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Reposted by Shaun Treweek

Aberdeen Centre for Evaluation (formerly HSRU) @ace-aberdeen.bsky.social · 23d

📣 Our @streweek.bsky.social is lead author on an editorial in #Trials outlining a new mandate in the journal - mandating the reporting of six key participant characteristics in any protocol/trial report submitted to Trials on or after 1st Jan 2026. 1/2
trialsjournal.biomedcentral.com/articles/10....

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Shaun Treweek @streweek.bsky.social · 26d

I'm unsure. But evaluating what we do seems sensible. And perhaps we should bundle things a bit more in SWATs so that we evaluate a broader strategy rather than a single component of strategy, sometimes at least.

Shaun Treweek @streweek.bsky.social · 26d

From 1st Jan 2026, the journal Trials will mandate reporting of (at least) six participant characteristics for both protocols and reports of trial results. Read more in the editorial:

trialsjournal.biomedcentral.com/articles/10....

@ukcrc-ctu.org.uk @ecrin.bsky.social

Who is in your trial? Improving the reporting of participant characteristics in trial protocols and results - Trials

trialsjournal.biomedcentral.com

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Shaun Treweek @streweek.bsky.social · Jun 20

It's Red4Research Day today!

Thanks to everyone – research participants, patients, professionals, volunteers and regulatory bodies – working together to do health and social care research.

rdforum.nhs.uk/red4research...

#Red4Research

Picture of Shaun thanking people supporting health and care research in 2025 as part of Red4Research Day 2025.

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Shaun Treweek @streweek.bsky.social · Jun 19

A couple of Studies Within A Trial (SWATs), one results, one a protocol, just out in the journal Trials:

trialsjournal.biomedcentral.com/articles/10....

trialsjournal.biomedcentral.com/articles/10....

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Reposted by Shaun Treweek

The People's Review @thepeoplesreview.ie · May 20

🎉 Stage 2 is LIVE - where YOU get to decide the People's favourite question!

➡️ If you're joining The People's Review for the first time sign-up here: buff.ly/kAuYITA

➡️ If joined us for Stage 1 you can login in directly to Cochrane Crowd here: buff.ly/q0WudTM

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Shaun Treweek @streweek.bsky.social · May 8

The Edinburgh Clinical Trial Management Course, Nov 6th and 7th 2025 in Edinburgh, is now open for bookings:

clinical-research-facility.ed.ac.uk/edinburgh-cl...

The Edinburgh Clinical Trial Management Course flyer, the details on it are available at the link in the post.

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Shaun Treweek @streweek.bsky.social · May 6

We’re bombarded with health advice 24/7. Systematic reviews help cut through the noise—but most people don’t know what they are.

💥 That’s where #ThePeoplesReview comes in. Learn about systematic reviews, by doing a systematic review

🔗https://www.thepeoplesreview.ie/join-now

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Reposted by Shaun Treweek

SENSITISE (Inclusive clinical trials education) @sensitise-eu.bsky.social · May 5

To kick off #MethodologyMonday in May, we bring you a poignant article by the Editors in Chief of the Journal of Clinical Epidemiology. They address the “elephant in the room”, the upheaval of the global evidence research eco-systems pursued by the US administration.
www.jclinepi.com/article/S089...

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Reposted by Shaun Treweek

dysphagia matters @dysphagiamatters.bsky.social · Apr 28

We spoke with @streweek.bsky.social about why so much health research still falls short. Shaun argues that big parts of health research is “bad” & does not bring the needed value to the evidence-base. Tune in to learn how we can conduct “good” research for our patients 🎙️!

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Reposted by Shaun Treweek

MRC Clinical Trials Unit at UCL @mrcctu.bsky.social · May 5

💻 Come along to our next Capacity Strengthening Hub webinar with @tghn-news.bsky.social to hear about experts' experience, general principles and a practical framework for communicating #ClinicalTrials results with participants.

🗓️ 2 June
🕙 10:00-11:30 BST
📍 Online

Register now: bit.ly/4k28ALd

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Shaun Treweek @streweek.bsky.social · Apr 22

We’re bombarded with health advice 24/7. 😵‍💫 Systematic reviews help cut through the noise—but most people don’t know what they are.

💥 That’s where #ThePeoplesReview comes in. Learn about systematic reviews, by doing a systematic review

www.thepeoplesreview.ie

A picture of the webpage that you get to at the link. It shows lots of different types of people.

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Reposted by Shaun Treweek

SENSITISE (Inclusive clinical trials education) @sensitise-eu.bsky.social · Apr 21

This literature review identified strategies to enhance the racial & ethnic diversity of breast cancer trial populations. It resulted in 8 key strategic themes, which were used to create a new Racial and Minority Growth model.
#MethodologyMonday
Scott & Westwell
orca.cardiff.ac.uk/id/eprint/17...

orca.cardiff.ac.uk

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Reposted by Shaun Treweek

Marion Campbell @marionkcampbell.bsky.social · Apr 21

A major update to the CONSORT reporting guidance for clinical trials was published last week.
📌 CONSORT 2025 replaces all previous versions and should be used from now on.
So what’s new and what’s different? 1/7
#MethodologyMonday #116
(COI - I am a co-author)

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Reposted by Shaun Treweek

The People's Review @thepeoplesreview.ie · Apr 14

🚨We are thrilled that our protocol has been selected as the article of the month in Research Involvement and Engagement.

