Lightnews — Scholar-powered news

Reposted by Lindsey Kennedy

Research at Sinai Health @sinaihealth.bsky.social · 2d

We are still accepting applications for Principal Investigator positions in:

🔬Biomedical Discovery Research
➡️ apply.interfolio.com/172703

🧬 Population Health Data Science
➡️ apply.interfolio.com/172529

Join our vibrant scientific community in the ❤️ of Toronto!

🗓️ Apply by October 20, 2025.

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Reposted by Lindsey Kennedy

Bill Hanage @billhanage.bsky.social · Sep 4

Last respiratory virus season 278 children in the US died of influenza, more than any year since 2009.

The majority were previously healthy, but 90% had *not* received a flu vaccine.

Facts are stubborn things

www.nytimes.com/2025/09/04/h...

Whistle-Blower Complaints Detail Tension Over Vaccines at N.I.H.

www.nytimes.com

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Reposted by Lindsey Kennedy

Amy Maxmen, PhD @amymaxmen.bsky.social · Sep 4

"Once trusted experts are removed and advisory bodies are stacked, the results are predetermined. That isn’t reform. It is sabotage."

Susan Monarez WSJ op-ed www.wsj.com/opinion/robe...

Opinion | Robert F. Kennedy Jr., the CDC and Me

I was fired after 29 days because I held the line and insisted on rigorous scientific review.

www.wsj.com

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Reposted by Lindsey Kennedy

Amy Maxmen, PhD @amymaxmen.bsky.social · Sep 4

NIH whistleblowers say HHS manipulated the grant review process to undermine vaccines. @nytimes.com www.nytimes.com/2025/09/04/h...

"The agency then added layers of political review to the grant-making process that would rule out any research at odds with Mr. Kennedy’s “scientifically unsupported position that vaccines caused harm, including autism in children,” the complaints say.

Even as it cut some vaccine research, the complaints said, the health department awarded $500 million in May to a universal vaccine project that many scientists said relied on badly outdated technology. "

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Lindsey Kennedy @livernotfighter.bsky.social · Sep 4

Me with my recent writing

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Lindsey Kennedy @livernotfighter.bsky.social · Aug 22

Circling back to this paper in CMGH from earlier this year on the generation & functionality of human intestinal organoids

Very timely read for #GIsky as the NIH & FDA are prioritizing new approach methodologies (NAMs) like this

www.cmghjournal.org/article/S235...

Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem Cells

Organs of the gastrointestinal tract contain tissue-resident immune cells that function during tissue development, homeostasis, and disease. However, most published human organoid model systems lack r...

www.cmghjournal.org

Lindsey Kennedy @livernotfighter.bsky.social · Aug 22

Incredibly upsetting and infuriating

Our biomedical enterprise is being absolutely tanked by this administration

Science Magazine @science.org · Aug 22

In a major blow to scientists who had NIH grants terminated by the Trump administration, the U.S. Supreme Court has told the government it can refuse to restore $783 million in federal research funding. https://scim.ag/45R0QWZ

Supreme Court upholds Trump cancellation of NIH grants

Justices rule lower court had no authority to compel restoration hundreds of studies on diversity, transgender health, and other sensitive topics

scim.ag

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Lindsey Kennedy @livernotfighter.bsky.social · Aug 22

Important info for researchers and grant writers:

New statement from the NIH Director discussing the priorities of the agency - these are unsurprising considering the news from the past few months

www.nih.gov/about-nih/ni...

Advancing NIH’s Mission Through a Unified Strategy

NIH is moving toward a unified strategy that aligns our priorities and funding approaches to fulfill this commitment.

www.nih.gov

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Lindsey Kennedy @livernotfighter.bsky.social · Aug 21

Did I miss a major NIH announcement? I was working on an R01 for a NOSI and just got word it will expire early Sept 2025 when the original expiration date was Sept 2027. I just checked funding opportunities and it looks like most (if not all) active NOSIs are set to expire this fall?

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Reposted by Lindsey Kennedy

Jeremy Berg @jeremymberg.bsky.social · Aug 21

New article in Research Professional News

[Sorry about the paywall]

www.researchprofessionalnews.com/rr-news-usa-...

