Macrophysiological System
@invitroveritas.bsky.social
I'm like the full-sized version of an organ-on-a-chip. Brain organoids, veganism, feminism, pragmatic progressivism, sometimes grad school & parenting. Critics rave: "The least annoying bad takes I've seen all week"
But organoid circuits don't map one-to-one onto brain circuits, & we can't know if the effects of ASD-linked perturbations are the same as in brains.
Messaging & grants should reflect this, to ensure this basic neurodev research doesn't take funding meant for the growing needs of the ASD community
Messaging & grants should reflect this, to ensure this basic neurodev research doesn't take funding meant for the growing needs of the ASD community
December 13, 2024 at 5:59 PM
But organoid circuits don't map one-to-one onto brain circuits, & we can't know if the effects of ASD-linked perturbations are the same as in brains.
Messaging & grants should reflect this, to ensure this basic neurodev research doesn't take funding meant for the growing needs of the ASD community
Messaging & grants should reflect this, to ensure this basic neurodev research doesn't take funding meant for the growing needs of the ASD community
Do different neuron types have to appear at specific times relative to each other, or can they wait for their circuit partners if need be? Does spliceosome regulation have a big role during neurogenesis?
If these processes are affected in brain models with ASD-like perturbations, it's a good clue!
If these processes are affected in brain models with ASD-like perturbations, it's a good clue!
December 13, 2024 at 5:59 PM
Do different neuron types have to appear at specific times relative to each other, or can they wait for their circuit partners if need be? Does spliceosome regulation have a big role during neurogenesis?
If these processes are affected in brain models with ASD-like perturbations, it's a good clue!
If these processes are affected in brain models with ASD-like perturbations, it's a good clue!
thank you!!
December 9, 2024 at 2:10 AM
thank you!!
Super cool, I might try that recipe! But I also think there's a huge unexplored space of fermented coagulated plant milks, beyond trying to replicate existing dairy cheeses
December 8, 2024 at 3:50 AM
Super cool, I might try that recipe! But I also think there's a huge unexplored space of fermented coagulated plant milks, beyond trying to replicate existing dairy cheeses
I like the Daiya-style emulsified stuff, but real cheesemaking w plant milks is a big opportunity.
Imagine being sent to the Neolithic to reinvent cheesemaking, knowing all the modern techniques—inoculation, brining, climate-controlled caves. That's where we are for cashew, macadamia, & pea milk!
December 8, 2024 at 2:51 AM
I like the Daiya-style emulsified stuff, but real cheesemaking w plant milks is a big opportunity.
Imagine being sent to the Neolithic to reinvent cheesemaking, knowing all the modern techniques—inoculation, brining, climate-controlled caves. That's where we are for cashew, macadamia, & pea milk!
The rest of us are missing out on tofu fermentation foodways that rival any dairy cheesemaking tradition: smelly tofu, pickled tofu, creamy tofu, squeaky tofu, mushy tofu!
(The good folks at the Soyinfo center have all the details:
soyinfocenter.com/pdf/149/ToFe...) 2/3
(The good folks at the Soyinfo center have all the details:
soyinfocenter.com/pdf/149/ToFe...) 2/3
December 8, 2024 at 2:51 AM
The rest of us are missing out on tofu fermentation foodways that rival any dairy cheesemaking tradition: smelly tofu, pickled tofu, creamy tofu, squeaky tofu, mushy tofu!
(The good folks at the Soyinfo center have all the details:
soyinfocenter.com/pdf/149/ToFe...) 2/3
(The good folks at the Soyinfo center have all the details:
soyinfocenter.com/pdf/149/ToFe...) 2/3
Thanks! It's 16"x20", I might have gone a little smaller but the bark is delicate when cut too thin and I was using a dull blade when I started. A fresh xacto blade definitely helps with finer details
December 7, 2024 at 1:39 PM
Thanks! It's 16"x20", I might have gone a little smaller but the bark is delicate when cut too thin and I was using a dull blade when I started. A fresh xacto blade definitely helps with finer details
@neurowoodworks.bsky.social, what do you think?
December 7, 2024 at 4:17 AM
@neurowoodworks.bsky.social, what do you think?
just remember, it could be worse: bsky.app/profile/invi...
November 18, 2024 at 1:58 PM
just remember, it could be worse: bsky.app/profile/invi...
I'd love to join! PhD candidate working with neural organoids
November 16, 2024 at 3:44 PM
I'd love to join! PhD candidate working with neural organoids
oof—five full workweeks to analyze a single embryo like this. Never going to complain about debugging an ImageJ macro again
November 15, 2024 at 6:38 PM
oof—five full workweeks to analyze a single embryo like this. Never going to complain about debugging an ImageJ macro again
In general, we need to get past a pure deficit model of #scicomm.
Some distrust is due to lack of understanding. But if we feel the need to scrupulously hide what we're doing from the public that funds it, our professional values may have diverged from theirs enough to need a course correction
Some distrust is due to lack of understanding. But if we feel the need to scrupulously hide what we're doing from the public that funds it, our professional values may have diverged from theirs enough to need a course correction
November 15, 2024 at 3:21 PM
In general, we need to get past a pure deficit model of #scicomm.
Some distrust is due to lack of understanding. But if we feel the need to scrupulously hide what we're doing from the public that funds it, our professional values may have diverged from theirs enough to need a course correction
Some distrust is due to lack of understanding. But if we feel the need to scrupulously hide what we're doing from the public that funds it, our professional values may have diverged from theirs enough to need a course correction
I'd love to be added too!
November 14, 2024 at 8:29 PM
I'd love to be added too!