Full article here: researchinvolvement.biomedcentral.com/articles/10....

#ThePeoplesReview #PoweredByThePublic #ArticleOfTheMonth

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Reposted by Shaun Treweek

trialforge.bsky.social @trialforge.bsky.social · Apr 11

We have just created a library of participant information leaflets for trials, over 200, if you are looking for inspiration.

Check out:

www.trialforge.org/excelsior-pi...

The is part of EXCELSIOR, a project ed by Frances Shiely at Cork University.

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Shaun Treweek @streweek.bsky.social · Apr 3

Many thanks! I hope that you are well, and having the same lovely weather that we are.

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Shaun Treweek @streweek.bsky.social · Apr 2

Today has been lovely, a grant was funded, had a couple of very productive and enjoyable meetings, got some stuff off my To Do list and the sun is shining. If a red squirrel came to the bird feeder at tea-time, that really would be the cherry on the top.

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Reposted by Shaun Treweek

Darren Dahly @statsepi.bsky.social · Mar 31

Many thanks to @vcornelius.bsky.social and @gsmaclennan.bsky.social for coming to Cork and sharing their wisdom on clinical trials today.

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Reposted by Shaun Treweek

Aberdeen Centre for Evaluation (formerly HSRU) @ace-aberdeen.bsky.social · Mar 25

Interested in audit and feeback strategies and how they may improve healthcare practice? Then check out the updated Cochrane review on the topic, co-authored by our own Kristin Konnyu:

Audit and feedback: effects on professional practice - Ivers, N - 2025 www.cochranelibrary.com/cdsr/doi/10....

Audit and feedback: effects on professional practice - Ivers, N - 2025 | Cochrane Library

Select your preferred language for Cochrane reviews and other content. Sections without translation will be in English.

www.cochranelibrary.com

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Reposted by Shaun Treweek

Aberdeen Centre for Evaluation (formerly HSRU) @ace-aberdeen.bsky.social · Mar 31

🆕Paper📢
In their follow-up study in ‘Tolerating bad health research’, Shaun Treweek and colleagues conducted risk of bias assessment of 140 UK, Irish and Canadian trials. Despite the bad trials (55%), trials judged to be good increased from 9% to 16%.
trialsjournal.biomedcentral.com/articles/10....

Tolerating bad health research (part 2): still as many bad trials, but more good ones too - Trials

Background We previously published a study examining the risk of bias of a random selection of Cochrane systematic reviews. The purpose of our current study is to reassess the risk of bias of a cohort...

trialsjournal.biomedcentral.com

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Shaun Treweek @streweek.bsky.social · Mar 31

Tolerating bad health research (part 2):

trialsjournal.biomedcentral.com/articles/10....

In summary, after risk of bias reassessment of 140 UK, Irish and Canadian trials, there were still as many bad trials (55%) but trials judged to be good increased from 9% to 16%.

Not very reassuring really.

Tolerating bad health research (part 2): still as many bad trials, but more good ones too - Trials

Background We previously published a study examining the risk of bias of a random selection of Cochrane systematic reviews. The purpose of our current study is to reassess the risk of bias of a cohort...

trialsjournal.biomedcentral.com

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Reposted by Shaun Treweek

Gareth Hollands @gjhollands.bsky.social · Mar 28

❗ Latest issue of @thelancet.bsky.social out today and featuring the TEMPO trial on the cover 🙂

My summary thread here: bsky.app/profile/gjho...
Open access paper here:
www.thelancet.com/journals/lan...

The Lancet @thelancet.com · Mar 28

Understanding colorectal cancer screening behaviour is key to increasing uptake.

In our latest issue, a recent trial evaluates the impact of two behavioural interventions on uptake of FIT colorectal screening.

Find this & more 👉 tinyurl.com/y9sjj4hc

Cover of the March 29, 2025 issue of The Lancet. Quote on cover reads: “Our findings show the potential for low-cost or no-cost behavioural interventions to increase participation in screening and reduce deaths from colorectal cancer [by] adding one sentence to the invitation letter.”

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Shaun Treweek @streweek.bsky.social · Mar 27

Here's a new risk of bias tool for systematic reviews: ROBUST-RCT

www.bmj.com/content/388/...

Similar to an older Cochrane risk of bias tool, it looks like something that could actually be used, which is great. The team explicitly aimed to balance simplicity and methodological rigour.

The 6 core items of the new risk of bias tool. Also in paper at the link.

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Reposted by Shaun Treweek

trialforge.bsky.social @trialforge.bsky.social · Mar 27

Here's an interesting rapid review on strategies to enhance the ethnic diversity of breast cancer clinical drug trials. It gives some trial recruitment and retention recommendations too.

www.academia.edu/2998-7741/1/...

Figure 3 from the paper, which gives the eight themes identified in the review.

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