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Jason Murphy @jasemurphy.bsky.social · 1h

Mice treated with the new drug (middle column in each group of 9) were way better at building nests than the ones who got the sham treatment (left column). They were more like the "wild type" mice who weren't engineered to have mouse Alzheimers(right column). 🐭

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Jason Murphy @jasemurphy.bsky.social · 2h

News story spells it out nicely. Brains dump all the toxic junk immediately. They found a lot of the amyloid was gone inside an *hour*. And the mice were like young mice again 6 months later. www.discovermagazine.com/repairing-th...

Repairing the Blood Brain Barrier Reversed Alzheimer's Disease in Mice, a Hopeful Result for Humans

Merging biophysics with knowledge of how the brain handles waste led to an impressive 50 percent reduction of amyloid beta in mice brains and restoration of cognitive function.

www.discovermagazine.com

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Jason Murphy @jasemurphy.bsky.social · 2h

Something super hopeful:
A way to treat Alzheimers that is totally new and was just shown to work amazingly in mice.

Rapid amyloid-β clearance and cognitive recovery through multivalent modulation of blood–brain barrier transport | share.google/U23UhLehCUUC...

Rapid amyloid-β clearance and cognitive recovery through multivalent modulation of blood–brain barrier transport - Signal Transduction and Targeted Therapy

Signal Transduction and Targeted Therapy - Rapid amyloid-β clearance and cognitive recovery through multivalent modulation of blood–brain barrier transport

share.google

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Reposted by Jason Murphy

Crikey @crikey.com.au · 9d

Rice, lentils, oats and frozen vegetables will get you a long way. But even this menu assumes luxuries that people experiencing poverty simply cannot access, @jasemurphy.bsky.social writes.

Could you eat for a week for $50?

www.crikey.com.au

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Jason Murphy @jasemurphy.bsky.social · 12d

New PB at Aldi! No special buys but a few bottles of booze.

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Jason Murphy @jasemurphy.bsky.social · 12d

Tomorrow I'm doing that.

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Jason Murphy @jasemurphy.bsky.social · 12d

I did over 15000 days in a row the same: I ate things. And then, bam. I **stopped**.
Trying #fasting.
3 days in, it's not impossible but still, awful! Here's to another 15000 back in the old mode!

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Jason Murphy @jasemurphy.bsky.social · 13d

#aflgf post.
I forecast a day where the half-time kick-to-kick stretches out for the neutrals: the Cats will have all but buried them by half time.
A few consolation goals and let's say a 33 point final margin. #aflcatslions #GoCats

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Jason Murphy @jasemurphy.bsky.social · 13d

Which would mean using supermarket checkout data not surveys on tobacco purchases.

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Jason Murphy @jasemurphy.bsky.social · 13d

No the basket is weighted! I agree they should measure only legal tobacco sales if they want to be fair and consistent with drugs

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Jason Murphy @jasemurphy.bsky.social · 13d

The ABS is opposed but if those things become a big enough factor imo they should!

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Jason Murphy @jasemurphy.bsky.social · 14d

(confounder: I stop exercising when things get hard, but I promise my future self that next time this happens I'll drop something*else* and not the silver thread holding together my mental well-being!)

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Jason Murphy @jasemurphy.bsky.social · 14d

What should be different is we should not let organized crime run amok in a booming market!!

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Jason Murphy @jasemurphy.bsky.social · 14d

CPI measures what Australians buy. They should be in there!

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Jason Murphy @jasemurphy.bsky.social · 14d

There's heavy philosophy about the path to happiness but for me the recipe is just embarrassingly *corporeal*.
A tendency to joy transforms to existential despair if I simply. stop. exercising.

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Jason Murphy @jasemurphy.bsky.social · 14d

Smokes are not the biggest contributor to the CPI, but for such a small component of the basket they weigh heavily, because the official price keeps rising so quickly. Total CPI was up 1 percentage points, of which .06 was tobacco price rise. 2/2 🚬

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Jason Murphy @jasemurphy.bsky.social · 14d

Regular reminder: Australia's inflation data is overstated because they sample the price of legal cigarettes, which are up 12 per cent. And not the cigarettes people buy, which are cheaper than they have been for a decade. #ausecon 1/2

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Jason Murphy @jasemurphy.bsky.social · 14d

It's run for shareholders but those big financial firms are not the true owners, they hold the shares for the true owners (pension funds, hedge funds etc) . These lists are always tripping people up! www.smh.com.au/politics/fed...

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Reposted by Jason Murphy

Tom Flood @tomflood.bsky.social · Sep 5

Shared Responsibility.

@thebikinglawyer.bsky.social

black car with a red x and a bright yellow car with a green check mark.
It's getting dark out earlier, be sure to add a bright coat of paint to your vehicle. Remember road safety is a shared responsibility.

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Jason Murphy @jasemurphy.bsky.social · 15d

I did not know Oz was associated with iHerb!

Folinic acid though, is miles out of patent, it's just a vitamin (particular form of b9). Thousands of makers, thousands of sellers.

Reposted by Jason Murphy

Tom Kindlon @tomkindlon.bsky.social · 24d

"Mass Psychogenic Illness" at Heathrow Airport-NOT! by David Tuller @davetuller1.bsky.social

virology.ws/2025/09/12/t...

Image is screenshot from latest Science for ME weekly update