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Jeremy Elman @jaelman.bsky.social · 12d

Check out our data! Please reach out if you're interested, we're happy to provide more info and we may have useful datasets (e.g., with extra cleaning or composite variables) to address specific questions. Raw and derived MRI data also available upon request for ~1/2 the cohort.

VETSA @vetsa.bsky.social · 12d

🚨NEW DATA RELEASE🚨

Data from VETSA waves 1-3 is now available for public download from NACDA! This includes cognitive, health, psychosocial and demographic info from our nationwide twin cohort. Future releases will include wave 4 data and derived MRI variables.
www.icpsr.umich.edu/web/ICPSR/st...

Vietnam Era Twin Study of Aging (VETSA), United States, 2002-2019

www.icpsr.umich.edu

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Jeremy Elman @jaelman.bsky.social · 21d

I need a little bit less praise from Claude and a little more self-flagellation

two men are sitting next to each other and one of them says i 'm such an idiot !

ALT: two men are sitting next to each other and one of them says i 'm such an idiot !

media.tenor.com

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Reposted by Jeremy Elman

Matthew Panizzon @matthewpanizzon.bsky.social · Aug 8

New paper out from the lab, demonstrating a robust non-linear relationship between age at menopause and dementia risk. Fantastic work by post-doc Dr. Ursula Saelzler. alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Age of menopause and dementia risk in 10,832 women from the Swedish Twin Registry

INTRODUCTION An earlier age of menopause (AOM) is hypothesized to increase vulnerability to the neuropathological processes of dementia, which begin in midlife. METHODS We tested this hypothesis i.....

alz-journals.onlinelibrary.wiley.com

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Jeremy Elman @jaelman.bsky.social · Aug 1

If belief is trust in the absence of evidence, you could argue no team believes in their catchers more than the Padres

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Reposted by Jeremy Elman

Tyler Bell, PhD. @tylerbellphd.bsky.social · Jul 22

Excited to share my new study with the
VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social published in #JINS showing that moderate-to-severe chronic pain and opioid use are independently related to risk of mild cognitive impairment. tinyurl.com/y88k5z4j

This figure shows a higher rate of mild cognitive impairment among people with moderate to severe chronic pain versus mild or no chronic pain.

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Reposted by Jeremy Elman

Tyler Bell, PhD. @tylerbellphd.bsky.social · Jul 22

Excited to share my new K01 work to understand chronic pain as an AD risk factor - a collaboration of the VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social and Rush Medical University using the ROSMAP data. academic.oup.com/braincomms/a...

Multisite chronic pain: association with cognitive decline and post-mortem Alzheimer’s biomarkers

Bell et al. report that multisite chronic pain in older adults is linked to faster cognitive decline and increased Alzheimer’s disease pathology, particula

academic.oup.com

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Reposted by Jeremy Elman

VETSA @vetsa.bsky.social · Jul 22

Study from Nathan Gillespie testing causal associations of plasma amyloid on total tau using #VETSA twin data.
www.sciencedirect.com/science/arti...

Testing the causal impact of plasma amyloid on total Tau using a genetically informative sample of adult male twins

The amyloid cascade hypothesis predicts that amyloid-beta (Aβ) aggregation drives tau tangle accumulation. We tested competing causal and non-causal h…

www.sciencedirect.com

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Reposted by Jeremy Elman

VETSA @vetsa.bsky.social · Jul 22

Study by Alex Posis finding that TBI is associated with altered microstructure of certain WM tracts that may persist at least 4 decades after the injury.

www.sciencedirect.com/science/arti...

Associations of history of traumatic brain injury with markers of brain health among older men in the Vietnam Era Twin Study of Aging

Traumatic brain injury (TBI) is associated with increased risk of dementia, but it is unclear how earlier life TBI is related to brain health in older…

www.sciencedirect.com

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Reposted by Jeremy Elman

Rongxiang (Catherine) Tang @rongxiang.bsky.social · Jul 22

Happy to share a new published study link.springer.com/article/10.1...
on subjective memory concern, negative affect, and cortical microstructure using @vetsa.bsky.social dataset and supported by a K01 grant from the NIA!

link.springer.com

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Reposted by Jeremy Elman

Jake Vogel @jwvogel.bsky.social · Jul 22

‼️NEW PREPRINT‼️

What if you could take a normal 3T T1w MRI and make it look like it was acquired from a 7T scanner?

That's exactly what we do using AI in our new preprint!

Link: arxiv.org/abs/2507.13782

#neuroskyence #neurosky #compneuro #AI #datascience #neurology #mrisky #neuroimaging

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Reposted by Jeremy Elman

Jake Vogel @jwvogel.bsky.social · Jul 17

Incredibly excited for this new work from our lab. We test the potential of AI-based neurodegenerative disease diagnostics using plasma proteomics data from n>17,000 people, led by the brilliant and indefatigable @anlijuncn.bsky.social Check it out!👇

Lijun An @anlijuncn.bsky.social · Jul 15

Can AI reveal risk & co-pathology of multiple neurodegenerative diseases from a single blood sample? We explored AI-based diagnostic power on high rank plasma proteomics (N=17,170). www.medrxiv.org/content/10.1... #neuroskyence #neurosky #Alzheimer #compneuro #AI #datascience #neurology

Benchmarking the AI-based diagnostic potential of plasma proteomics for neurodegenerative disease in 17,170 people

Co-pathology is a common feature of neurodegenerative diseases that complicates diagnosis, treatment and clinical management. However, sensitive, specific and scalable biomarkers for in vivo pathologi...

www.medrxiv.org

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Jeremy Elman @jaelman.bsky.social · Jul 12

It must be so hard for him in the tech world where, based on his griping, I assume he's usually the only white guy in the room.

