Johansen B Amin MD PhD
@johansenb.bsky.social
Hi there! I’m a psychiatrist with a research hobby/obsession. I work with a lot of ideas of scale, from molecular biophysics to social dynamics. I keep my feed active, so say hello! Happy to chat!
Trump’s administration fired 1500 NIH employees along with thousands from related agencies. The loss of experience and knowledge is incalculable.
Many scientists in my lab came to the US to avoid authoritarianism.
They all say the same thing:
“I can’t believe this is happening here”
Many scientists in my lab came to the US to avoid authoritarianism.
They all say the same thing:
“I can’t believe this is happening here”
February 18, 2025 at 12:44 AM
Trump’s administration fired 1500 NIH employees along with thousands from related agencies. The loss of experience and knowledge is incalculable.
Many scientists in my lab came to the US to avoid authoritarianism.
They all say the same thing:
“I can’t believe this is happening here”
Many scientists in my lab came to the US to avoid authoritarianism.
They all say the same thing:
“I can’t believe this is happening here”
Reposted by Johansen B Amin MD PhD
Today in @natureportfolio.bsky.social: Research led by Jia Zhou in the Hibbs Lab @ucsandiego.bsky.social resulted in a map of the structures of human brain receptors. The study has implications for understanding signaling in the brain and for treating diseases like epilepsy.
📰 go.ucsd.edu/40lXlF4
📰 go.ucsd.edu/40lXlF4
Epilepsy Patient Samples Offer Unprecedented Insights on Brain ‘Brakes’ Linked to Disorders
Specific protein receptors in the brain play a vital role in how neurons slow down or stop firing, making them targets for many disorders. Researchers have now constructed a detailed structural map of...
go.ucsd.edu
January 22, 2025 at 10:35 PM
Today in @natureportfolio.bsky.social: Research led by Jia Zhou in the Hibbs Lab @ucsandiego.bsky.social resulted in a map of the structures of human brain receptors. The study has implications for understanding signaling in the brain and for treating diseases like epilepsy.
📰 go.ucsd.edu/40lXlF4
📰 go.ucsd.edu/40lXlF4
We made neurons from patients with bipolar disorder who either responded to lithium, or didn’t. Synapses
from patients that did respond to lithium had more of a key protein that tells us a lot about why lithium stabilizes mood.
Free access link in comments!
www.sciencedirect.com/science/arti...
from patients that did respond to lithium had more of a key protein that tells us a lot about why lithium stabilizes mood.
Free access link in comments!
www.sciencedirect.com/science/arti...
Synaptic protein expression in bipolar disorder patient-derived neurons implicates PSD-95 as a marker of lithium response
Bipolar disorder (BD) is a severe mental illness characterized by recurrent episodes of depression and mania. Lithium is the gold standard pharmacothe…
www.sciencedirect.com
January 23, 2025 at 4:20 PM
We made neurons from patients with bipolar disorder who either responded to lithium, or didn’t. Synapses
from patients that did respond to lithium had more of a key protein that tells us a lot about why lithium stabilizes mood.
Free access link in comments!
www.sciencedirect.com/science/arti...
from patients that did respond to lithium had more of a key protein that tells us a lot about why lithium stabilizes mood.
Free access link in comments!
www.sciencedirect.com/science/arti...
Reposted by Johansen B Amin MD PhD
Reposting for the Science feed: 🧪
“Until we acknowledge that publish or perish is the natural consequence of the rankings obsession, we’re not going to fix anything.”
www.nature.com/articles/d41...
www.nature.com/articles/d41...
‘Publish or perish’ culture blamed for reproducibility crisis
Survey of more than 1,600 biomedical researchers also flagged small sample sizes and cherry-picking of data as leading causes of reproducibility problems.
www.nature.com
January 20, 2025 at 11:57 PM
Reposting for the Science feed: 🧪
Reposted by Johansen B Amin MD PhD
Our January issue is here ✨ https://buff.ly/3DFIr4N The cover shows agonist-induced #ionchannel opening of human NMDA receptors assayed using single channel outside-out patches to detect varied activation delays and failures. From Miaomiao He & @lwollmuth.bsky.social (https://buff.ly/3W6IQ6J).
