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Katie Gillies @katiegillies.bsky.social · 20d

This time next year we will be wrapping up #ICTMC2026 in Birmingham. I'm already starting to think through ideas for abstracts. What trials methods research do you hope to hear about/present at the conference?

ictmc.org

ICTMC 2026 – International Clinical Trials Methodology Conference

ictmc.org

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Reposted by Katie Gillies

Jolyn Hersch PhD @jolynhersch.bsky.social · 26d

*New publication*

Interventions to support patient decision making about taking part in health research: A systematic review

doi.org/10.1016/j.pe...

Just out in Patient Education & Counseling

@sydneyhealthliteracylab.org.au @katiegillies.bsky.social

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Katie Gillies @katiegillies.bsky.social · May 21

@anniestats.bsky.social gave a great talk on decentralised trials. Main message from PhD review work is there isn't a one size fits all approach. Trial design may need to be contextually determined and responsive to population needs #SCT2025

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Katie Gillies @katiegillies.bsky.social · May 21

@liamhbishophealth.bsky.social kicks off his talk at #SCT2025 by thanking the Society for continuing to create space for raising EDI issues in clinical trials through recognition across sessions and committees. And gives a great talk on building trust through community focussed workshops and videos.

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Katie Gillies @katiegillies.bsky.social · May 21

Using imp sci to consider how actionable regulatory guidance is for diversity in clinical trials. Rebecca Metcalfe highlights that more work is needed to make system-level changes to where and how trials are conducted. Building trusted relationships & enforcing guidance are key next steps #SCT2025

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Katie Gillies @katiegillies.bsky.social · May 20

Well done on your poster prize Kara!

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Katie Gillies @katiegillies.bsky.social · May 20

If you want more trials methods research post #SCT2025 please do come to #ICTMC2026 in Birmingham UK 14-17 September. More here ictmc.org

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Katie Gillies @katiegillies.bsky.social · May 20

Adwoa Parker walking us through the update of the Cochrane review on interventions to improve recruitment. 7 years & >50 new studies doesn't tell us much more with high certainty. Suggests trialists think carefully about using interventions with no effect (bottom 3 in pic) #SCT2025

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Katie Gillies @katiegillies.bsky.social · May 20

Founders Lecture #SCT2025 on DMCs - Thomas Fleming flags the @nihr.bsky.social funded DAMOCLES study that developed a charter for DMCs to support them to do their jobs well. Full paper here www.thelancet.com/journals/lan...

A proposed charter for clinical trial data monitoring committees: helping them to do their job well

Formal monitoring of data from randomised controlled trials (RCTs) is becoming more common. Wide variation exists in the structure and organisation of data monitoring committees (DMCs), with little gu...

www.thelancet.com

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Reposted by Katie Gillies

MRC-NIHR Trials Methodology Research Partnership @mrcnihrtmrp.bsky.social · May 20

See how we can enable lower carbon clinical trials without compromising health outcomes. UCD, University of Liverpool, University of Galway, ICR, the HRB-TMRN, MRC-NIHR TMRP & PPI partners, co-developed this video about Greener Trials. www.youtube.com/watch?v=LbgG... #internationalclinicaltrialsday

Greener Trials

YouTube video by UCD Medicine

www.youtube.com

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Reposted by Katie Gillies

UK CTU Network @ukcrc-ctu.org.uk · May 20

From development to delivery, it takes a collaborative multidisciplinary team to make a clinical trial successful.

Find out more about how Clinical Trials Units make research happen here: ukcrc-ctu.org.uk

#ICTD2025 #ClinicalTrials #CTD2025

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Reposted by Katie Gillies

Aberdeen Centre for Evaluation (formerly HSRU) @ace-aberdeen.bsky.social · May 20

#ClinicalTrialsDay is the time to consider how to ensure the environmental sustainability of clinical trials. Read our @frankskyou.bsky.social write about why and how greener trials serve the purpose of benefiting the coming generations on SpringerNature blog: bit.ly/4moCL11

Towards Greener Trials

In celebration of International Clinical Trials Day, which this year has a sub-theme around ‘benefiting generations to come’, Frank Sui-keung You from the University of Aberdeen explains why our plane...

communities.springernature.com

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Katie Gillies @katiegillies.bsky.social · May 19

My highlight from #SCT2025 day 1 was Mollie Paynes talk on her PhD research on dose-response methodology in complex intervention trials. It's always great to hear a statistics talk that non-statisticians can also follow. Perfectly pitched. More on Mollies work here github.com/molliejpayne...

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Reposted by Katie Gillies

UK CTU Network @ukcrc-ctu.org.uk · May 19

Tomorrow isn’t just International Clinical Trials Day.

