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Reposted by Jan Nolta, PhD

HemeHub @hemehub.bsky.social · 4d

This Month on HemeHub: SCD and Gene Therapy

Join us as we explore advances in the treatment of #sicklecelldisease through #genetherapy, featuring pivotal trials of Lyfgenia and Casgevy.

Stay tuned for our upcoming session featuring Dr. John Tisdale, Senior Investigator at the NHLBI.

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Reposted by Jan Nolta, PhD

Daniah Beleford @daniahbeleford.bsky.social · 7d

basicscience.ucdmc.ucdavis.edu/beleford-lab...

Opportunities | Beleford Lab

basicscience.ucdmc.ucdavis.edu

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Jan Nolta, PhD @jannolta.bsky.social · 14d

Congratulations to ⁦‪UniQure and to the #huntingtonsdisease community! 💙💜

www.uniqure.com/investors-me...

Press Releases | Investors & Media

Reimagining the future of healthcare through the power of gene therapy.

www.uniqure.com

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Reposted by Jan Nolta, PhD

BioInformant - Stem Cell Industry News @bioinformant.bsky.social · 19d

AABB’s Cell and Gene Therapy Standards for Pharmacy, First Edition, Takes Effect October 1 - bioinformant.com/aabbs-cell-a...
@aabbupdates.bsky.social

AABB’s Cell and Gene Therapy Standards for Pharmacy, First Edition, Takes Effect October 1 | BioInformant

Sept 8, 2025, Bethesda, MD – The Association for the Advancement of Blood & Biotherapies (AABB) is pleased to announce the release of the first edition of Cell and Gene Therapy Standards for Pharmacy,...

bioinformant.com

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Jan Nolta, PhD @jannolta.bsky.social · 26d

Congratulations to Brian Fury, our GMP Facility Director at UC Davis Health @ucdavis.bsky.social, and to all of the other recipients of these G-Rex grant awards from ScaleReady.

www.prnewswire.com/news-release...

ScaleReady Awards G-Rex® Grants to Support Cell and Gene Therapy Manufacturing in California

/PRNewswire/ -- ScaleReady, in collaboration with Wilson Wolf Manufacturing, Bio-Techne Corporation (NASDAQ: TECH) and CellReady, today announced that eight...

www.prnewswire.com

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Reposted by Jan Nolta, PhD

UC Davis @ucdavis.bsky.social · Sep 2

UC Davis & @ucsanfrancisco.bsky.social scientists completed a clinical trial on a new cancer drug for pet cats with squamous cell carcinoma. Researchers believe it will also be effective for humans with similar head and neck cancers. Read more about the clinical trial: ucdav.is/46dxcfM

A calico cat looks out from a box with text below stating a new cancer drug could help both cats and people, credited to UC Davis.

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Jan Nolta, PhD @jannolta.bsky.social · 27d

Enjoy the conference! ☺️

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Jan Nolta, PhD @jannolta.bsky.social · 27d

Momentary break for a much-needed palate cleanser. 🫠
Never knew these adorable creatures existed until this moment. (and nope, it is not AI- they are real! 🥰)

Cephalopods Daily @cephalopodsdaily.bsky.social · 28d

Piglet squids (genus Helicocranchia) are a genus of small cranchiids known for their goofy appearance. They have a rather large siphon that make them look like a pig with a snout.

Well I guess with their arms raised up cranchiid style, they look like a pig with a crazy hairdo.

#SQUIDtember

A piglet squid (Helicocranchia sp.) floating in the ocean. Its entire body is translucent and is oriented horizontally. Its limbs being held upwards, making it look like it has crazy hairdo. It has a relatively large siphon that is below its head sticking straight out, making it look like a pig with a snout. The picture is from the side.

Two In situ photographs of the same female piglet squid (Helicocranchia sp.), anterolateral views, from an ROV photographed floating in front of oil pumping equipment in the Gulf of Guinea at a depth of 1015 m. Arrow in upper photograph points to stub of tentacle. The squid is a slightly translucent beige pink. Its limbs being held upwards, making it look like it has crazy hairdo. It has a relatively large siphon that is below its head sticking straight out, making it look like a pig with a snout, especially since the opening is closed in a way that resembles nostrils.

A piglet squid (Helicocranchia sp.) swimming in the ocean. Its limbs are spread out and pointing up, and its mantle is going back. It has black eyes and its siphon is large and going past its head, making it look like a pig with a snout.

A floating piglet squid (Helicocranchia sp.). Its body is completely translucent, except for a single, thin, vertically oriented organ. Its limbs being held upwards, making it look like it has crazy hairdo. It has a relatively large siphon that is below its head sticking straight out, making it look like a pig with a snout

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Jan Nolta, PhD @jannolta.bsky.social · 27d

I am so honored to be a part of this team. Thank you to the NIH for starting up their funding again. Please hang in there, fellow scientists!
health.ucdavis.edu/medical-scho...

Dream team to develop in utero gene editing therapy for a rare neurological genetic disorder

Professor Aijun Wang won a $3.2 million NIH grant to develop a cure to Dup15q syndrome using an in-utero gene editing formula.

health.ucdavis.edu

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Reposted by Jan Nolta, PhD

Gladstone Institutes @gladstoneinst.bsky.social · Aug 5

🚨 NEW PUBLICATION 🚨 "Human brain vascular multi-omics elucidates disease-risk associations"

www.cell.com/neuron/abstr...