January 6, 2025 at 3:04 PM
Our January issue is here ✨ https://buff.ly/3DFIr4N The cover shows agonist-induced #ionchannel opening of human NMDA receptors assayed using single channel outside-out patches to detect varied activation delays and failures. From Miaomiao He & @lwollmuth.bsky.social (https://buff.ly/3W6IQ6J).
When your doctor asks you what your symptoms are, they treat your symptoms.
However, when your doctor asks you what your life goals are, they treat you in a way that optimizes your attainment of said goals, symptoms be damned.
That is what Recovery means.
academic.oup.com/schizophreni...
However, when your doctor asks you what your life goals are, they treat you in a way that optimizes your attainment of said goals, symptoms be damned.
That is what Recovery means.
academic.oup.com/schizophreni...
Recovery-Oriented Principles Provide a Dynamic Reframing of Patient Care in Schizophrenia
Since the mid-20th century, the treatment of schizophrenia has shifted from the institutional setting to the community care setting.1 Older treatment model
academic.oup.com
January 20, 2025 at 11:59 PM
When your doctor asks you what your symptoms are, they treat your symptoms.
However, when your doctor asks you what your life goals are, they treat you in a way that optimizes your attainment of said goals, symptoms be damned.
That is what Recovery means.
academic.oup.com/schizophreni...
However, when your doctor asks you what your life goals are, they treat you in a way that optimizes your attainment of said goals, symptoms be damned.
That is what Recovery means.
academic.oup.com/schizophreni...
Did you know there are identical twins where one has schizophrenia and the other doesn’t? Why?
This paper suggests their neurons have the same genes, but’s express them differently, and compensate at a network level, take a look:
www.nature.com/articles/s41...
This paper suggests their neurons have the same genes, but’s express them differently, and compensate at a network level, take a look:
www.nature.com/articles/s41...
Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission - Molecular Psychiatry
Molecular Psychiatry - Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission
www.nature.com
December 16, 2024 at 11:21 PM
Did you know there are identical twins where one has schizophrenia and the other doesn’t? Why?
This paper suggests their neurons have the same genes, but’s express them differently, and compensate at a network level, take a look:
www.nature.com/articles/s41...
This paper suggests their neurons have the same genes, but’s express them differently, and compensate at a network level, take a look:
www.nature.com/articles/s41...
Consider what happens when your doctor treats you based on what your goals are and not what your symptoms are.
Especially in severe mental illness, this is the difference between helplessness and empowerment.
pubmed.ncbi.nlm.nih.gov/39016199/
Especially in severe mental illness, this is the difference between helplessness and empowerment.
pubmed.ncbi.nlm.nih.gov/39016199/
Recovery-Oriented Principles Provide a Dynamic Reframing of Patient Care in Schizophrenia - PubMed
Recovery-Oriented Principles Provide a Dynamic Reframing of Patient Care in Schizophrenia
pubmed.ncbi.nlm.nih.gov
November 25, 2024 at 8:02 PM
Consider what happens when your doctor treats you based on what your goals are and not what your symptoms are.
Especially in severe mental illness, this is the difference between helplessness and empowerment.
pubmed.ncbi.nlm.nih.gov/39016199/
Especially in severe mental illness, this is the difference between helplessness and empowerment.
pubmed.ncbi.nlm.nih.gov/39016199/
This is north of mission beach in San Diego. Really lovely this time of year.
November 24, 2024 at 2:18 AM
This is north of mission beach in San Diego. Really lovely this time of year.
Some posts a about molecular psychiatry… coming soon :)
November 24, 2024 at 2:16 AM
Some posts a about molecular psychiatry… coming soon :)