Thanks to the 320 attendees from 30 countries who joined us over two webinar sessions that explored model-specific refinements and practical tools to minimise laboratory animal suffering. If you missed the session the recording is now available.

👉 nc3rs.org.uk/3rs-resource...

New publication: Home-cage monitoring to refine and reduce animal use in drug safety testing

A cross-sector collaboration demonstrates that non-invasive, continuous monitoring of rodent behaviour improves detection of central nervous system side effects for new drugs.
👉 nc3rs.org.uk/news/home-ca...

Very intelligent animals with a great capacity for learning when given the opportunity, really looking forward to this one.

In our two-part @nc3rs.bsky.social Welfare Webinar: Minimising animal suffering through refined humane endpoints and early interventions experts shared refinements to pain models, snakebite envenoming, bone marrow ablation & more. 250+ watched live & recordings for both sessions are coming soon.

New report from the NC3Rs, in collaboration with @abpi.bsky.social and MHRA, explores how New Approach Methodologies (NAMs) can transform the way new medicines are developed, harnessing cutting edge human relevant technologies and reducing reliance on animal testing.
nc3rs.org.uk/news/incorpo...

The next webinar in our welfare series will focus on refined humane endpoints and early interventions. Join us next month, across two lunchtime sessions, with expert speakers from academia and industry.

📅 Part 1: Thursday 11 September.
📅 Part 2: Tuesday 16 September.

👉 nc3rs.org.uk/welfare-webi...

Are you looking for something to help you teach experimental design? Also at a @ukrepro.bsky.social Open Research partner institution (www.ukrn.org/partner-inst...)? Join us and learn how to the EDA can help!

A recent study showed more than half of publications using animal models of neurological disorders involved pseudoreplication (doi.org/10.1186/s132...). Avoid pseudoreplication - use the EDA to help you identify your experimental unit accurately: eda.nc3rs.org.uk/experimental...

We developed a simple mouse glucose tolerance test protocol for diabetes research with voluntary oral glucose dosing instead of gavage. More physiological/aligned to the human test & better for animal welfare 👇🏻
www.biorxiv.org/content/10.1...

Please DM for detailed info or to arrange a chat

It was great to find our mouse handling posters on some of the stands and we were very impressed to discover that the Explanation and Elaboration resource for the ARRIVE guidelines 2.0 has been translated and republished in Chinese: www.slarc.org.cn/dwyx/article...

We presented on evaluating environmental enrichment, our resources to help improve animal welfare and the role of animal technicians in helping to produce reliable results: nc3rs.org.uk/3rs-resource...

Last week, Esther Pearl and Nathalie Percie du Sert travelled to Hong Kong for the Hong Kong Laboratory Animal Sciences Society (HKLASS) symposium hklass.org. HKLASS is relatively new and it was amazing to see so much enthusiasm for the 3Rs.

We have been collaborating with HESI to advance the 3Rs in endocrine disruptor assessment since 2020. Other ongoing projects include optimising concentration setting and improving the design and data interpretation of in vivo tests using historical data.

💡Find out more: nc3rs.org.uk/3rs-resource...

We met over 100 people at our @pintofscience.uk events in Exeter, Edinburgh and London last week to explore 3Rs advances across scientific disciplines, from technology and engineering to ecology and biomedical modelling. Thanks to our speakers, the Pint of Science teams and everyone who joined us!

In our 20th issue of Tech3Rs we look back over 20 years of working with technical staff to deliver 3Rs advances in animal facilities. We re-visit two previous Tech3Rs champions, cover support to share your 3Rs work, alongside 3Rs papers of interest and webinars: nc3rs.org.uk/3rs-resource...

It's 3Rs Prize day 🎉 - join us from 14:00 BST to hear about outstanding original work that could be used for the replacement, reduction or refinement of the use of animals in research
#3RsPrize #3Rs

Read our new briefing paper, showcasing how the next generation of preclinical in vitro models can replace animal use, better recapitulate human physiology and disease and increase the efficiency of drug development: nc3rs.org.uk/news/briefin...