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Justin J. Taylor, PhD @justintaylorlab.bsky.social · 20h

Functional link here: www.biorxiv.org/cgi/content/...

A searchable database of publications using fluorescent probes and flow cytometry to study antigen-specific B cells

The study of antigen-specific B cells has resulted in important advances in all fields of immunology, the development of experimentally and/or clinically useful antibodies, and as a starting point for...

www.biorxiv.org

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Justin J. Taylor, PhD @justintaylorlab.bsky.social · 23h

All with numerous publications: @jimmunol.bsky.social, @jem.org, @cp-immunity.bsky.social, @cp-cellreports.bsky.social, @sciimmunology.bsky.social, @natimmunol.nature.com, @nature.com, @natcomms.nature.com, @cellpress.bsky.social, @pnas.org, @science.org, @eurjimmunol.bsky.social & @jci.org (4/4)

Justin J. Taylor, PhD @justintaylorlab.bsky.social · 23h

Any thoughts on where to submit the overview? Papers in the database are in over 100 different journals, with the ones next in the thread being the most frequently found (3/4)

homer simpson from the simpsons is standing in a doorway with his arms crossed and the words `` thoughts ? ''

Alt: homer simpson from the simpsons is standing in a doorway with his arms crossed and the words `` thoughts ? ''

media.tenor.com

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Justin J. Taylor, PhD @justintaylorlab.bsky.social · 23h

The database includes work studying hundreds of unique antigens from hundreds of labs. Many thanks to my lab, Scott Chappell from @uvaimmunology.bsky.social , and @koenigjfe.bsky.social for helping build the database. www.immunology.virginia.edu/Taylor/Bcell... (2/4)

www.immunology.virginia.edu

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Justin J. Taylor, PhD @justintaylorlab.bsky.social · 23h

A few years ago, my lab started a list of papers analyzing antigen-specific #Bcells w/ fluorescent probes via #flowcytometry. We are now releasing this list of 700+ papers as a searchable database on my lab website with a short overview. www.biorxiv.org/content/10.1...

Bubble Chart displaying the different types of antigens targeted by B cells in the papers in the database so far. Antigens are grouped into the the viruses, bacteria, parasites, plants, animals, or other sources they come from. And the bubble sizes are scaled to represent how frequently those antigens have been used

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Reposted by Justin J. Taylor, PhD

Adriana Forero @adforu.bsky.social · 8d

We are currently in the process of recruiting a technician. 🥼🐭🔬

If you know anyone with enthusiasm to learn new skills and stamina to hear me go on and on about IFNs, please have them reach out to me for more details!

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Reposted by Justin J. Taylor, PhD

UVA Immunology @uvaimmunology.bsky.social · 15d

Jinyi Tang, PhD, received an NIHK99/R00 grant! The award was issued for Jinyi's work developing mucosal vaccines, which he and the @jie-immunology.bsky.social lab have shown to offer additional protection against COVID-19.

Read more: immunology.virginia.edu/jtang_k99/

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Reposted by Justin J. Taylor, PhD

Waggoner Lab @labwaggoner.bsky.social · 18d

Perspective @cp-immunity.bsky.social A roadmap for defining “extrafollicular” B cell responses
www.cell.com/immunity/ful... @stephanieeisen.bsky.social @vinuesalab.bsky.social et al

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Reposted by Justin J. Taylor, PhD

UVA Immunology @uvaimmunology.bsky.social · Sep 2

CIC Resident Member @immunegirl.bsky.social received an award from the Michael Pascucci Cancer Association to fund her work in engineering T cells against ovarian cancers. Congratulations!

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Reposted by Justin J. Taylor, PhD

UVA Immunology @uvaimmunology.bsky.social · 24d

@jie-immunology.bsky.social lab postdoc Jinyi Tang, PhD, studies immune cell behavior in the lungs after viral infections and mucosal vaccine development. He joined the CIC from the Mayo Clinic in 2021 and recently received a prestigious NIH K99 award! He's also a fan of movies, games, and hiking.

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Reposted by Justin J. Taylor, PhD

Naeha Subramanian @naehasubramanian.bsky.social · Sep 6

We're hiring! Our lab @ISB is looking for a full-time Research Associate to manage our mouse colony 🐭, run experiments in a Type 1 diabetes model, and help keep the lab running smoothly.
Ideal for someone aiming for grad school or further scientific training. isbscience.bamboohr.com/careers/56

Lab Manager I

The Subramanian Lab is seeking a highly motivated and capable Lab Manager I to oversee vivarium operations, manage general lab maintenance and procurement, and contribute directly to research efforts ...

isbscience.bamboohr.com

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Reposted by Justin J. Taylor, PhD

Alison Criss @alisoncrissuva.bsky.social · Aug 29

Incredibly honored to announce I've received an R37 MERIT award to continue our studies on gonococcal-neutrophil interactions. Thank you to the many mentors, colleagues, collaborators, and most importantly, lab members who have contributed to this work!

