Second this.
We need more people saying this:

It’s not just US science and cancer cures at risk, it’s the whole US university system top to bottom.

CEU and Orban are their model. CEU is now gone from Hungary. And the response needed is public pushback, not quiet go-along-to-get-along.

Congrats!! Was fun to hear about this at SfN!

ha! yeah the late breaking posters are a trek 😩

Thanks, Arkarup! sorry you’re not able to be here—I’m hoping to make it to your labs’ posters!

Thanks!!

cool -- looks interesting! thanks!

we don't! but i think it's a great question and hope to do this experiment in the future

Just channeling Stephen J Gould: "I am, somehow, less interested in the weight and convolutions of Einstein's brain than in the near certainty that people of equal talent have lived and died in cotton fields and sweatshops"

thanks for reading! we only looked at lab-raised populations, but there's a rich natural history literature about climbing in wild deer mice, and wild forest mice are better climbers. hand dexterity is less well studied. urban vs populated, we don't know! but an interesting ? for sure!

same, tbh!

...probably i have too many thoughts for this format! but it's not entirely obvious to me how an increase here relates to expectations from primate evo - other than that RFA CSNs in rodents project to deeper spinal cord lamina than CFA CSNs, so perhaps more CSNs w/ fewer synapses to motor neurons

cingulate cortex (as labeled by the allen) is medial/ventral to M2/RFA, and i haven't looked at the extent to which the pattern within the rostral ctx differs - but i could, and may better answer your ?. my understanding is that RFA is often thought of as a homologue of primate SMA/premotor ctx...

we looked at all of cortex, but only neurons that project to C5-C7ish (b/c we labeled by retrograde AAV inj). we see more CSNs in what the allen atlas labels as M2 and S2, but not M1/S1. here's max intensity proj across cortex of labeled neurons -- just to clarify what i mean w/ area labels...

there are more CSNs in RFA specifically! (we’re calling RFA m2 here). I don’t have a definitive answer on other spinal proj neurons (but preliminarily, i don’t think there’s a decrease). def very open to any feedback you have after reading!

Thank you!!

...which means that they don't completely diverge. but it's complicated. you could get a genetic change that stops them from mating with one another. natural selection is not entirely predictable.

thank you! the question of "what is a species?" in these kinds of closely related populations is a bit hard to answer. but one thing we know is that there is some crossover between these populations in the wild, causing "gene flow", i.e., sharing of genetic info, between populations...