for fungal survival. Its absence in humans makes it a promising antifungal drug target.
📖 Read more: doi.org/10.1093/narm...
#TRL1 #RNARepair #AntifungalResearch #DrugDiscovery #NARMME #OpenAccess
📖 Read more: doi.org/10.1093/narm...
#TRL1 #RNARepair #AntifungalResearch #DrugDiscovery #NARMME #OpenAccess