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Thrilled to announce my official promotion to associate professor with tenure at UTSW! So grateful to all the trainees in the lab for their hard work and proud of their accomplishments over the last several years. This an individual recognition but truly a team effort!

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Jonathan Friedman @labfriedman.bsky.social · Aug 14

thanks!

Jonathan Friedman @labfriedman.bsky.social · Aug 13

Does anyone have a favorite mNeonGreen antibody that works well for western and IPs?

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Reposted by Jonathan Friedman

Natalie Niemi @nieminm.bsky.social · May 29

Finally, we find that presequence strength influences yeast metabolism in a model of COX4 deletion. When fused to a leaderless COX4, only presequences that promote “strong” import behavior restore respiratory growth to wild-type levels. 8/n

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Reposted by Jonathan Friedman

Natalie Niemi @nieminm.bsky.social · May 29

Very excited to share our latest work, “Mitochondrial presequences harbor variable strengths to maintain organellar function,” led by the fantastically talented @washubbsb.bsky.social graduate student Youmian Yan. A 🧵

www.biorxiv.org/content/10.1...

Mitochondrial presequences harbor variable strengths to maintain organellar function

Hundreds of mitochondrial-destined proteins rely on N-terminal presequences for organellar targeting and import. While generally described as positively charged amphipathic helices, presequences lack ...

www.biorxiv.org

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Jonathan Friedman @labfriedman.bsky.social · May 23

Congrats!

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Jonathan Friedman @labfriedman.bsky.social · Apr 21

Congrats Sam!

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Reposted by Jonathan Friedman

Natalie Niemi @nieminm.bsky.social · Apr 14

Niemi lab and @washubbsb.bsky.social graduate student Youmian Yan gave a fantastic presentation on her work at the @asbmb.bsky.social meeting in Chicago! #ProudPI (photo credit to @kerikozul.bsky.social)

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Reposted by Jonathan Friedman

Michael Lazarou @lazaroulab.bsky.social · Apr 2

This is a very sad day. Shock, despair, disappointment, disbelief... These only scratch the surface in describing this decision and how I feel. I began my career in Parkinson's research in Richard's lab. What happens now to all the trainees still there?

WIRED @wired.com · Apr 2

NEW: The doctor behind breakthrough Parkinson’s research was among the scientists purged from the National Institutes of Health, the US’s leading medical research agency. www.wired.com/story/doctor...

Doctor Behind Award-Winning Parkinson’s Research Among Scientists Purged From NIH

Leading scientists at the National Institutes of Health, the US’s leading medical research agency, were swept up Tuesday in the Trump administration's latest firing blitz.

www.wired.com

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Reposted by Jonathan Friedman

Natalie Niemi @nieminm.bsky.social · Mar 28

Come to St. Louis this summer for the United Mitochondrial Disease Foundation MitoMed 2025 Conference! We have a fantastic line up with lots of opportunities for short talks. We're also running a Masterclass for Early Career Investigators. More info here: www.umdfconference.org

UMDF Conference

www.umdfconference.org

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Jonathan Friedman @labfriedman.bsky.social · Mar 25

Reminder to join us tomorrow at 12pm ET!

Jonathan Friedman @labfriedman.bsky.social · Mar 14

Join us March 26th at 12pm ET - @asbmb.bsky.social LRD seminar series.

We have two great mitochondria-focused lipid talks planned from @jasoncasler.bsky.social from @lllackner.bsky.social's lab and Kailash Venkatraman from @ibudin.bsky.social's lab.

Register here! www.asbmb.org/meetings-eve...

Lipid Research Division Seminar Series

March 26, 2025 | 12 p.m. Eastern

www.asbmb.org

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Jonathan Friedman @labfriedman.bsky.social · Mar 14

Join us March 26th at 12pm ET - @asbmb.bsky.social LRD seminar series.

We have two great mitochondria-focused lipid talks planned from @jasoncasler.bsky.social from @lllackner.bsky.social's lab and Kailash Venkatraman from @ibudin.bsky.social's lab.

Register here! www.asbmb.org/meetings-eve...

Lipid Research Division Seminar Series

March 26, 2025 | 12 p.m. Eastern

www.asbmb.org

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Jonathan Friedman @labfriedman.bsky.social · Feb 21

Awesome news! Congrats!

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Jonathan Friedman @labfriedman.bsky.social · Feb 19

Some good news (and fresh science) to break things up! Our work identifying a subpopulation of compositionally unique mitochondria that localize to filopodia and promote cell migration is now @currentbiology.bsky.social! Led by fantastic @madeleinempavey.bsky.social!

www.cell.com/current-biol...

Compositionally unique mitochondria in filopodia support cellular migration

Marlar-Pavey et al. determine that a subpopulation of compositionally unique mitochondria, METEORs, dynamically localize to filopodia. Loss of mitochondrial targeting to filopodia correlates with a re...

www.cell.com

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Jonathan Friedman @labfriedman.bsky.social · Feb 19

An excellent opportunity!

Jeremy Baskin @jeremybaskin.bsky.social · Feb 19

Some good news: applications are open for the Weill Institute Emerging Scholars Symposium @ Cornell! Senior PhD students and, now, postdocs interested in networking & presenting their work in cell & molecular biology at Cornell should apply by Apr 14. Please repost! wicmb.cornell.edu/emerging-sch...

Flyer for Weill Institute Emerging Scholars Symposium at Cornell University, with QR code at bottom to obtain more information

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Reposted by Jonathan Friedman

luskinglab.bsky.social @luskinglab.bsky.social · Feb 7

It’s so nice to be able to celebrate something this week. Newest work from the group! How are nuclear contents delivered to the cytosolic autophagy machinery while maintaining nuclear integrity? Nuclear envelope gymnastics! Cool role for Dnm1/Drp1. www.nature.com/articles/s41...

A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope - Nature Cell Biology

Mannino et al. provide a quantitative and ultrastructural timeline of nucleophagy in yeast with lattice light sheet microscopy and correlative light and electron tomography. They identify a role for d...

www.nature.com

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Jonathan Friedman @labfriedman.bsky.social · Feb 7

Congrats on the beautiful discovery! Awesome to see how this story has progressed. And yes, nice to have some positive news this week!

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