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Reposted by Justin J. Taylor, PhD

Center for Immunology-UMN @cfi-umn.bsky.social · Aug 25

With deep gratitude, we thank Dr. Marc Jenkins for his decades of leadership, mentorship, and dedication to the Center for Immunology. The foundation he built will guide and inspire us for years to come.

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Reposted by Justin J. Taylor, PhD

Merkel Cell Carcinoma Collaborative (MC3) Institute @mc3-institute.bsky.social · Aug 12

🎉 Thrilled to announce the #NCI has renewed a $14.3M project grant — “Immunobiology & Immune Therapy for Merkel Cell Carcinoma” — led by Dr. Paul Nghiem!

🔗 tinyurl.com/y62adf2f

Funding will support 60 scientists at:
@fredhutch.bsky.social
@uofwa.bsky.social
@uofmichigan.bsky.social
Uni of Virginia

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Justin J. Taylor, PhD @justintaylorlab.bsky.social · Jul 24

Make that 19 out of 19 cases. Whoops!

Justin J. Taylor, PhD @justintaylorlab.bsky.social · Jul 24

All 37 authors from our labs & @mc3-institute.bsky.social were critical for this work, too many to mention here! The project was ultimately led by UW M3D grad student Haroldo Rodriguez, who is co-mentored by Paul and has been visiting @uvaimmunology.bsky.social since the Taylor lab relocated (5/5)

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Justin J. Taylor, PhD @justintaylorlab.bsky.social · Jul 24

This project was started 8 years ago when I was contacted by Paul Nghiem and David Koelle at @uwmedicine.bsky.social and Denise Galloway @fredhutch.bsky.social, who had been studying oncoprotein-specific T cell and antibody responses. And we recruited Josh Veatch's lab along the way (4/5)

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Justin J. Taylor, PhD @justintaylorlab.bsky.social · Jul 24

Overall germinal center and Tfh cell responses did associate with outcome. And human B cells engineered to be specific for oncoprotein potently stimulate human CD4+ T cells specific engineered to express an oncoprotein-specific TCR cloned from a patient sample (3/5)

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Justin J. Taylor, PhD @justintaylorlab.bsky.social · Jul 24

While our tumor sample cohort is small, we could accurately predict disease outcome in 14 of 14 cases by analyzing oncoprotein-specific B cells. In contrast, when we analyzed the much larger populations of B cells in the same samples, this predictive ability is diminished (2/5).

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Justin J. Taylor, PhD @justintaylorlab.bsky.social · Jul 24

Excited to share this preprint of our work studying B cells specific for the oncoprotein driving most cases of Merkel cell carcinoma. While oncoprotein-specific B cells are rare in tumor samples, when we detect robust responses in tumor samples patients do not experience disease progression. (1/5)

bioRxiv Immunology @biorxiv-immuno.bsky.social · Jul 24

B cells specific for polyomavirus-derived oncoprotein are predictive of Merkel cell carcinoma progression https://www.biorxiv.org/content/10.1101/2025.07.22.666002v1

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Reposted by Justin J. Taylor, PhD

Atul Gawande @agawande.bsky.social · Jul 1

STAGGERING: This new study of 133 countries is the first to estimate the impact of all USAID’s work. In 2 decades, it has saved *92M* lives. Current cuts, if not reversed, are forecast to cost up to *14M* lives thru 2030. www.thelancet.com/journals/lan...

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Reposted by Justin J. Taylor, PhD

Jeremy Berg @jeremymberg.bsky.social · Jun 28

Your Saturday dose of anti-science bullshittery...

www.science.org/content/arti...

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Trump cuts subscriptions to Springer Nature journals

Other publishers appear unscathed in recent actions

www.science.org

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Reposted by Justin J. Taylor, PhD

Colette Delawalla @cdelawalla.bsky.social · Jun 27

I feel like this isn’t getting enough attention…because this is CRAZY????

www.nytimes.com/2025/06/27/u... University of Virginia President Resigns Under Pressure From Trump Administration - The New York Times

The Trump administration has privately demanded that the University of Virginia oust its president to help resolve a Justice Department investigation into the school's diversity, equity and inclusion efforts, according to three people briefed on the matter.

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Reposted by Justin J. Taylor, PhD

Jeff Saucerman @jsauce7.bsky.social · Jun 28

Sad to see the Trump admin force resignation of UVA President Ryan. No due process, just hurried political attacks to undermine values of free expression and knowledge on which Thomas Jefferson founded UVA.
www.nytimes.com/2025/06/27/u...

University of Virginia President Resigns Under Pressure From Trump Administration

www.nytimes.com

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Reposted by Justin J. Taylor, PhD

Kai Ryssdal @kairyssdal.bsky.social · Jun 27

Wow. Just wow.

University of Virginia President Resigns Under Pressure From Trump Administration www.nytimes.com/2025/06/27/u...

University of Virginia President Resigns Under Pressure From Trump Administration

www.nytimes.com

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