Keep your eyes peeled for the launch of our strategy for 2025 – 2030!

#UKCTUNetwork #CTUNetworkStrategy

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Katie Gillies @katiegillies.bsky.social · May 19

Late breaking session at #SCT2025 on the impact of recent US govt actions. So important for us to come together as a trials community to collectively support the research endeavour and our US colleagues. Flags an opinion piece in @nytimes.com today that encourages us to 'get mad in public'

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Katie Gillies @katiegillies.bsky.social · May 19

There is a need for trials methodology research for trials designed & delivered in the global south. Sangeetha Paramasivan flags article on need for this work in RCTs in India & talks through adaptation of quintet recruitment intervention in this setting #SCT2025 www.thelancet.com/journals/lan...

Trials Methodology Research: what is it and why should India invest in it?

This Viewpoint presents an overview of trials methodology research (TMR) and the case for investing in TMR in India. Randomised controlled trials and other types of clinical research inform evidence-b...

www.thelancet.com

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Katie Gillies @katiegillies.bsky.social · May 19

Arun Sanyal giving the Curtis Meinert Keynote @ #SCT2025 talks us through the use of Desirability of Outcome Ranking (DOOR) in liver trials. Makes a suggestion for pan-specialty #CoreOutcomeSets to facilitate DOOR integration in evidence synthesis for intersecting clinical contexts.

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Katie Gillies @katiegillies.bsky.social · Apr 15

One of our PhD students, Mojca Cerar, is running a survey to understand how recruitment & retention data in trials is communicated with trial sites. If you have any role in this process please complete our 10 min survey. We only have 23 responses with 2 weeks to go! forms.office.com/e/9RCxiiCXM2

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Reposted by Katie Gillies

Gary Collins @gscollins.bsky.social · Apr 15

NEW PAPER: Updated CONSORT-2025 for reporting randomised trials is now available in the @bmj.com @jama.com , @thelancet.bsky.social, @plos.org and @naturemedicine.bsky.social

—> www.bmj.com/content/389/...

#openscience #transparency #medsky #statssky #episky

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Reposted by Katie Gillies

Kerry Hood @kerryhood.bsky.social · Apr 15

Improving how we approach informing people about the potential risks and benefits of trial interventions.

trialsjournal.biomedcentral.com/articles/10....

Variation in the extent to which patient information leaflets describe potential benefits and harms of trial interventions: a commentary - Trials

Clinical trial participants must understand the possible risks and benefits of trial interventions before providing their informed consent to participate. The aim of this commentary is twofold: to sum...

trialsjournal.biomedcentral.com

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Reposted by Katie Gillies

Shaun Treweek @streweek.bsky.social · Feb 14

If you are doing work on equity, diversity and inclusion in randomised controlled trials, the journal Trials has a special series you could submit to:

www.biomedcentral.com/collections/...

Deadline end of June, and articles can be original research, commentary, education but not protocols.

Screenshot of part of the series description available at the link.

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Reposted by Katie Gillies

Jolyn Hersch PhD @jolynhersch.bsky.social · Feb 20

Trial participant self‑reported understanding of randomisation phrases in participant info can be high but acceptability of some descriptions is low esp if linked to gambling/luck
@streweek.bsky.social @katiegillies.bsky.social @taliaisaacs.bsky.social
trialsjournal.biomedcentral.com/articles/10....

Trial participants’ self-reported understanding of randomisation phrases in participation information leaflets can be high, but acceptability of some descriptions is low, especially those linked to ga...

Background Evidence indicates that trial participants often struggle to understand participant information leaflets (PILs) for clinical trials, including the concept of randomisation. We analysed the ...

trialsjournal.biomedcentral.com

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Katie Gillies @katiegillies.bsky.social · Feb 12

Currently low response rates from CTU Directors (n=5), Programmers/Data Managers (n=0), & QA Managers (n=3) working in clinical trials. We need to know what these groups think the challenges are for greener trials.

forms.office.com/e/fkeLD8HbMA

Please complete &RT

@ukctunetwork.bsky.social

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Katie Gillies @katiegillies.bsky.social · Feb 5

We now have 71 responses but need more if we are to identify the key challenges for the design and delivery of greener trials.

Please complete and share onwards. Average completion time is only 12mins. We need to hear from you.

forms.office.com/e/fkeLD8HbMA

Thank you

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Katie Gillies @katiegillies.bsky.social · Feb 5

Thanks Jenny. @oxprimarycare.bsky.social it would be great if those of you working on trials could complete and share this link forms.office.com/e/fkeLD8HbMA

Thank you

Microsoft Forms

forms.office.com

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