Dr. Tobias Karakach
@karakachlab.bsky.social
Assistant Professor; Scientist; Stoic; Humanist;
Neither an unreasonable conservative idiot nor a liberal freak.
Neither an unreasonable conservative idiot nor a liberal freak.
Proof?
• Improved breast cancer subtyping vs PAM50
• Links to survival + tumor mutational burden
• Free R package + web app for the community
👉 www.karakachlab.org/software/int...
• Improved breast cancer subtyping vs PAM50
• Links to survival + tumor mutational burden
• Free R package + web app for the community
👉 www.karakachlab.org/software/int...
September 21, 2025 at 5:23 PM
Proof?
• Improved breast cancer subtyping vs PAM50
• Links to survival + tumor mutational burden
• Free R package + web app for the community
👉 www.karakachlab.org/software/int...
• Improved breast cancer subtyping vs PAM50
• Links to survival + tumor mutational burden
• Free R package + web app for the community
👉 www.karakachlab.org/software/int...
The solution: kPPA-CART
It digs into those low-signal regions, integrates transcriptomics, proteomics & methylation data, and finds real biological meaning others miss.
It digs into those low-signal regions, integrates transcriptomics, proteomics & methylation data, and finds real biological meaning others miss.
September 21, 2025 at 5:23 PM
The solution: kPPA-CART
It digs into those low-signal regions, integrates transcriptomics, proteomics & methylation data, and finds real biological meaning others miss.
It digs into those low-signal regions, integrates transcriptomics, proteomics & methylation data, and finds real biological meaning others miss.
What’s the problem? 🤔
Most computational tools in bioinformatics only detect strong, obvious signals. Subtle, low-intensity features (the ones that really matter for biology) get lost in the noise.
Most computational tools in bioinformatics only detect strong, obvious signals. Subtle, low-intensity features (the ones that really matter for biology) get lost in the noise.
September 21, 2025 at 5:22 PM
What’s the problem? 🤔
Most computational tools in bioinformatics only detect strong, obvious signals. Subtle, low-intensity features (the ones that really matter for biology) get lost in the noise.
Most computational tools in bioinformatics only detect strong, obvious signals. Subtle, low-intensity features (the ones that really matter for biology) get lost in the noise.
Like Dj Khalid, another one from the KarakachLab!
We just dropped kPPA-CART in @narjournal.bsky.social, a new machine learning method that finds hidden signals in messy multi-omics data. From kidney aging 🧬 to breast cancer 🎗️, it uncovers patterns others miss.
doi.org/10.1093/nar/...
We just dropped kPPA-CART in @narjournal.bsky.social, a new machine learning method that finds hidden signals in messy multi-omics data. From kidney aging 🧬 to breast cancer 🎗️, it uncovers patterns others miss.
doi.org/10.1093/nar/...
September 21, 2025 at 5:19 PM
Like Dj Khalid, another one from the KarakachLab!
We just dropped kPPA-CART in @narjournal.bsky.social, a new machine learning method that finds hidden signals in messy multi-omics data. From kidney aging 🧬 to breast cancer 🎗️, it uncovers patterns others miss.
doi.org/10.1093/nar/...
We just dropped kPPA-CART in @narjournal.bsky.social, a new machine learning method that finds hidden signals in messy multi-omics data. From kidney aging 🧬 to breast cancer 🎗️, it uncovers patterns others miss.
doi.org/10.1093/nar/...
Hey @dalhousieu.bsky.social, does this qualify as an own goal?
August 26, 2025 at 12:00 PM
Hey @dalhousieu.bsky.social, does this qualify as an own goal?
…lunar eclipse as seen from the karakach residence at 4:12 on pie day.
March 15, 2025 at 12:48 AM
…lunar eclipse as seen from the karakach residence at 4:12 on pie day.