Leticia Kawano-Dourado
@leticiakawano.bsky.social
1.3K followers 56 following 340 posts
Physician • Trialist • Guideline methodologist | Evidence-based metabolic health & T2D reversal enthusiast Posting about: methodology, RCTs, #metabolichealth #Brazil, #Portugal #womenInMedicine, #HumanRights, #meditation
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Reposted by Leticia Kawano-Dourado
magicevidence.bsky.social
At MAGIC, we turn the best evidence into trustworthy guidance to improve patient care.

💡 #MAGICapp powers this process — a digital platform to build, publish, and update clinical practice #guidelines.

😎 Backed by a global network of leading methodologists.

magicevidence.org
Reposted by Leticia Kawano-Dourado
leticiakawano.bsky.social
In my #Krav class I’m the only woman (besides the instructor). However, women are the main targets of violence — 1 in 3 face it in life. I train hard, for myself and to inspire my daughter 🧑‍🧒‍🧒and her friends which is already happening 🫶
Reposted by Leticia Kawano-Dourado
magicevidence.bsky.social
Come hear @leticiakawano.bsky.social share her 2️⃣ favorite features in #MAGICapp 💥
Leticia is a guideline developer who first used MAGICapp as Clinical Chair of the WHO guideline on COVID-19, & later as a methodologist with the BMJ Rapid Recs,

book 🗓️ a demo here: forms.monday.com/forms/baaf06...
leticiakawano.bsky.social
How can evidence-based medicine #EBM guide decisions on hormone therapy (HT) for #menopause &
#perimenopause?

Have a look at this a conversation with @guyattgh.bsky.social exploring the particular context of HT to address irritability, brain fog 🧠, and sleep 😴🔥

youtu.be/2SN6yxb8KTU?...
[English] Hormone Therapy for Menopause & Evidence-Based Medicine #EBM
YouTube video by RenovaMeta
youtu.be
leticiakawano.bsky.social
Had such a great time recording these snippets with you, @guyattgh.bsky.social Beyond the fun, I’m deeply grateful for your mentoring and friendship over these past five years—time really does fly. Your guidance has truly shaped me into a better clinician. #EBM
leticiakawano.bsky.social
Behind the scenes with @guyattgh.bsky.social , where we trade some of academia’s pomp & circumstance 👑for a bit of humor 😎😅
But wait the topic is serious (shared decision-making on hormone therapy for #menopause, through the lens of #EBM).
Stay tuned for the full conversation 🤩
leticiakawano.bsky.social
One of the best parts of in-person events is the chance to actually meet *in person* the colleagues you’ve been working with from afar.
These moments remind me that collaboration is not just about outputs, but also about people: I need this! #GIN2025
@guyattgh.bsky.social @lisheyu.bsky.social
leticiakawano.bsky.social
Why I never skip the gym when traveling for conferences:
Endorphins first, sharper mind after.
Healthspan is built choice by choice, day by day. Consistency matters
leticiakawano.bsky.social
With rising violence against women 🤷‍♀️, learning to neutralize a threat is more than self-defense 💥 it’s reclaiming agency, while investing in healthspan.
Training #KravMaga adds explosiveness (fast-twitch fiber resilience), ballance & coordination under stress #LoveThat
leticiakawano.bsky.social
Honored to celebrate 🥳 the 1st anniversary of Público 🇧🇷 Brasil, nested within Público — one of Portugal’s 🇵🇹 leading newspapers. In 2025, Público Brasil reached over 2M views, amplifying the voice of the Brazilian community in Portugal.

www.publico.pt/autor/letici...
leticiakawano.bsky.social
Kinda scary you wanna say right?
(“Having fun” where there’s no room for fun?)
leticiakawano.bsky.social
Box jumps 💥aren’t just about performance😎. Research shows high-impact jumps increase hip bone mineral density and recruit type II muscle fibers — the ones we lose fastest with age #perimenopause #menopause health prevention 😍
Refs: PMID: 37790374, 39822926, 37748300;
leticiakawano.bsky.social
1/ 🇵🇹 Immigrant Residency by Decree = Fragile Ground

Crossing back into #Portugal after weeks in 🇧🇷 brought discomfort. The operational backlog in processing residency permits, with a record influx of immigrants in 🇵🇹, means that many live under temporary decrees rather than secure documentation +
leticiakawano.bsky.social
Spotted at Brasília #Brazil airport 👀😅
“Epic journeys begin with a warm welcome” — says the New York tourism ad, under the gaze of 🗽 the Statue of Liberty.

Hard not to read it with irony, given how warm the US reception often feels for foreigners lately…🤌🤯
Reposted by Leticia Kawano-Dourado
leticiakawano.bsky.social
8/ #Menopausecare has long been trapped between rigid protocols and “trial-and-error.” N-of-1 trials offer a third way: science, but personal.
It’s time we move beyond averages—and start building evidence that begins with the individual ♥️
End
Reposted by Leticia Kawano-Dourado
erictopol.bsky.social
What I love about interferons is their simplicity ;-)
But seriously a great @cellcellpress.bsky.social new review of IFNs that are our 1st line of defense vs infections and have a critical role in many inflammatory an autoimmune diseases www.cell.com/cell/fulltex...
leticiakawano.bsky.social
8/ #Menopausecare has long been trapped between rigid protocols and “trial-and-error.” N-of-1 trials offer a third way: science, but personal.
It’s time we move beyond averages—and start building evidence that begins with the individual ♥️
End
leticiakawano.bsky.social
7/ That would create not only personalized care but a collective resource: thousands of N-of-1s, aggregated into patterns, refining guidelines in real-time. Ping @guyattgh.bsky.social
leticiakawano.bsky.social
6/ Blue sky 🦋 thinking: What if every woman had access to a simple digital tool to run her own N-of-1 trial—logging symptoms, integrating wearables, feeding back into shared databases?
a poster for the great shows a woman with blonde hair
ALT: a poster for the great shows a woman with blonde hair
media.tenor.com
leticiakawano.bsky.social
5/ This approach could be a paradigm shift in #menopause #perimenopause care:
• More precise tailoring of hormone therapy
• Better alignment with patient values
• Filling in the evidence gap in #HRT
leticiakawano.bsky.social
4/ Imagine a woman trying two hormone therapy regimens, or HT vs. non-hormonal options, with systematic monitoring of sleep, cognition, metabolic markers, or quality of life.
the man is wearing a suit and tie and clapping his hands .
ALT: the man is wearing a suit and tie and clapping his hands .
media.tenor.com
leticiakawano.bsky.social
3/ An N-of-1 trial is a structured way to test therapies within a single patient. Instead of “one-size-fits-all,” it’s personalized evidence: alternating treatment periods, careful symptom tracking, shared decision-making (when interventions & outcomes allow it)
a dog wearing sunglasses is sitting in a car with a man .
ALT: a dog wearing sunglasses is sitting in a car with a man .
media.tenor.com