Elizabeth Stuart
@lizstuart.bsky.social
5.5K followers 290 following 44 posts
Statistician; Professor and Chair @JHUBiostat @JohnsHopkinsSPH, w/links to @SREESociety, @AmericanHealth. Oh, & spouse, mom, runner, traveler.
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Reposted by Elizabeth Stuart
publichealthpod.bsky.social
Does taking Tylenol during pregnancy cause autism in children?

@bklee.bsky.social and @lizstuart.bsky.social break down the science of causality on Public Health On Call 🎧 podcast.publichealth.jhu.edu/953-interpre...
lizstuart.bsky.social
Starting in a couple of hours; join us!
jhalacritycenter.bsky.social
Attend the Johns Hopkins ALACRITY Center’s Advanced Methods for Mental Health Services Research Webinar Series on September 17th from 10:30 a.m. - Noon.

Michael Rosenblum, PhD, MS and Joshua Betz, MS will discuss covariate adjustment in randomized trials.

jhjhm.zoom.us/webinar/regi...
photos of Michael A. Rosenblum, PhD, MS and Joshua Betz, MS, who will be presenting on Covariate Adjustment in Randomized Trials at the September 17th Advanced Methods for Mental Health Services Research Webinar.
lizstuart.bsky.social
So fun to come across this!

It has been an honor and joy to work with Grace on topics that include proximal causal inference, electronic health records, and measurement error. She is a careful and excellent researcher, and an amazing team member!
lizstuart.bsky.social
This was an incredible story to hear on my run this morning and has stayed with me. Meaningful, interesting, and inspiring.
neillewisjr.bsky.social
This Radiolab episode is one of the most beautiful and moving pieces of science communication I've come across in a long time.

Do yourself a favor and take some time to listen to this story of astrophysicist Charity Woodrum, and what she's learned from her work and life
radiolab.org/podcast/gala...
Galaxy Quenching
In the midst of unthinkable grief, an unthinkable discovery.
radiolab.org
lizstuart.bsky.social
Yes, fantastic messages -- I'm glad you wrote all of this down!
lizstuart.bsky.social
I'm looking forward to the conversations and learning at #JSM2025!
lizstuart.bsky.social
I appreciate the push for research at the end of the story about AI + education. But it doesn't clarify who will pay or do that needed research -- with the gutting of the federal education research agency (IES) it's not clear there will be unbiased groups to do it.

www.nytimes.com/2025/07/09/b...
A Classroom Experiment
www.nytimes.com
lizstuart.bsky.social
I am grateful for this coverage. Fiona is a friend and sadly just one example of many devoted public servants (who I know personally to be deeply committed, smart, and caring) whose expertise we are currently losing from the government.
joshuasweitz.bsky.social
Profile and interview of Fiona Havers by @apoorvanyt.bsky.social now out in the NYT. A must-read on the loss of experts and expertise. 🎁 link

www.nytimes.com/2025/06/18/h...
lizstuart.bsky.social
I was SO sad that my own session conflicted with this one!
lizstuart.bsky.social
@noahgreifer.bsky.social was my post-doc and I cannot recommend him more highly if you need a super smart statistical consultant / programmer. He is the force behind MatchIt, cobalt, and other packages, and is also just a fantastic team member.
noahgreifer.bsky.social
Starting to look like I might not be able to work at Harvard anymore due to recent funding cuts. If you know of any open statistical consulting positions that support remote work or are NYC-based, please reach out! 😅
lizstuart.bsky.social
Excited for what will be a flash trip to New England in mid-June for the AI + precision medicine conference in Portland, ME, followed by the Society for Epi Research in Boston! Join me at both!
lizstuart.bsky.social
My daughter was taking the same exam today! I kind of love the coordinated timing all around the country and the idea of a bunch of kids all sitting down for the tests in a coordinated timing kind of way.
lizstuart.bsky.social
Great way to learn the basics of policy trial emulation and the importance of careful study design for health policy!
jhalacritycenter.bsky.social
If you missed the latest Advanced Methods for Mental Health Services Research Webinar, "Target Trial Emulation for Evaluating Mental Health Policy" from Nicholas J. Seewald, Ph.D., don't worry! You can watch it on the JH ALACRITY Center's YouTube channel: youtu.be/DAXfp8X9ba8?...
Target Trial Emulation for Evaluating Mental Health Policy
YouTube video by JHU ALACRITY Center
youtu.be
lizstuart.bsky.social
“Scale is not a substitute for scrutiny” may be my new favorite quote. Thanks @adamjkucharski.bsky.social!
lizstuart.bsky.social
This is so important. And especially in non experimental studies where bias - not variance - is the first order concern.
adamjkucharski.bsky.social
The larger the dataset, the larger the false sense of confidence - if bias is baked in, size just makes a flawed measurement more convincing.

