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Reposted by Institute for Protein Innovation

Addgene @addgene.bsky.social · 14h

Chonnettia Jones, Addgene’s President & Executive Director, is one of Endpoints News’ 2025 Top Women in Biopharma R&D! She is driving Addgene’s growth to enable more discovery and innovation, powered by the sharing of scientific resources.
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endpoints.news

Meet 20 women reshaping biopharma, from early discovery to patient advocacy

twp.ai

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Institute for Protein Innovation @ipiproteins.bsky.social · 2d

For Chang Yang, science is personal. The early loss of her grandmother to cancer inspired a career in #biotechnology — and, at IPI, she found the tools and mentorship to grow as a scientist.

Read more: buff.ly/Eif7FQB

Chang Yang grows with IPI — and goes beyond

When Chang Yang joined the Institute for Protein Innovation (IPI) in 2021, she was just beginning her career — and IPI was a small nonprofit lab still

buff.ly

Institute for Protein Innovation @ipiproteins.bsky.social · 6d

“What drives my research is my passion for immunology,” says IPI #researchassociate Fabbiha Hossain.

Here at IPI, we play a role , but our #proteinreagents go on to impact #biologicaldiscovery in a multitude of ways, including in the field of #immunology.

Learn more about IPI: buff.ly/HHMWKf5

Institute for Protein Innovation @ipiproteins.bsky.social · 8d

Using a synthetic yeast display nanobody library, IPI cofounder Andrew Kruse & @harvardmed.bsky.social colleagues found #nanobodies that modulate AT1R function, distinct from small molecules.

A promising step for nanobody drugs & compelling use of #yeastdisplay ➡️ academic.oup.com/mam/article/...

Structural Insights into Antibody-based Inhibition of the Angiotensin Receptor

The angiotensin II type I receptor (AT1R), a G protein-coupled receptor (GPCR) that regulates cardiac and renal function, is one of the most successful pha

academic.oup.com

Institute for Protein Innovation @ipiproteins.bsky.social · 12d

Or earn more about our platform! 🔬 buff.ly/EAHs2vg

Platform

IPI's Antibody Platform, constructed around sophisticated yeast display technology, generates synthetic, recombinant antibodies.

buff.ly

Institute for Protein Innovation @ipiproteins.bsky.social · 12d

Explore our antibody catalog for proteins related to neuroscience targets and more 🇾 buff.ly/T2PylyV

Protein tools

IPI is proud to provide high-quality, well-validated recombinant antibodies and other protein tools to the biological research community. We prioritize difficul

proteininnovation.org

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Institute for Protein Innovation @ipiproteins.bsky.social · 12d

If you missed us, read up on axon guidance and the main protein families involved in our canonical families of proteins involved in axonal pathfinding 🧠 buff.ly/DzejVfg

Axon Guidance: Explained

In the late 19th century, neuroscientist Santiago Ramón y Cajal peered through a microscope at the spinal cords of three-day-old chick embryos and drew

proteininnovation.org

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Institute for Protein Innovation @ipiproteins.bsky.social · 12d

It’s conference season! We're just back from AXON2025 & Discovery on Target where we: shared progress on antibodies to 50+ neuronal targets, discussed strategies for #membraneprotein and #GPCR discovery & met determined researchers in #braindevelopment #synapticplasticity #antibodydiscovery & more.

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Institute for Protein Innovation @ipiproteins.bsky.social · 13d

This fall, Chang Yang begins a new chapter: a Ph.D. program in biochemistry @uwmadison.bsky.social, leaving behind a legacy of collaboration, innovation and growth at IPI.

Read her story: buff.ly/y5mxi3X

Reposted by Institute for Protein Innovation

bioRxiv Developmental Biology @biorxiv-devbio.bsky.social · 22d

Patterned integrin-laminin adhesion coordinates epithelial collective cell migration https://www.biorxiv.org/content/10.1101/2025.09.12.675859v1

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Institute for Protein Innovation @ipiproteins.bsky.social · 14d

Research at IPI directly impacts discovery — and this is a big part of what motivates IPI scientist Rebecca Hershman in the lab.

#proteinscience #proteomics #antibodydiscovery #proteininnovation 💪⚖️

buff.ly/HLvHdPR

Institute for Protein Innovation @ipiproteins.bsky.social · 15d

Frequent user of epitope tags? Try ours!

IPI epitope tag antibodies & plasmids are now available through our partner @addgene.bsky.social!

buff.ly/YEuZDIp

Epitope tag antibody collection

Epitope tags are short amino acid sequences fused to a protein’s N- or C-terminus. When paired with an antibody that specifically recognizes this sequence, epit

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Institute for Protein Innovation @ipiproteins.bsky.social · 20d

What drives science forward? People like Senior Automation Engineer Eloy Salinas, who is always on the lookout for ways to innovate in the lab.

