Lightnews — Scholar-powered news

Reposted by Kristina Micheva

Andrew Payne @andrewcpayne.bsky.social · 7d

E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.

Read more: e11.bio/blog/prism

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Kristina Micheva @kdmicheva.bsky.social · 10d

Back from a trip and I found this unintentional present I left myself

A sprouted sweet potato puts a gorgeous display of delicate pinkish-purpelish stems and leaves

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Kristina Micheva @kdmicheva.bsky.social · Aug 15

We should definitely think and talk more about this! Ignoring these blind spots can be damaging to both our science and our morality. Some of us try to appease our conscience by sparing other animal lives - gently taking spiders outside, becoming vegetarian, but that does not resolve the conflict

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Reposted by Kristina Micheva

Davi Bock @dddavi.bsky.social · Aug 14

It was a good experience to step back and briefly take stock of the amazing progress in connectomics since I started working on this stuff (20 years ago!)

thanks as well to @natrevneuro.nature.com for the constructive editorial interactions.

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Kristina Micheva @kdmicheva.bsky.social · Aug 12

Ultramicrotomy escapism: trimming blocks and enjoying the shapes and colors 💕

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Kristina Micheva @kdmicheva.bsky.social · Aug 6

🤣

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Kristina Micheva @kdmicheva.bsky.social · Aug 1

Our 2nd Array Tomography Workshop will be in November in Buenos Aires and there is still time to apply! Five days of hands-on learning, discussions and talks + gorgeous electron microscopy and immunofluorescence. Focus on simple and affordable workflows.
www.arraytomography.org/workshop-202...

Workshop 2025

About the workshop This workshop will cover array tomography (AT) technology with a focus on “simple and affordable” workflows based on serial ultramicrotomy and imaging. The practicals include...

www.arraytomography.org

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Reposted by Kristina Micheva

Marine Biological Laboratory @mblscience.bsky.social · Jul 28

We're thrilled to announce the largest private gift in our 137-year history: a $25 million unrestricted donation from MBL Whitman Scientist Mark Terasaki.

His extraordinary generosity will bolster our renowned research and education programs. 🔬

Learn more: bit.ly/452WL1m

MBL Announces Largest Ever Gift for Its Renowned Biological Education and Research Programs | Marine Biological Laboratory

Cell Biology Researcher Mark Terasaki’s $25 Million Unrestricted Gift Will Support Operations and Infrastructure Contact: Samantha Cummis [email protected]; 973.800.4119

bit.ly

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Kristina Micheva @kdmicheva.bsky.social · Jul 14

Congratulations!

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Reposted by Kristina Micheva

Jemima Burden @jemimaburden.bsky.social · Jul 3

Excited to announce registration to the next Array Tomography workshop in Buenos Aires is now open!

#volumeEM

See our AT website page for more information ⬇
www.arraytomography.org/workshop-202...

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Kristina Micheva @kdmicheva.bsky.social · Jun 26

Looks like autofluorescence to me (not an olfactory expert). Could it be lipofuscin, I see that a lot in cortex where I mostly look? A quick search of lipofuscin and olfactory bulb brought this paper and the images look pretty similar to yours: pubmed.ncbi.nlm.nih.gov/19666062/

Distinct domanial and lamellar distribution of clustered lipofuscin granules in microglia in the main olfactory bulb of young mice - PubMed

Lipofuscin granules are generally considered as age-pigment. However, we encountered numerous large irregular clusters of lipofuscin granules in the olfactory nerve layer and glomerular layer of the m...

pubmed.ncbi.nlm.nih.gov

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Kristina Micheva @kdmicheva.bsky.social · Jun 19

Congratulations! You are amazing!

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Kristina Micheva @kdmicheva.bsky.social · Jun 5

Congratulations!

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Reposted by Kristina Micheva

lyons-lab.bsky.social @lyons-lab.bsky.social · May 14

For those who want a distraction and/ or are interested, here's the latest from the group, led by Phil Braaker

www.nature.com/articles/s41...

Activity-driven myelin sheath growth is mediated by mGluR5 - Nature Neuroscience

Employing pharmacology, genetics and all-optical approaches in zebrafish, Braaker et al. find that neuronal activity influences the growth of myelin sheaths along axons by signaling through metabotrop...

www.nature.com

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Kristina Micheva @kdmicheva.bsky.social · Apr 1

I'm so sorry, there's no words

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Kristina Micheva @kdmicheva.bsky.social · Mar 13

Congratulations! Looking forward to all the exciting work to come from this!

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Kristina Micheva @kdmicheva.bsky.social · Feb 27

+1

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Reposted by Kristina Micheva

Christophe 🔬 L @christlet.bsky.social · Jan 31

Reminder that @europepmc.org is a mirror of Pubmed with better search and that it indexes *all* bioRxiv preprints (as well as ResearchSquare), not just the ones funded by NIH like chauvinist Pubmed

Prasad Jallepalli, MD, PhD @prasad.bsky.social · Jan 31

I’m very scared to see what happens to PubMed

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Kristina Micheva @kdmicheva.bsky.social · Jan 30

Congratulations! Can't wait to read it!

Reposted by Kristina Micheva

Kevin Mitchell @wiringthebrain.bsky.social · Jan 20

What happened to the pursuit of truth? rupress.org/jgp/article/... - Eve Marder, on point...

What happened to the pursuit of truth? | Journal of General Physiology | Rockefeller University Press

The knowledge in our brains, not in our phones, is necessary for creative thinking and the pursuit of truth.

rupress.org

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Kristina Micheva @kdmicheva.bsky.social · Dec 26

Delighted!!! Thank you!

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Kristina Micheva @kdmicheva.bsky.social · Dec 23

Looks like a perfect winter treat, but not naming it to keep the suspense going 😂

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Kristina Micheva @kdmicheva.bsky.social · Dec 18

And welcome to @owen-lab.bsky.social who is new here!

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Kristina Micheva @kdmicheva.bsky.social · Dec 18

Happy to share a new biorxiv manuscript with @owen-lab.bsky.social where we “slice and dice” synapses with array tomography and find subclasses with different glutamate receptor composition 🧪

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · Dec 14

Data-driven synapse classification reveals a logic of glutamate receptor composition https://www.biorxiv.org/content/10.1101/2024.12.11.628056v1

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Reposted by Kristina Micheva

Hanieh Falahati @haniehfalahati.bsky.social · Dec 2

Our paper is out just in time for #EM_Monday! It is about a specialized neuron-specific ER, called the spine apparatus, which is found close to synapses and has a very peculiar shape. If you think neurons are special, the spine apparatus is their🦄 horn! But how does it form?!
doi.org/10.1016/j.cu...

Gif showing a spine containing spine apparatus, reconstructed from FIB-SEM images. ER: red, synapse: yellow, plasma membrane: blue

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