Please do not hesitate to reach out directly with questions or for more information. Additional data such as raw MRI images in BIDS format and composite variables are also available upon direct request. Visit our website below for more information.
psychiatry.ucsd.edu/research/pro...

🚨NEW DATA RELEASE🚨

Data from VETSA waves 1-3 is now available for public download from NACDA! This includes cognitive, health, psychosocial and demographic info from our nationwide twin cohort. Future releases will include wave 4 data and derived MRI variables.
www.icpsr.umich.edu/web/ICPSR/st...

Excited to share my new K01 work to understand chronic pain as an AD risk factor - a collaboration of the VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social and Rush Medical University using the ROSMAP data. academic.oup.com/braincomms/a...

Excited to share my new study with the
VETSA team (vetsa.bsky.social) with jaelman.bsky.social and matthewpanizzon.bsky.social published in #JINS showing that moderate-to-severe chronic pain and opioid use are independently related to risk of mild cognitive impairment. tinyurl.com/y88k5z4j

Study from Nathan Gillespie testing causal associations of plasma amyloid on total tau using #VETSA twin data.
www.sciencedirect.com/science/arti...

Study by Alex Posis finding that TBI is associated with altered microstructure of certain WM tracts that may persist at least 4 decades after the injury.

www.sciencedirect.com/science/arti...

Happy to share a new published study link.springer.com/article/10.1...
on subjective memory concern, negative affect, and cortical microstructure using @vetsa.bsky.social dataset and supported by a K01 grant from the NIA!

*Posted for McKenna Williams, not yet on BlueSky*

Our new paper on cognitive resilience against Alzheimer’s pathology is out now!

onlinelibrary.wiley.com/doi/full/10....

We found around 1.31% of childhood disadvantage effects on later life GCA were mediated by SA profile. Specifically, childhood disadvantage was related to more deviation of the cortical SA spatial patterning from the normative cortical organizational principle, which in turn was linked to lower GCA.

Specifically, the profile is the extent to which the spatial patterning of SA deviates from the normative unimodal–transmodal cortical organization as defined by the principal gradient (Margulies et al., 2016).

Although total SA has been linked to lifespan GCA differences, total SA does not capture the nonuniform nature of childhood disadvantage effects on neuroanatomy (e.g., different across unimodal and transmodal cortices). To address this, we created a novel metric—cortical SA profile.

New article led by @rongxiang.bsky.social examining the effects of childhood disadvantage on late midlife cortical surface area (SA) profile and general cognitive ability (GCA). Cortical SA was found to be the mediator of childhood disadvantage-GCA association.
academic.oup.com/psychsocgero...

New article led by @cfnote.bsky.social and Shu-Ju Lin describing a novel parcellation of abnormal white matter w/ 5 distinct regions. Twin models identified common & unique genetic and environmental influences that may reflect variable underlying etiologies.
onlinelibrary.wiley.com/doi/10.1002/...