Interpreting liver blood test results can be challenging. How should clinicians interpret abnormal results?

New Education articles offers guidance and a visual summary
#BMJInfographic
www.bmj.com/content/391/...

Candidate for Ig Nobel Prize surely?

@cosrh.org has produced a statement on use of GLP-1s & contraception:
- Use contraception
- Add non-oral method for 4 weeks after start or dose increase of TIRZEPATIDE (but not other GLP-1s)
- Follow existing guidance for severe diarrhoea/vomiting
See: buff.ly/TMYUHY4

A letter in the @pharmaj.bsky.social notes the risk of mis-selection now that there are two posaconazole suspension: 30mg/mL gastro-resistant and 40mg/mL plain, which are not interchangeable. What is worse is that there are generics of 40mg/mL, so risk is unlikely to be short-term.
buff.ly/45wlLd4

(1/4) A new Tan-Yang Center for Autism Research study published in the Journal of Autism and Developmental Disorders from researchers identifies the top ways workplaces can be made more inclusive for autistic employees.

Nonprofit org Neurodiversity in the Workplace also supported the study.

Antidepressants differ significantly in their effects on body mass and other cardiometabolic measures, a review has found.

Read more on MIMS:

When used carefully, social media can be a powerful tool for doctors to advocate for important causes, use their voices positively, and engage with the public.

Errors in judgment, however, can be costly, writes Sabira Hughes @medicalprotection.bsky.social

www.bmj.com/content/391/...

Join our PROMPPT webinar for expert insight to help reduce opioid use for patients in persistent pain.

Sign up her and join us 1-2pm on 4 Nov: https://prescqipp.info/our-resources/clinical-webinars/promppt-a-practice-pharmacist-led-review-for-patients-who-are-prescribed-opioids-for-persistent-pain/

#BBCNews reports @uniofsurrey.bsky.social developed a label that changes colour to flag if a product has been stored above the recommended temperature. If it tracks amount of time, not just max temp, this could be game-changing for drug storage/stability.

When psoriasis treatment fails, switching biologics can help. A review showed varied effectiveness and safety outcomes. PMID:40768223, JAMA Dermatol 2025 https://doi.org/10.1001/jamadermatol.2025.2714 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Hopefully when trial protocols stop using it too! CrCl is inaccurate, but if it's baked into the study data, are we stuck with it?

Nice review on the superior accuracy of race-free eGFR here: doi.org/10.1093/ajhp...

How good is #AI? The worst it's ever going to be. ChatGPT-5 hallucinates less than 4o. So if you're looking at research on using AI, the really old stuff (like six months ago!) may not reflect current capability. See openai.com/index/introd...