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Reposted by Naeha Subramanian

ISB @isbscience.org · 2d

Dr. Mary Brunkow is a 2025 Nobel laureate. In today’s @isbscience.org press conference, she shares the FOXP3 story, from a puzzling mouse to a discovery that reshaped immunology.
🎥 Watch the full video: youtu.be/vg61fbycGEk

Mary Brunkow Wins 2025 Nobel Prize | ISB Press Conference (Full)

YouTube video by Institute for Systems Biology

youtu.be

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Sean Gibbons 🦠💩 @gibbological.bsky.social · 2d

Rubbing shoulders with a @nobelprize.bsky.social laureate! 🤩What a week!

Couldn’t have happened to a nicer person: isbscience.org/news/press-r...

@isbscience.org @naehasubramanian.bsky.social @flash-point.bsky.social @annabiosys.bsky.social

Left to right: Sean Gibbons, Naeha Subramanian, Mary Brunkow, Anna Kuchina, and Sid Venkatesh

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Sid Venkatesh @flash-point.bsky.social · 4d

Many congratulations, Mary Brunkow! Couldn’t be happier for you and @isbscience.org ! ♥️

www.nobelprize.org

The official website of the Nobel Prize - NobelPrize.org

The Nobel Prize rewards science, humanism and peace efforts. This is one of the central concepts in the will of Alfred Nobel, and it also permeates the outreach activities that have been developed for...

www.nobelprize.org

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Ram Savan @ramlabuw.bsky.social · 4d

www.nobelprize.org/prizes/medic...

Nobel Prize in Physiology or Medicine 2025

The Nobel Prize in Physiology or Medicine 2025 was awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

www.nobelprize.org

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Science News @scinews.bsky.social · 4d

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

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John Ray @jraylab.bsky.social · 21d

Excited to finally present the lab's latest work in defining candidate causal genetic variants that drive autoimmune diseases and their effects on primary human T cell expression and function! www.nature.com/articles/s41...

Genetic and epigenetic screens in primary human T cells link candidate causal autoimmune variants to T cell networks - Nature Genetics

Massively parallel reporter assay in primary human CD4+ T cells and bulk and single-cell CRISPR-interference screens identify candidate causal variants linked to autoimmune disease risk that modulate ...

www.nature.com

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Ram Savan @ramlabuw.bsky.social · 20d

Pika in the wilderness of Mt. Baker. #pika #pnw #photography #wildlife

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Ram Savan @ramlabuw.bsky.social · 17d

What are you up to? #birds #barredowl #pnw #Seattle #photography

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Itai Yanai @itaiyanai.bsky.social · Sep 7

Legend David Baltimore died yesterday. He understood the way things should work: "the real contribution of MIT is that it doesn't take itself too seriously. It takes ideas seriously, but the people are relatively informal. They are not self-aggrandizing the way academics can be."

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Mark O. Martin @markowenmartin.bsky.social · Sep 7

Please read this wonderful article about my fabulous partner in life, Dr Jennifer Quinn and her work at the Seattle Math Museum! Spread the mathematical joy! @jennifer.j.quinn

www.geekwire.com/2025/seattle...

Seattle’s traveling math magician on why problem-solving matters more than ever in the age of AI

Jenny Quinn, executive director of the Seattle Universal Math Museum, shows off a solved Fibonacci sequence puzzle. (GeekWire Photo / Maddie Stoll) Jenny

www.geekwire.com

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Gc Rox @gcrox.bsky.social · Sep 6

Postdoc position (please re-post)
A funded postdoctoral position, will open in 2026 to study aspects of Neisseria gonorrhoeae pathogenesis, antigenic variation, genetics, or physiology.
If interested in more information, please contact Hank Seifert
[email protected]
#MicroSky

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Naeha Subramanian @naehasubramanian.bsky.social · Sep 6

We're hiring! Our lab @ISB is looking for a full-time Research Associate to manage our mouse colony 🐭, run experiments in a Type 1 diabetes model, and help keep the lab running smoothly.
Ideal for someone aiming for grad school or further scientific training. isbscience.bamboohr.com/careers/56

Lab Manager I

The Subramanian Lab is seeking a highly motivated and capable Lab Manager I to oversee vivarium operations, manage general lab maintenance and procurement, and contribute directly to research efforts ...

isbscience.bamboohr.com

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Maryn McKenna @marynmck.bsky.social · Aug 29

My heart. Members of the US Public Health Service (the uniformed service branch no one has ever heard of, who serve at the CDC and elsewhere in the US), massed within the CDC property, saluting their departing uniformed leaders who were escorted out by security today after resigning on principle.