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NIH staff ordered to re-evaluate all grants immediately - Research Professional News

Research not aligned with new priorities may be terminated, warns agency chief Jay Bhattacharya

www.researchprofessionalnews.com

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Reposted by Lindsey Kennedy

Carl Zimmer @carlzimmer.com · Aug 20

RFK Jr. Vowed to Find the Environmental Causes of Autism. Then He Shut Down Research Trying to Do Just That. Story by @fastlerner.bsky.social www.propublica.org/article/rfk-...

RFK Jr. Vowed to Find the Environmental Causes of Autism. Then He Shut Down Research Trying to Do Just That.

While touting a $50 million initiative to identify the causes of autism, Robert F. Kennedy Jr. is helping lead an administration that is rolling back protections against pollution and toxic chemicals,...

www.propublica.org

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Reposted by Lindsey Kennedy

American Society of Hematology @ash.hematology.org · Aug 19

This year the ASH Bridge Grant is funding 25 scientists with $3.75M, 5X more than last year, to keep hematology research moving forward. Congratulations to the recipients! https://bit.ly/3HJ51Ma

#HemeSky #MedSKy #ASHAwards

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Reposted by Lindsey Kennedy

Terence Tao @teorth.bsky.social · Aug 18

I wrote an op-ed on the world-class STEM research ecosystem in the United States, and how this ecosystem is now under attack on multiple fronts by the current administration: newsletter.ofthebrave.org/p/im-an-awar...

I’m an award-winning mathematician. Trump just cut my funding.

The “Mozart of Math” tried to stay out of politics. Then it came for his research.

newsletter.ofthebrave.org

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Lindsey Kennedy @livernotfighter.bsky.social · Aug 19

During acute pancreatitis, the body produces its own protective molecule - lactate💪

An unlikely protector, lactate encourages anti-inflammatory activity to facilitate pancreatic repair🛡️

🧪

www.cmghjournal.org/article/S235...

Lactate Facilitates Pancreatic Repair Following Acute Pancreatitis by Promoting Reparative Macrophage Polarization

During acute pancreatitis (AP), glycolysis is enhanced. The upregulation of glycolysis increases the level of metabolite lactate. Lactate has been shown to facilitate tissue repair across various path...

www.cmghjournal.org

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Reposted by Lindsey Kennedy

Carl Zimmer @carlzimmer.com · Aug 19

How to recognize shoddy studies that claim to link vaccines and autism. Essay by @unbiasedscipod.bsky.social Gift link: nyti.ms/3UUNrIp

Opinion | The Playbook Used to ‘Prove’ Vaccines Cause Autism (Gift Article)

Data can easily be manipulated to show causation that doesn’t exist.

nyti.ms

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Reposted by Lindsey Kennedy

STAT @statnews.com · Aug 18

“Kennedy would be less hazardous if he decided to do cardiac surgery. Then he would kill people only one at a time,” writes former CDC Director William Foege.
www.statnews.com/2025/08/18/r...

Former CDC Director William Foege: How public health can fight back in a time of dangerous nonsense

“Kennedy would be less hazardous if he decided to do cardiac surgery. Then he would kill people only one at a time,” writes former CDC Director William Foege.

www.statnews.com

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Reposted by Lindsey Kennedy

Richard M. Carpiano, PhD, MPH @rmcarpiano.medsky.social · Aug 18

By @rickabright.bsky.social, former Director of BARDA...
🛟medsky 🧪 health policy sociology polisky idsky 😷

Screenshot from the linked Aug. 17, 2025 NY Times' opinion piece by Dr. Rick Bright:

"The Department of Health and Human Services recently announced it would wind down 22 mRNA vaccine development projects under the Biomedical Advanced Research and Development Authority, or BARDA, halting nearly $500 million in investments. This decision undercuts one of the most significant medical advances in decades, technology that could protect millions more people from the threats ahead.

