karuneshganguly.bsky.social
Karunesh Ganguly MD PhD
@karuneshganguly.bsky.social
520 followers 99 following 13 posts
Neurologist, Neuroscientist & Neural Engineer - Augmenting motor function using sleep engineering, neuromodulation & BCIs. @UCSF Neurology. Posts are my opinion. gangulylab.org
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karuneshganguly.bsky.social
Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · 18h
New paper from lab: www.cell.com/neuron/fullt...
Restoration of temporal separability between beta and movement ensemble co-firing with motor recovery
Choi et al. demonstrate that stroke disrupts temporal separability between beta and movement-related ensemble co-firing states, which is restored during recovery. They also show that low-frequency alt...
www.cell.com
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Reposted by Karunesh Ganguly MD PhD
sainsburywellcome.bsky.social
Sainsbury Wellcome Centre @sainsburywellcome.bsky.social · 16d
Applications are now open for the SWC Systems Neuroscience PhD Programme.

Join us in London!

🧠 World-class neuroscience training
💰 Fully-funded 4-year programme
🖥️ Close links to @gatsbyucl.bsky.social

Apply by 3 Nov: www.sainsburywellcome.org/web/content/...
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karuneshganguly.bsky.social
Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · 20d
www.universityofcalifornia.edu/news/thrilli.... Great write up about BCI research in the UC system.
Thrilling progress in brain-computer interfaces from UC labs
UC researchers and the patients they work with are showing the world what's possible when the human mind and advanced computers meet.
www.universityofcalifornia.edu
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karuneshganguly.bsky.social
Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · Aug 8
elifesciences.org/reviewed-pre...
Separable global and local beta burst dynamics in motor cortex of primates
elifesciences.org
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Reposted by Karunesh Ganguly MD PhD
asnrehab.bsky.social
ASNR @asnrehab.bsky.social · Apr 25
Engaging presentation from Dr. @karuneshganguly.bsky.social Ganguly discussing brain-computer interface (#BCI) decoders. He shares decoding challenges and how we can use electrocorticography to create more stable, longterm control of BCI devices. 🧠🔄 🧠📈 🧪
Dr. Karunesh Ganguly presenting at #ASNR2025 Dr. Karunesh Ganguly presenting at #ASNR2025 Dr. Karunesh Ganguly presenting at #ASNR2025
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Reposted by Karunesh Ganguly MD PhD
asnrehab.bsky.social
ASNR @asnrehab.bsky.social · Mar 26
Our final Symposium at #ASNR2025 will feature presentations from Dr. Leigh Hochberg, Dr. @karuneshganguly.bsky.social, Ian Burkhart, and Dr. DJ Seo focused on understanding the end-user experience and decoding intentions for implantable brain-computer interfaces. 🧠🔄 🧠📈 🧪
www.asnr.com/i4a/pages/in...
The text at the top reads, "Join us at #ASNR2025 to learn from experts in this Symposium session!" Below to the left, the text reads, "Implantable Brain-Computer Interfaces: Understanding the End-User Experience and Decoding Intentions, Friday, April 25, 2025, 11:00 am - 12:00 pm ET, Grand Hyatt Buckhead in Atlanta, GA." The logo for the American Society of Neurorehabilitation (ASNR) is included below. On the right, there are headshot photos of the four speakers listed in the post.
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Reposted by Karunesh Ganguly MD PhD
mcuban.bsky.social
Mark Cuban @mcuban.bsky.social · Mar 22
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
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Reposted by Karunesh Ganguly MD PhD
asnrehab.bsky.social
ASNR @asnrehab.bsky.social · Mar 19
Day 3 of #ASNR2025 will feature a fantastic symposium from Drs. Jason Carmel, @karuneshganguly.bsky.social, Natasha Kharas, & Naohiko Okabe on their work focused on improving neurological function by imposing brain rhythms with electrical & magnetic stimulation. 🧠🔄 🧠📈 🧪

www.asnr.com/i4a/pages/in...
The text at the top reads, "Register for #ASNR2025 today to make sure you don’t miss this Symposium Session!". Below to the left, there are headshot photos of the four speakers mentioned in the post. The text on the right reads, "Imposing Brain Rhythms With Electrical and Magnetic Stimulation to Improve Neurological Function, Friday, April 25, 2025, 9:45 - 10:45 am ET, Grand Hyatt Buckhead in Atlanta, GA". The logo for the American Society of Neurorehabilitation appears below.
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Reposted by Karunesh Ganguly MD PhD
asnrehab.bsky.social
ASNR @asnrehab.bsky.social · Mar 17
#ASNR2025 attendees will learn more about educational approaches to the lived experience of brain injury in this symposium session! We're excited to get insights from our speakers @nettagurari.bsky.social, James Sulzer, Steven Nape, and Kevin Parcetich! 🧠🔄 🧠📈 🧪

www.asnr.com/i4a/pages/in...
The text at the top reads, "Get ready for this outstanding Scientific Symposium at #ASNR2025!". On the left, the text reads, "The Human Side of Brain Injury: Educational Approaches to the Lived Experience. Thursday, April 24, 2025, 11am - 12pm ET, Grand Hyatt Buckhead in Atlanta, GA." The logo for the American Society of Neurorehabilitation appears below. On the right, there are headshot photos of the four speakers listed in the post.
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Reposted by Karunesh Ganguly MD PhD
neuroengineering.bsky.social
Neuroengineering @neuroengineering.bsky.social · Mar 7
Researchers at UCSF showed that imagined movement patterns in the brain remain stable but can flexibly adapt to improve BCI control. This balance enabled tetraplegic participants to reliably operate a high-DOF robotic arm.

