King Lab
@kinglabipd.bsky.social
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News from the King Lab kinglab.ipd.uw.edu.
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King Lab
@kinglabipd.bsky.social
· Aug 22
From sequence to scaffold: computational design of protein nanoparticle vaccines from AlphaFold2-predicted building blocks
Self-assembling protein nanoparticles are being increasingly utilized in the design of next-generation vaccines due to their ability to induce antibody responses of superior magnitude, breadth, and du...
www.biorxiv.org
King Lab
@kinglabipd.bsky.social
· Aug 4
Stabilization of H5 highly pathogenic avian influenza hemagglutinin improves vaccine-elicited neutralizing antibody responses
Transmission of highly pathogenic avian influenza from H5 clade 2.3.4.4b has expanded in recent years to infect large populations of birds and mammals, heightening the risk of a human pandemic. Influe...
bit.ly
King Lab
@kinglabipd.bsky.social
· Aug 1
Creating multi-protein systems with atomic precision – Institute for Protein Design
Protein design is expanding from building single molecules to generating entire systems from scratch with parts that work together in ways nature never explored.
www.ipd.uw.edu
King Lab
@kinglabipd.bsky.social
· Jun 27
Elicitation of liver-stage immunity by nanoparticle immunogens displaying P. falciparum CSP-derived antigens - npj Vaccines
npj Vaccines - Elicitation of liver-stage immunity by nanoparticle immunogens displaying P. falciparum CSP-derived antigens
www.nature.com
Reposted by King Lab
Veesler lab
@veeslerlab.bsky.social
· May 14
Phylogeny-driven design of broadly protective sarbecovirus receptor-binding domain nanoparticle vaccines
Vaccines against emerging SARS-CoV-2 variants and sarbecoviruses with pandemic potential must elicit a robust humoral immune response in a population imprinted with the SARS-CoV-2 spike (S) protein. H...
www.biorxiv.org