Jeremy Elman @jaelman.bsky.social · Jul 11

Tell me again how immigrants are to blame for lack of school funding
www.kpbs.org/news/educati...

Trump administration freezes $50 million in San Diego County public school funding

A federal education grant funding freeze is affecting many school districts across San Diego County. Millions of dollars of public school funding are in limbo.

www.kpbs.org

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Jeremy Elman @jaelman.bsky.social · Jul 9

Big caveat: Although it does what I need it to, this is essentially 100% AI created so YMMV. Github repo below if you'd like to modify or build a local app. Hope it's useful!

github.com/jelman/TreeF...

GitHub - jelman/TreeForge: A modern web-based application for creating, editing, and visualizing folder structures with drag-and-drop functionality

A modern web-based application for creating, editing, and visualizing folder structures with drag-and-drop functionality - jelman/TreeForge

github.com

Jeremy Elman @jaelman.bsky.social · Jul 9

With TreeForge you can:
1. Drag and drop folders/files in a visual editor
2. Toggle between markdown (for easier editing) and ASCII (for better visualization) in a text editor
3. Edits sync across windows
3. Import/export JSON and ASCII files to send to others and for data documentation.

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Jeremy Elman @jaelman.bsky.social · Jul 9

Trying to create directory tree for a new project or storage location? I did, but couldn't find an app that did exactly what I wanted, so I had GitHub Copilot + Claude create an app for me.

Link to the web app: jelman.github.io/TreeForge/

Screenshot of the TreeForge web app with visual editor on the left and text editor on the right

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Jeremy Elman @jaelman.bsky.social · Jun 14

The onslaught of 2025 can be so isolating. Today was a really great reminder that we're a community, and a large one at that.

Scott Dworkin @dworkin.bsky.social · Jun 14

San Diego #NoKings

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Jeremy Elman @jaelman.bsky.social · Jun 2

I'm so sorry Heidi, that is truly awful news. The work you and your colleagues do is necessary and important, and we are all worse off for this. If there is anything I can do, please reach out.

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Reposted by Jeremy Elman

Emilie Reas @etreas.bsky.social · Jun 2

New work from our postdoc Seraphina Solders shows patterns of blood-brain barrier leakage in cognitively normal APOE4 carriers. BBB breakdown correlated with microstructural brain injury only in groups with high Alzheimer's disease risk (APOE4+, amyloid+, women) www.sciencedirect.com/science/arti...

Blood-brain barrier permeability varies by brain region and APOE4 status and correlates with brain microstructure among high-AD risk groups

Although strong evidence exists for blood–brain barrier (BBB) disruption in Alzheimer’s disease (AD), substantial uncertainty remains regarding its ro…

www.sciencedirect.com

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Jeremy Elman @jaelman.bsky.social · Jun 1

Everything about this was intended to provoke a response. They wouldn't have brought that show of force to that restaurant on that corner on a Friday evening if they didn't want to attract attention.

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Jeremy Elman @jaelman.bsky.social · May 31

This is a popular neighborhood restaurant on a corner with a lot of foot traffic. Rolling in like this on a Friday evening could only have been meant to send a message. It was guaranteed to be packed with folks from the neighborhood, including kids. No wonder they cover their faces.

LorennaCleary.bsky.social @lorennacleary.bsky.social · May 31

San Diego erupts at ICE raiding a local restaurant and detaining ALL staff.

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Reposted by Jeremy Elman

Dr. Donna Wilcock @wilcocklab.bsky.social · Apr 28

Thank you @60minutes.bsky.social for giving the NIH freezes, termination, and proposed budget cuts the attention they deserve. ALL Americans, regardless of party, will feel this impact to their health far beyond one administration. www.cbsnews.com/video/nih-cu...

Federal cuts to National Institutes of Health could threaten medical progress

Former National Institutes of Health Director Dr. Francis Collins, who abruptly left his NIH research lab in February, fears aggressive downsizing could impact Americans’ health.

www.cbsnews.com

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Jeremy Elman @jaelman.bsky.social · Apr 13

Although I suppose he would also consider this to be the desired outcome...

Jeremy Elman @jaelman.bsky.social · Apr 13

Is he unaware that, at least in schools of medicine, there has been a huge shift towards soft money positions? This is presumably the type of move he would support, even though we are seeing right now how this type of system leaves people vulnerable to the whims of the Executive branch.

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Josh Gondelman @joshgondelman.bsky.social · Apr 13

This Passover I’m thinking hard about the holiday’s history of resistance to tyrannical leaders, and the imperative for Jewish people to stand with all oppressed peoples of the world.

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