James King
@jamesking.io
23 followers 63 following 20 posts
Digital product designer from London. Founder at https://science-practice.com and co-founder at https://fora.health. Contributor to the Ergodicity Economics research community. https://jamesking.io
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Reposted by James King
davidsacerdote.bsky.social
A decade after it was written, I find myself pulling out the @cingraham.bsky.social's gerrymandering explanation to help people understand why California’s Prop. 50 is so important to pass.

wapo.st/3WfcjeB
This is the best explanation of gerrymandering you will ever see
By simplifying gerrymandering we see how problematic it really is.
wapo.st
jamesking.io
Enjoyed this video from @tantacrul.bsky.social about the design and engineering of the new version of Audacity (open source audio software). Beautifully explained and produced. This link is to the last section, but whole video is great. youtu.be/QYM3TWf_G38?...
How We're Redesigning Audacity For The Future
YouTube video by Tantacrul
youtu.be
jamesking.io
Side note: I really hope Aaron Sorkin and the writers of Silicon Valley are sharpening their pencils. There is so much material here.
jamesking.io
Latest episode of Acquired is great! It’s a recent history of Google’s successes and failures on AI, but covers most of the main players like OpenAI, Anthropic and others along the way. It’s 4 hours long, like all good podcasts should be. www.acquired.fm/episodes/goo...
Google: The AI Company | Acquired Podcast
The complete podcast (and transcript!) of Google and Alphabet’s AI history and business strategy.
www.acquired.fm
jamesking.io
Yesterday @aubreyclayton.bsky.social delivered a talk for the Ergodicity Economics seminar series. Aubrey shows how it is possible to derive the equations of probability without linking them to frequencies. A video of the talk is here: ergodicityeconomics.com/2025/10/01/6...
Ergodicity Economics
ergodicityeconomics.com
Reposted by James King
scientificdiscovery.dev
New episode of HARD DRUGS!

AlphaFold, ProteinMPNN & other AI tools are transforming biology and drug design.

But how do they work? What can’t they do? And can we use them to make a vaccine against Strep A for the very first time?

In this episode, Jacob and I talk about hacking proteins with AI.
Hacking proteins with AI
open.spotify.com
jamesking.io
Just spotted that this was shared in the @observablehq.com newsletter. Nice!
jamesking.io
Big fan of @observablehq.com and since their preview release of Observable Notebooks 2.0 my team at Fora Health have integrated Notebook Kit into our app. Works really well so far. Quick demo ⬇️

screen.studio/share/TqvyfFbU
Observable Notebooks 2.0 in Fora Health — Screen Studio
Observable Notebooks 2.0 in Fora Health — Created and shared with Screen Studio
screen.studio
jamesking.io
I'm helping to organise this seminar series. The next seminar will be given by Aubrey Clayton, the author of Bernoulli's Fallacy. Come and join us: ergodicityeconomics.com/event/semina...
Seminar. Aubrey Clayton. “Teaching Probability Without Frequencies” – Ergodicity Economics
ergodicityeconomics.com
Reposted by James King
ocks.org
Observable Notebook Kit & Desktop 1.4 now support TypeScript cells, along with TypeScript for Node.js data loader cells. (Just type stripping, but greatly helps interoperability.)
jamesking.io
Thank you for such an amazing set of tools.
jamesking.io
Big fan of @observablehq.com and since their preview release of Observable Notebooks 2.0 my team at Fora Health have integrated Notebook Kit into our app. Works really well so far. Quick demo ⬇️

screen.studio/share/TqvyfFbU
Observable Notebooks 2.0 in Fora Health — Screen Studio
Observable Notebooks 2.0 in Fora Health — Created and shared with Screen Studio
screen.studio
jamesking.io
New blog post: Failing to reproduce Axelrod, 1980

Today I learned that a foundational result in game theory hasn’t been successfully reproduced, and not from lack of trying.

jamesking.io/2025/09/02/f...
Failing to reproduce Axelrod, 1980 | James King
jamesking.io
jamesking.io
This thread is a really good short summary/review of the Unaccountability Machine by Dan Davies.
nikvenkatesh.bsky.social
I enjoyed this very much - thanks for writing it @dsquareddigest.bsky.social !
The front cover of a book: "The Unaccountability Machine: why big systems make terrible decisions" by Dan Davies
jamesking.io
You can add more than 1 to a prompt and use them as inline references. That’s really nice.
jamesking.io
Oh wow! That’s really useful! Thanks for the tip
Reposted by James King
ocks.org
Notebooks 2.0 is here! 📓🔮 Previewing today:
Notebook Kit, an open file format for notebooks with open-source tooling for generating static sites; and
Observable Desktop, a macOS desktop application for editing notebooks as local files, with a radical new approach to AI. observablehq.com/notebooks/2/
Observable Notebooks 2.0 Technology Preview | Observable
observablehq.com
jamesking.io
Beautiful cover!
jamesking.io
It’s the Aquired podcast format applied to drug discovery. That’s a very good thing.
scientificdiscovery.dev
LAUNCH DAY 🚀

Today I’m launching a new podcast, Hard Drugs, with Jacob Trefethen (@jacobtref.bsky.social)

Our first episode is about lenacapavir — a new HIV drug that blocks infections with an efficacy rate of nearly 100%, and which could completely change the fight against HIV worldwide.
Lenacapavir: The miracle drug that could end AIDS
Hard Drugs · Episode
open.spotify.com
Reposted by James King
dingdingpeng.the100.ci
Excellent video on whether retinol is a scam — there are only few low quality RCTs, why would one still believe in it? — and it’s so good, talking about various incentives and the role of mechanistic knowledge. I’ll have to think about how to fit this into teaching!>
m.youtube.com/watch?v=e6Z5...
Does retinol in skincare even work?
YouTube video by Lab Muffin Beauty Science
m.youtube.com
jamesking.io
@mmtpodcast.bsky.social your intro to MMT at the start of the latest episode was excellent. Such a good distillation. 👏