Learn more about the IPI platform: buff.ly/91pXA1d

#proteinscience #proteome #labautomation #proteininnovation

Institute for Protein Innovation @ipiproteins.bsky.social · 21d

Come find us to learn more about IPI!
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Institute for Protein Innovation @ipiproteins.bsky.social · 21d

Lots of excitement at the Discovery on Target conference next week!
🎯André Teixeira will share IPI's high-throughput discovery platform and lead a discussion on GPCR #abdiscovery (Sept. 23)
🎯IPI co-founder Tim Springer will give a keynote on #integrins and their role in organoid formation (Sept. 24)

Antibodies Against Membrane Protein Targets | Discovery on Target | Sept 22 - 25, 2025

Antibodies Against Membrane Protein Targets provides a forum in which discovery biologists and protein engineers can come together to discuss biologic drugs for the GPCR and more!

www.discoveryontarget.com

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Institute for Protein Innovation @ipiproteins.bsky.social · 22d

Big week at the International Antibody Validation Meeting!

Deb Moshinsky shared our #abvalidation system, already powering our #GPCs & #NLGN antibodies, and Travis Riedel noted the need for validated GPC #monoclonals.

Even better — we connected with scientists pushing antibody validation forward!

Institute for Protein Innovation @ipiproteins.bsky.social · 27d

Prabakaran Ponraj is now boosting bioinformatic analysis at IPI — and he’s coauthor on a recent NaturalAntibody paper that mapped #antibody chain preferences & structural interactions to guide better therapeutics.

Read more! www.nature.com/articles/s42...

Conserved heavy/light contacts and germline preferences revealed by a large-scale analysis of natively paired human antibody sequences and structural data

Data mining of large paired heavy-light antibody sequences reveals preferences in germline usage and conserved inter chain contact residues.

www.nature.com

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Institute for Protein Innovation @ipiproteins.bsky.social · 28d

Head to our website for more on IPI: proteininnovation.org/history/?utm...

Our History

IPI's history begins with scientist and entrepreneur Timothy Springer, a professor at Harvard University and Boston Children’s Hospital.

proteininnovation.org

Institute for Protein Innovation @ipiproteins.bsky.social · 28d

What drives Aditi Kachare’s #antibodycharacterization work at IPI? The chance to push science and research forward, a step at a time.

We’re spotlighting the people behind the scenes at IPI this fall. Follow along to see what else drives our science!

#whatdrivesmyscience #proteinscience #bioscience

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Institute for Protein Innovation @ipiproteins.bsky.social · Sep 9

Thanks @addgene.bsky.social, @dshb-antibodies.bsky.social & #NeuroMab for the shoutout in New Biotechnology!

Inspired by #opensourcesoftware, they’re calling for more opensource #antibodies to make science reliable, affordable and shareable.

Read more: www.sciencedirect.com/science/arti...

Open-source antibodies as a path to enhanced research reproducibility and transparency

Antibodies are important tools with diverse uses in biomedical research. However, open access to reliable sources of well-characterized antibodies with unambiguous molecular identities remains an…

pmc.ncbi.nlm.nih.gov

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Institute for Protein Innovation @ipiproteins.bsky.social · Sep 4

At IPI, we’re building #antibodies to explore neurodegenerative targets, including #Ephrin & #Semaphorin. That’s why we’re excited by a landmark data set from @neuroproteome.bsky.social revealing #proteomic signatures in Alzheimer’s, Parkinson’s & more.

Take a look! www.nature.com/articles/s41...

The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging - Nature Medicine

The largest harmonized proteomic dataset of plasma, serum and cerebrospinal fluid samples across major neurodegenerative diseases reveals both disease-specific and transdiagnostic proteomic…

www.nature.com

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Institute for Protein Innovation @ipiproteins.bsky.social · Sep 3

Learn more about IPI: shorturl.at/QXZKv

Homepage

Discover innovative protein science solutions designed to drive biomedical research and improve human health. Explore our antibodies, learning opportunities and research today.

proteininnovation.org

Institute for Protein Innovation @ipiproteins.bsky.social · Sep 3

What drives protein science at IPI? We asked our team — and the answers totally wowed us!

We’re featuring their responses this fall, starting with IPI research associate Robert May. Come along with us on the ride!

#whatdrivesmyscience #proteinscience #bioscience #antibodydiscovery #research

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Institute for Protein Innovation @ipiproteins.bsky.social · Sep 2

Find our antibody characteriazation and validation director Deb Moshinsky in England next week 🇬🇧 Registration is still open for the 5th International Antibody Validation Meeting @uniofbath.bsky.social — join us! #abval25
www.antibodyvalidation.co.uk

5th International Antibody Validation Meeting

www.antibodyvalidation.co.uk

Institute for Protein Innovation @ipiproteins.bsky.social · Aug 29

Thanks for spending the summer with us!

We’re saying a bittersweet goodbye to our wonderful interns, after months of hard work in the lab. Good luck this fall—we look forward to seeing where your paths lead!