Júlio Souza dos-Santos
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juliosds1.bsky.social
Júlio Souza dos-Santos
@juliosds1.bsky.social
170 followers 50 following 7 posts
Postdoctoral associate, Stony Brook University, Department of Microbiology and Immunology 🇺🇸. Ph.D., Immunology from Rio 🇧🇷
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Reposted by Júlio Souza dos-Santos
forum-gd.bsky.social
Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice

#gdTcells @natcomms.nature.com
Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice - Nature Communications
Sepsis-associated encephalopathy (SAE) is a severe and often fatal consequence of sepsis. Here authors show in a mouse model of sepsis that γδ T17 cells, migrating from the small intestine to the meni...
www.nature.com
July 28, 2025 at 9:52 AM
Reposted by Júlio Souza dos-Santos
labwaggoner.bsky.social
Restriction of innate Tγδ17 cell plasticity by an AP-1 regulatory axis @natimmunol.nature.com
www.nature.com/articles/s41...
June 27, 2025 at 6:20 PM
juliosds1.bsky.social
So inspiring 👏🏽👏🏽👏🏽
payalyokota.bsky.social Payal Yokota @payalyokota.bsky.social · May 23
Brilliant end, as expected, by Bruno and (as usual) making room for broader conversations while carefully analyzing all the granular findings.. and making room for future directions and necessary research. @bsilvasantos.bsky.social @eberlmat.bsky.social
May 23, 2025 at 4:56 PM
Reposted by Júlio Souza dos-Santos
payalyokota.bsky.social
The unparalleled @bsilvasantos.bsky.social concludes the amazing #gammadeltatoronto with the keynote talk. A moment I've waited for since may2022 inaugural #gdtcellclub talk.

Super excited to see the wrap up for the unbelievable conf thanks to JC and the other fellow organizers.

Let's go!!
May 23, 2025 at 4:08 PM
Reposted by Júlio Souza dos-Santos
payalyokota.bsky.social
Join us for the 11th Intnl #GDTcells conf in Toronto (May 20-23) as we celebrate emerging research and inspire future directions. I will be wearing two hats: conf organizer and repping #GDTcellclub w/ @eberlmat.bsky.social. Pls come say hi! @forum-gd.bsky.social
na.eventscloud.com/website/7048...
May 14, 2025 at 9:56 PM
Reposted by Júlio Souza dos-Santos
cp-trendsparasitol.bsky.social
Drs @juliosds1.bsky.social & Herbert Leonel de Matos Guedes review #γδTcells in #leishmaniasis: intrinsic factors & outcomes. #Leishmania #Lipophosphoglycan #IL17 #Neutrophil #IFNγ@ufrjoficial.bsky.social @oficialfiocruz.bsky.social

authors.elsevier.com/a/1ktAi5Eb1x...
April 4, 2025 at 4:04 PM
Reposted by Júlio Souza dos-Santos
edelblumlab.bsky.social
📚NEW #gdTcell PAPER ALERT! Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis | Science Immunology
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis
Multiple layers of γδ IEL dysregulation and loss of their immunosuppressive capacity occur before the onset of chronic ileitis.
www.science.org
March 21, 2025 at 6:14 PM
Reposted by Júlio Souza dos-Santos
forum-gd.bsky.social
Signature cytokine-associated transcriptome analysis of effector γδ T cells identifies subset-specific regulators of peripheral activation

#gdTcells @natureportfolio.bsky.social
Signature cytokine-associated transcriptome analysis of effector γδ T cells identifies subset-specific regulators of peripheral activation - Nature Immunology
Here, the authors use a double-reporter system to tag IFNγ-producing versus IL-17A-producing γδ T cells to compile a trancriptomic resource of these cell subsets in mice at steady state and in respons...
www.nature.com
January 30, 2025 at 11:34 AM
Reposted by Júlio Souza dos-Santos
standupforscience.bsky.social
Welcome to the Bluesky account for Stand Up for Science 2025!

Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!

#scienceforall #sciencenotsilence
February 12, 2025 at 5:04 PM
Reposted by Júlio Souza dos-Santos
immunosketch.bsky.social
Some immune cells fuel the fire of disease, while others help put it out—finding the balance could change treatments.

@juliosds1.bsky.social

t.co/8HpBNRQ9Wv
#ImmunoSky 🧪
December 21, 2024 at 4:29 PM
juliosds1.bsky.social
I’m proud to finish my PhD story on a high note. My paper is now published @jlb_journal , where we highlight the IL-17/IFN-γ dichotomy in γδ T cells during L. amazonensis infection. #gdTcells #LoveStory #Science

academic.oup.com/jleukbio/adv...
IL-17A/IFN-γ producing γδ T cell functional dichotomy impacts cutaneous leishmaniasis in mice
Under steady-state conditions, γδ T cell expansion is minimal; however, upon infection with L. amazonensis, there is a marked increase in IL-17-producing γ
academic.oup.com
December 17, 2024 at 1:19 AM
Reposted by Júlio Souza dos-Santos
forum-gd.bsky.social
Elotuzumab-mediated ADCC with Th1-like Vγ9Vδ2 T cells to disrupt myeloma–osteoclast interaction

#gdTcells #ImmunoSky

onlinelibrary.wiley.com/doi/10.1111/...
Elotuzumab‐mediated ADCC with Th1‐like Vγ9Vδ2 T cells to disrupt myeloma–osteoclast interaction
Signaling lymphocytic activation molecule family 7 (SLAMF7), an important therapeutic target of myeloma cells, is highly expressed in osteoclasts. Ex vivo-expanded human Vγ9Vδ2 T cells are able to ef...
onlinelibrary.wiley.com
November 19, 2024 at 11:43 AM
Reposted by Júlio Souza dos-Santos
forum-gd.bsky.social
Please join us for our November #GDTcellclub #gdTcells webinar with talks by Drs. Pamela Ohashi and Anna Ruta.

Nov 21 @ 12pm (New York) | 5pm (London)

mit.zoom.us/j/9351906959...
Zoom ID: 935 1906 9595
Passcode: 292773
November 18, 2024 at 4:10 PM
Reposted by Júlio Souza dos-Santos
gamonasterioo.bsky.social
Coffee-associated beneficial health effects could be due to its influence on intestinal Lawsonibacter asaccharolyticus abundance.

☕️ ☕️ ☕️

www.nature.com/articles/s41...
Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts - Nature Microbiology
Coffee consumption is associated with the presence and abundance of a specific member of the human gut microbiome, Lawsonibacter asaccharolyticus, and changes to the plasma metabolome.
www.nature.com
November 18, 2024 at 10:54 PM
Reposted by Júlio Souza dos-Santos
forum-gd.bsky.social
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November 16, 2024 at 12:20 AM