What's your sense of how many genes are affected by this mechanism? It seems this could in principle act on heterozygous LoF mutations to upregulate the second copy of the *same* gene. But I don't think that can be a strong & widespread effect, based on LoF analyses that we have done over the years.

Thanks for sharing. Very cool paper!

that is so awesome!

Looks like some kind of shield bug. Stick it on iNaturalist.
en.wikipedia.org/wiki/Pentato...

Congratulations!

Thanks for pointing us to your paper! cc: @nikhilmilind.dev @peter-gerlach.bsky.social

thanks, that's very kind of you to say!