@karuneshganguly.bsky.social
www.sciencedirect.com/science/arti...
Sampling representational plasticity of simple imagined movements across days enables long-term neuroprosthetic control
The nervous system needs to balance the stability of neural representations with plasticity. It is unclear what the representational stability of simp…
www.sciencedirect.com
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karuneshganguly.bsky.social
Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · Mar 6
This allows long-term control over months. Notably, we find evidence of degradation of control over long periods. We can restore performance with a brief recalibration procedure.
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karuneshganguly.bsky.social
Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · Mar 6
We find evidence for 'representational drift', evident as changes in the centroid. Decoders that sample multiple days can account for the observed drift.
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karuneshganguly.bsky.social
Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · Mar 6
Using closed-loop training, we can improve decoder performance. This is highly context specific.
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karuneshganguly.bsky.social
Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · Mar 6
graphical abstract:
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karuneshganguly.bsky.social
Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · Mar 6
Excited to present our long-term ECoG BCI control study in two participants. Fantastic teamwork all around!

Sampling representational plasticity of simple imagined movements across days enables long-term neuroprosthetic control.

authors.elsevier.com/sd/article/S...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com
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Reposted by Karunesh Ganguly MD PhD
asnrehab.bsky.social
ASNR @asnrehab.bsky.social · Feb 27
Our next Annual Meeting is less than 2 months away! Make sure to register for the meeting by March 31st to take advantage of our reduced Early Bird Registration rates!

Visit our website for more information: www.asnr.com/i4a/pages/in...

#ASNR2025 #neurorehabilitation #rehabilitation #neuroscience
The text at the top reads, "Register by March 31st for Early Bird Rates!" Below, there is an image of the Atlanta skyline. The text reads, "2025 ASNR Annual Meeting, April 23-25, 2025 | Atlanta, Georgia". The logo for the American Society of Neurorehabilitation (ASNR) appears on the right.
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Reposted by Karunesh Ganguly MD PhD
earlkmiller.bsky.social
Earl K. Miller @earlkmiller.bsky.social · Nov 23
Huge influx of neuroscientists migrates to Bluesky
www.thetransmitter.org/community/hu...
#Neuroscience
‘Huge influx’ of neuroscientists migrates to Bluesky
Daily neuroscience-related posts on the social-media platform this week have increased more than 400 percent, on average, compared with October.
www.thetransmitter.org
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Reposted by Karunesh Ganguly MD PhD
nytimes.com
The New York Times @nytimes.com · Jan 30
Breaking News: The FDA approved a new medication to treat pain from an injury or surgery. Unlike opioid pain medicines, it cannot become addictive.
FDA Approves Journavx Drug to Treat Pain Without Addiction Risk
The drug, Journavx by Vertex Pharmaceuticals, blocks pain signals to the brain, making it nonaddictive.
www.nytimes.com
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karuneshganguly.bsky.social
Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · Jan 16
thanks; definitely a team effort
karuneshganguly.bsky.social
Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · Jan 15
We used our 'ringtrode' to change phasic excitability and reduce the reactivation rate. We found evidence of significantly lower performance gains after brief breaks.
karuneshganguly.bsky.social
Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · Jan 15
Excited to share work on how ensemble reactivations during brief rest periods drive performance gains. Marlene Bonstrup and Leonardo Cohen found evidence for 'micro-offline gains'. We find casual evidence for ensemble reactivations during brief rest periods in driving gains. rdcu.be/d6mpe
Ensemble reactivations during brief rest drive fast learning of sequences
Nature - In macaques, motor cortex activity associated with motor learning tasks is reactivated during brief breaks between learning blocks and predicts subsequent performance gains.
rdcu.be
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karuneshganguly.bsky.social
Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · Dec 27
Really enjoyed the conference a couple of years ago. Look forward to it in 2025!
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Reposted by Karunesh Ganguly MD PhD
lakeconferences.bsky.social
Lake Conferences @lakeconferences.bsky.social · Nov 22
Join us for the Sensation and Action conference 2025 – application is now open: lakeconferences.org
Home - Lake Conferences
lakeconferences.org
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karuneshganguly.bsky.social
Karunesh Ganguly MD PhD @karuneshganguly.bsky.social · Dec 15
NREM sleep improves behavioral performance by desynchronizing cortical circuits - very interesting! www.science.org/doi/10.1126/...
NREM sleep improves behavioral performance by desynchronizing cortical circuits
Sleep improves cognitive performance, yet little is known about the neural mechanisms of this improvement. We performed multielectrode recording in macaque visual and dorsolateral prefrontal cortex wh...
www.science.org
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Reposted by Karunesh Ganguly MD PhD
thomasandrillon.bsky.social
Thomas Andrillon @thomasandrillon.bsky.social · Nov 27
Amazing work from the team of Anita Lüthi!

Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep cycle
www.nature.com/articles/s41...
💤🧪🧠
Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep cycle - Nature Neuroscience
Lüthi and colleagues show that activity of the locus coeruleus (LC) is crucial for the cyclic alternation between non-rapid-eye-movement and rapid-eye-movement sleep. Stressful experiences during waki...
www.nature.com
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