I know the stakes because I was BARDA’s director when the United States made the decision to invest heavily in mRNA. That investment did not begin with Covid-19. It began in 2016, when we faced the Zika virus outbreak. We needed a way to design a vaccine in days, not years, to protect pregnant women and their babies from devastating birth defects. Older vaccine approaches were too slow. The solution was mRNA: a flexible, rapid-response technology that could be reprogrammed for any pathogen once its genetic sequence was known. That early investment laid the groundwork for the lightning-fast Covid-19 response four years later."

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Lindsey Kennedy @livernotfighter.bsky.social · Aug 18

Dear #LiverSky #HepatoSky researchers:

PSC Partners grant cycle is now open! The deadline for your LOI is December 1, 2025

Need help crafting your grant? I offer editing services to help strengthen your proposal. Let's work together to make your work stand out!

pscpartners.org/research/res...

PSC Grant Application | Liver Research Grants | PSC Partners Seeking a Cure

Are you researching PSC? Do you need your medical research funded? At PSC Partners, we award grants to researchers answering important questions related to PSC. Apply.

pscpartners.org

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Lindsey Kennedy @livernotfighter.bsky.social · Aug 15

❓Shifts in cell metabolism drive liver cancer - but what are the mechanisms?

🎯This study found that a pathway (hexosamine biosynthetic pathway) may play a role in liver cancer progression

www.cmghjournal.org/article/S235...

The Role of the Hexosamine-Sialic Acid Metabolic Pathway Mediated by GFPT1/NANS in c-Myc-Driven Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) frequently involves metabolic reprogramming, which promotes oncogenesis and metastasis. However, the underlying molecular mechanisms remain insufficiently explored. In t...

www.cmghjournal.org

Reposted by Lindsey Kennedy

Jeremy Berg @jeremymberg.bsky.social · Aug 15

Today, Bhattacharya sent a document entitled

"NIH Priorities and Internal Review of Intramural and Extramural Programs"

to Institute and Center Directors and other leaders.

I am trying to get a clean copy.

These "Priorities" will likely be "Agency Priorities" for grant funding and termination.

a cartoon character from south park is holding a puppet that says pay attention

ALT: a cartoon character from south park is holding a puppet that says pay attention

media.tenor.com

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Reposted by Lindsey Kennedy

Physicians for a Healthy Democracy @physiciandemocracy.medsky.social · Aug 15

Please sign and share our petition to remove RFK Jr.

www.change.org/p/rfk-jr-mus...

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Lindsey Kennedy @livernotfighter.bsky.social · Aug 14

🚨23% of ulcerative colitis patients w/ total abdominal colectomy w/ ileal pouch-anal anastomosis have pouch failure
❓Why?
🎯Post-procedure chronic inflammation & immune cell activity may be risk factors

@aga-cmgh.bsky.social #GIsky

www.sciencedirect.com/science/arti...

Histopathologic Evaluation and Single-cell Spatial Transcriptomics of the Colon Reveal Cellular and Molecular Abnormalities Linked to J-Pouch Failure in Patients With Inflammatory Bowel Disease

Total abdominal colectomy (TAC) with a staged ileal pouch-anal anastomosis (IPAA) is a common surgical treatment for ulcerative colitis (UC). However,…

www.sciencedirect.com

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Reposted by Lindsey Kennedy

Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · Aug 14

"NOFOs will no longer be included in the weekly NIH Guide Table of Contents subscription emails. You can use Grants.gov subscription services to receive notifications of new NIH funding opportunities." 🧪

grants.nih.gov/grants/guide...

Home | Grants.gov

Grants.gov

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Lindsey Kennedy @livernotfighter.bsky.social · Aug 14

Both applications are due on September 18th, so about 1 month away! If you need help preparing an application, I am available for very small contract projects, like grant editing :)

Lindsey Kennedy @livernotfighter.bsky.social · Aug 14

$100k over 2 years to an established PI working on novel approaches in gastric cancer

gastro.org/research-and...

AGA-R. Robert & Sally Funderburg Research Award in Gastric Cancer

This award provides $50,000 per year for two years (totaling $100,000) to an established investigator working on novel approaches in gastric cancer research.

gastro.org

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