Isabel @isabelott.bsky.social · Aug 29

A higher resolution pic than my screenshot that captured the salute, from Alyssa Pointer (Reuters) – press weren’t allowed past the front gate for security reasons.

Members of the US Public Health Service Commissioned Corps salute the former officials Wednesday afternoon as staffers gathered outside the CDC's main campus in Atlanta. Alyssa Pointer/Reuters

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The New York Times @nytimes.com · Aug 29

CDC staff held a “clap-out” on Thursday to honor three of the agency’s high-ranking officials, who resigned in protest after President Trump fired the director, Susan Monarez. nyti.ms/4oSxakJ

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Mark Zaid, Esq @markzaidesq.bsky.social · Aug 27

Abbe Lowell and I represent CDC Director #SusanMonarez. Contrary to govt statements, Dr. Monarez has neither resigned nor yet been fired. She will not resign. We have issued the following statement:

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Adam Schwarz @adamjschwarz.bsky.social · Aug 15

“Putin would eat you for lunch.”

Today, exactly that happened.

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Vaughn Cooper @vscooper.micropopbio.org · Jul 30

Let's please keep the remaining staff at NIH, NSF, etc in our thoughts even as you lose sleep over your own lab and scientific career.

They are enduring pure chaos to try to hold the fort.

See snapshot from wapo.st/4feKKuu (gift 🔗) saying they are "barely holding it together"

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Don Moynihan @donmoyn.bsky.social · Jul 30

Shout out to the WSJ journalists who reported on Vought’s impoundment by footnote, causing the White House to walk it back. Impact journalism!!

Liz Essley Whyte @lizessleywhyte.bsky.social · Jul 30

UPDATE: The pause was scrapped Tuesday evening after intervention by top White House officials. www.wsj.com/politics/pol...

Trump Administration Scraps Effort to Pause Health-Research Funding

The administration halted and then restarted billions in new research grants flowing from the National Institutes of Health.

www.wsj.com

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Alexis Battle @alexisbattle.bsky.social · Jul 28

Now up, led by Ashton Omdahl! Our method GLEANR finds shared genetic factors across lots of GWAS, and handles spurious correlation driven by cohort overlap. Neat examples of factors driving related traits with enrichment in different cell types / developmental stages.

The American Journal of Human Genetics @ajhgnews.bsky.social · Jul 28

📣New from @alexisbattle.bsky.social & co!
📄Sparse matrix factorization robust to sample sharing across GWASs reveals interpretable genetic components

Sparse matrix factorization robust to sample sharing across GWASs reveals interpretable genetic components

We developed a computational method to identify genetic pathways shared among complex traits that applies matrix factorization to decompose genetic associations across hundreds of phenotypes. Our meth...

www.cell.com

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BWJones @bwjones.bsky.social · Jul 28

The NIH was healthiest when pay lines were in the 20th percentile range.

We are headed into an environment where pay lines are in the 5% range.

In my entire career, I’ve only had 3 grants that scored better than 5%. And my lab is considered a successful one.

This is going to destroy science.

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Jenna Norton @jenna-m-norton.bsky.social · Jul 26

When we held our rally after the roundtable on Monday to support the #NIH science, we invited Jay Bhattacharya to join us.

He declined saying he was disappointed we “made it political.”

But supporting NIH isn’t partisan! www.politico.com/news/2025/07...

14 Republican senators urge White House to release delayed NIH funds

Sen. Katie Britt (R-Ala.) is leading the letter making the ask of OMB director Russ Vought.

www.politico.com

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Graham Dellaire @docdellaire.bsky.social · Jul 26

Evolutionary molecular biology paying dividends again - this time in finding new modulators of innate immunity - www.science.org/doi/10.1126/...

A human homolog of SIR2 antiphage proteins mediates immunity via the Toll-like receptor pathway

Key actors of mammalian immunity originated from bacterial antiphage systems. The full extent of immune system conservation between bacteria and eukaryotes is unknown. Here, we show that the silent in...

www.science.org

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KF McReynolds @feministscientist.bsky.social · Jul 26

Happy Birthday, Rosalind Franklin. She captured an X-ray diffraction image of DNA and stated that a helical structure was probable. Watson and Crick then created a detailed model based on her results. They initially received credit for the discovery and were awarded the Nobel Prize after her death.🧪

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Jeremy Berg @jeremymberg.bsky.social · Jul 24

Another Bhattacharya email today

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Acyn @acyn.bsky.social · Jul 25

Abughazaleh: I am from one of those families. I do not want Israeli children to live in fear. And I don't want gazan children to starve to death. And there is no enemy of either state that could want me to wish that or excuse the starvation of children. It is that simple.

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