@ucsanfrancisco.bsky.social
@madiganreid.bsky.social
@cellpress.bsky.social

Human brain vascular multi-omics elucidates disease-risk associations

Reid et al. develop MultiVINE-seq to map thousands of non-coding disease variants to genes in human brain vascular cells. Cerebrovascular disease variants compromise vessel integrity, whereas Alzheime...

www.cell.com

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Reposted by Jan Nolta, PhD

International Brain Laboratory @intlbrainlab.bsky.social · 27d

Want to collaborate with the International Brain Laboratory on your own project? We have funding to work with groups anywhere in the world to do new large-scale projects and we are looking for new partners! Learn more and apply: www.internationalbrainlab.com/ibl-core-apply

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Jan Nolta, PhD @jannolta.bsky.social · 27d

House appropriators snub Kennedy, include mRNA vaccine funding in spending bill www.statnews.com/2025/09/10/m... via @statnews.com

House appropriators snub Kennedy, include mRNA vaccine funding in spending bill

Lawmakers have snubbed health secretary RFK Jr. by including an amendment in a spending bill mandating that an agency under his purview continue to research messenger RNA vaccines.

www.statnews.com

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Reposted by Jan Nolta, PhD

Jan Nolta, PhD @jannolta.bsky.social · Aug 10

The regime halted all federal grants then told UC administration if they pay $1 billion they could have them back.
It’s like ransomware.
UC is a public university system and we cannot do this.
So, no grants = no research and labs will shut down.
Are we great yet?

dailybruin.com/2025/08/09/a...

'An attack on knowledge': UCLA researchers say lifesaving research is in jeopardy - Daily Bruin

Dr. Jerzy Kupiec-Weglinski has led organ transplant research at UCLA for nearly three decades. Kupiec-Weglinski, the vice chairman of basic science research in the David Geffen School of Medicine’s su...

dailybruin.com

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Jan Nolta, PhD @jannolta.bsky.social · Aug 10

The regime halted all federal grants then told UC administration if they pay $1 billion they could have them back.
It’s like ransomware.
UC is a public university system and we cannot do this.
So, no grants = no research and labs will shut down.
Are we great yet?

dailybruin.com/2025/08/09/a...

'An attack on knowledge': UCLA researchers say lifesaving research is in jeopardy - Daily Bruin

Dr. Jerzy Kupiec-Weglinski has led organ transplant research at UCLA for nearly three decades. Kupiec-Weglinski, the vice chairman of basic science research in the David Geffen School of Medicine’s su...

dailybruin.com

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Jan Nolta, PhD @jannolta.bsky.social · Aug 5

Trump administration violated impoundment law by canceling NIH grants, slowing new awards, GAO finds www.statnews.com/2025/08/05/g... via @statnews.com

Trump administration violated impoundment law by canceling NIH grants, slowing new awards, GAO finds

The Government Accountability Office found that the Trump administration, by abruptly canceling NIH grants, had violated a 1974 federal law

www.statnews.com

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Jan Nolta, PhD @jannolta.bsky.social · Jul 26

Good morning and happy Saturday. Take a deep breath and keep riding those waves. 🙏

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Reposted by Jan Nolta, PhD

Adam Braithwaite @braithwaiteat.bsky.social · Jul 3

Stimulating immune cells in vitro is a common experimental lab model. We profiled 150K blood immune cells treated with 11 different stimuli to compare the effects. The data are freely available for researchers. See the preprint for our findings and to access the data 🧪 doi.org/10.1101/2025...

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Reposted by Jan Nolta, PhD

Bruce Levine, Ph.D. 🇺🇦 @bllphd.bsky.social · Jul 2

Bioengineered immunocompetent preclinical trial-on-chip tool enables screening of CAR T cell therapy for leukaemia. #Tcell #immunotherapy #organonachip 🧪https://www.nature.com/articles/s41551-025-01428-2

Bioengineered immunocompetent preclinical trial-on-chip tool enables screening of CAR T cell therapy for leukaemia - Nature Biomedical Engineering

An ex vivo organotypic and immunocompetent human leukaemia chip system is used for CAR T cell therapy modelling and screening of patient response.

www.nature.com

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Reposted by Jan Nolta, PhD

KFF Health News @kffhealthnews.org · Jul 9

After spearheading a 34% cut in cancer mortality, the National Cancer Institute at the NIH is bleeding resources and staff and could see its budget cut by nearly 40%. kffhealthnews.org/news/article...

World’s Premier Cancer Institute Faces Crippling Cuts and Chaos - KFF Health News

After spearheading a 34% cut in cancer mortality, the National Cancer Institute at the NIH is bleeding resources and staff and could see its budget cut by nearly 40%.

kffhealthnews.org

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Jan Nolta, PhD @jannolta.bsky.social · Jun 20

www.cnn.com/2025/06/20/p...

Federal judge indefinitely blocks Trump administration from cutting off Harvard’s ability to host foreign students | CNN Politics

A federal judge on Friday indefinitely blocked the Trump administration from revoking Harvard University��s ability to host international students and scholars while legal challenges continue.

www.cnn.com

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Reposted by Jan Nolta, PhD

grumpyoldscientist.bsky.social @grumpyoldscientist.bsky.social · Jun 5

Explore this gift article from The New York Times. You can read it for free without a subscription.

www.nytimes.com/2025/06/05/h...

And this is your new improved FDA. Into everyone’s medical life, a few charlatans must fall.

Kennedy Says ‘Charlatans’ Are No Reason to Block Unproven Stem Cell Treatments

www.nytimes.com

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Reposted by Jan Nolta, PhD

Cell Press @cellpress.bsky.social · May 22

"Specific targeting of brain endothelial cells using enhancer AAV vectors"
www.cell.com/neuron/fullt...

Xiangmin Xu & colleagues
@cp-neuron.bsky.social