jacobsenucla.bsky.social
Steve Jacobsen
@jacobsenucla.bsky.social
340 followers 300 following 1 posts
UCLA Professor and HHMI Investigator interested in plant epigenetics and plant genome editing.
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jacobsenucla.bsky.social
Steve Jacobsen @jacobsenucla.bsky.social · May 1
Our paper is just out www.nature.com/articles/s41... from the Jacobsen, Doudna, and Banfield labs on viral delivery of a tiny CRISPR system for transgene free germline editing in plants, tinyurl.com/3k223r3x. Looking for postdocs to join the team for the next phase of this work!
Viral delivery of an RNA-guided genome editor for transgene-free germline editing in Arabidopsis - Nature Plants
Weiss et al. engineered the tobacco rattle virus to express the RNA-guided TnpB enzyme ISYmu1 and guide RNA for transgene-free germline editing in Arabidopsis thaliana.
www.nature.com
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Reposted by Steve Jacobsen
innovativegenomics.bsky.social
Innovative Genomics Institute @innovativegenomics.bsky.social · Apr 24
In a new paper, IGI's Jennifer Doudna @doudna-lab.bsky.social and Jill Banfield @banfieldlab.bsky.social collaborate with UCLA's @jacobsenucla.bsky.social to create a new, tiny #CRISPR tool for quicker, easier plant genome editing! Read more: ow.ly/6Szs50VGElf
A photo of a mix of green and white Arabidopsis thaliana seedlings. They turn white when a particular gene is knocked out. Here, a tiny CRISPR system was used to modify the mother plant’s DNA, which the white seedlings inherited.
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Reposted by Steve Jacobsen
plantepigenetics.ch
Etienne Bucher 🌾🧬🇪🇺 @plantepigenetics.ch · Mar 14
Hi plant epigenetics fans!
I have updated the Plant Epigenetics Starter Pack to include additional researchers in the field:
@jacobsenucla.bsky.social @pecinka-grp.bsky.social @manavellalab.bsky.social
Please let me know if you wish to be added to the Starter Pack!
go.bsky.app/HyTwdc2
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Reposted by Steve Jacobsen
c-jake-harris.bsky.social
Jake Harris @c-jake-harris.bsky.social · Feb 24
Back-to-back manuscripts from the Jacobsen and Law labs revealing TFs that direct RdDM! Genetics controlling epigenetics. Reminiscent of KRAB ZFs... shorturl.at/TE4PH shorturl.at/QEHDU
Transcription factors instruct DNA methylation patterns in plant reproductive tissues
DNA methylation is maintained by forming self-reinforcing connections with other repressive chromatin modifications, resulting in stably silenced genes and transposons. However, these mechanisms fail ...
shorturl.at
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