Lightnews — Scholar-powered news

Licheng Zou

@lichengzou.bsky.social

130 followers 430 following 5 posts

Theoretical neuroscience doctoral researcher from Fred Wolf's group at MPI-DS/ MSc from U. Amsterdam/ BSc from SJTU Web: https://lichengzou0509.github.io/Academic-CV/

lichengzou0509.github.io

Posts Media Videos Starter Packs

Licheng Zou @lichengzou.bsky.social · Aug 2

Thanks Bastian :)

Reposted by Licheng Zou

Jens-Bastian Eppler @j-b-eppler.bsky.social · Aug 1

Great new paper by my colleagues Gloria & Alex, and @lichengzou.bsky.social. Hebbian plasticity accounts for much of representational drift: Drift is ongoing memory storage, not noise. Also reconciles contradictory findings on stability after repeated exposure.

www.nature.com/articles/s41...
🧠🧪

Representational drift as the consequence of ongoing memory storage - Scientific Reports

Scientific Reports - Representational drift as the consequence of ongoing memory storage

www.nature.com

1 3 9

Reposted by Licheng Zou

Blake Richards @tyrellturing.bsky.social · Apr 8

BTSP, but not STDP, can account for place field changes in hippocampus, out in Nature Neuroscience today:

www.nature.com/articles/s41...

🧠📈 🧪

Synaptic plasticity rules driving representational shifting in the hippocampus - Nature Neuroscience

Madar et al. report that behavioral timescale synaptic plasticity (BTSP), not spike-timing-dependent plasticity, explains heterogeneous place fields shifting in the hippocampus. The probability of BTS...

www.nature.com

17 66

Reposted by Licheng Zou

Jorge Mejias @jorgefmejias.bsky.social · Mar 18

Please spread the word!! We are accepting applications for the Cold Spring Harbor Asia Computational and Cognitive Summer School in Suzhou, China. Dates: June 29 to July 20 of 2025. Application deadline: March 31. #computationalneuroscience. For the top three reasons to attend, see thread below:

3 7 14

Reposted by Licheng Zou

Joao Barbosa @jbarbosa.org · Mar 13

Most neuroscience research is exploratory: they search for *something* rather than testing a hypothesis. It's harking. I used to see that as a problem, but not anymore. The 1st papers generate hypotheses; the real testing comes later. Science only make sense collectively, not individually.

Dan Goodman @neural-reckoning.org · Mar 13

When I read research papers that are the result of very expensive work (experiments or simulations) I always want to know: how could this project have possibly ended with a null result? And is there an argument in this paper that compares the actual result to this null? If not, I'm very suspicious.

1 4 25

Reposted by Licheng Zou

Neuron @cp-neuron.bsky.social · Feb 24

Universal statistics of hippocampal place fields across species and dimensionalities

Mainali et al. show that a simple mathematical model explains recent observations of heterogeneous and irregular spatial responses in the hippocampus in large environments. The model unifies observations from environments of varying sizes and dimensions…

dlvr.it

2 4 22

Reposted by Licheng Zou

Jens-Bastian Eppler @j-b-eppler.bsky.social · Jan 6

Our new preprint: We found that during representational drift co-activation of neuron pairs is predictive of future effective connectivity. Drift is - in parts - just Hebbian plasticity. But we also need a stochastic process to account for our observations.

doi.org/10.1101/2025...

8 22

Licheng Zou @lichengzou.bsky.social · Dec 5

Congrats!

Licheng Zou @lichengzou.bsky.social · Dec 4

👋
www.biorxiv.org/content/10.1...

Representational drift as the consequence of ongoing memory storage

Memory systems with biologically constrained synapses have been the topic of intense theoretical study for over thirty years. Perhaps the most fundamental and far-reaching finding from this work is th...

www.biorxiv.org

1 2

Reposted by Licheng Zou

Grace Lindsay @neurograce.bsky.social · Nov 25

Sometimes I think the most important thing a computational neuroscientist can do to encourage acceptance of their work in the broader experimental community is just to plot their model data in the exact same way the relevant experimental data was plotted. It's very affecting!

5 10 100

Reposted by Licheng Zou

PessoaBrain @pessoabrain.bsky.social · Nov 25

𝗧𝗵𝗲 𝗺𝗼𝘀𝘁 𝗯𝗮𝘀𝗶𝗰 𝗶𝗻𝘁𝗿𝗼𝗱𝘂𝗰𝘁𝗶𝗼𝗻 𝘁𝗼 𝗳𝗠𝗥𝗜 𝗻𝗲𝘁𝘄𝗼𝗿𝗸𝘀.

Please, absolutely no equations, think of someone math phobic. Much better if a paper. thanks
#neuroscience

4 3 27

Licheng Zou @lichengzou.bsky.social · Nov 22

Would be great, may be some brainstorming via Slack

Licheng Zou @lichengzou.bsky.social · Nov 22

Disagree too, but the phenomenon that off-context experience stabilizes spatial drift but not rate drift is interesting. I also think that the framework proposed by Devalle et al. can explain this (I’ve told Alex about my thoughts :)