Xiao-Li Meng has called it the big data paradox: 'The bigger the data, the surer we fool ourselves.'

In other words, scale isn’t a substitute for scrutiny.
Statistical paradises and paradoxes in big data (I): Law of large populations, big data paradox, and the 2016 US presidential election
Statisticians are increasingly posed with thought-provoking and even paradoxical questions, challenging our qualifications for entering the statistical paradises created by Big Data. By developing measures for data quality, this article suggests a framework to address such a question: “Which one should I trust more: a 1% survey with 60% response rate or a self-reported administrative dataset covering 80% of the population?” A 5-element Euler-formula-like identity shows that for any dataset of size $n$, probabilistic or not, the difference between the sample average $\overline{X}_{n}$ and the population average $\overline{X}_{N}$ is the product of three terms: (1) a data quality measure, $\rho_{{R,X}}$, the correlation between $X_{j}$ and the response/recording indicator $R_{j}$; (2) a data quantity measure, $\sqrt{(N-n)/n}$, where $N$ is the population size; and (3) a problem difficulty measure, $\sigma_{X}$, the standard deviation of $X$. This decomposition provides multiple insights: (I) Probabilistic sampling ensures high data quality by controlling $\rho_{{R,X}}$ at the level of $N^{-1/2}$; (II) When we lose this control, the impact of $N$ is no longer canceled by $\rho_{{R,X}}$, leading to a Law of Large Populations (LLP), that is, our estimation error, relative to the benchmarking rate $1/\sqrt{n}$, increases with $\sqrt{N}$; and (III) the “bigness” of such Big Data (for population inferences) should be measured by the relative size $f=n/N$, not the absolute size $n$; (IV) When combining data sources for population inferences, those relatively tiny but higher quality ones should be given far more weights than suggested by their sizes. Estimates obtained from the Cooperative Congressional Election Study (CCES) of the 2016 US presidential election suggest a $\rho_{{R,X}}\approx-0.005$ for self-reporting to vote for Donald Trump. Because of LLP, this seemingly minuscule data defect correlation implies that the simple sample proportion of the self-reported voting preference for Trump from $1\%$ of the US eligible voters, that is, $n\approx2\mbox{,}300\mbox{,}000$, has the same mean squared error as the corresponding sample proportion from a genuine simple random sample of size $n\approx400$, a $99.98\%$ reduction of sample size (and hence our confidence). The CCES data demonstrate LLP vividly: on average, the larger the state’s voter populations, the further away the actual Trump vote shares from the usual $95\%$ confidence intervals based on the sample proportions. This should remind us that, without taking data quality into account, population inferences with Big Data are subject to a Big Data Paradox: the more the data, the surer we fool ourselves.
projecteuclid.org
lizstuart.bsky.social
Great way to learn the basics of policy trial emulation for free! Paper here: pubmed.ncbi.nlm.nih.gov/39374529/
lizstuart.bsky.social
This has been one of the most meaningful and rewarding (and sobering) collaborations I have been involved in, especially the integration of advanced stat methods and deep substantive expertise. Crucial empirical data and results that we hope can inform policy discussions.
jama.com
JAMA @jama.com · Feb 13
🧵 US states that implemented abortion bans saw higher than expected infant mortality rates, with larger increases among Black infants and those in southern states, according to this analysis of US national vital statistics data from 2012–2023.

ja.ma/4aVchPn

#MedSky
Figure 1.  Trends in Biannual US Infant Mortality Rates, 2012-2023
lizstuart.bsky.social
Make sure it's done multiple times -- otherwise imputation will make estimates appear more precise than they really are.
lizstuart.bsky.social
One add'l insight is that in some contexts a "missing data indicator" approach is actually okay (that's what twang does in implementation), and even if you do MICE [with outcomes and treatment included too!] it might make sense to include missing data indicators, as they may carry info about people.
Reposted by Elizabeth Stuart
mcpli.bsky.social
The WSJ editorial board out with a piece today opposing confirmation of RFK, Jr.

www.wsj.com/opinion/rfk-...
lizstuart.bsky.social
Sad to be missing the opportunity to cross country ski in DC but can’t really complain about being at #ICHPS. Already have run into many friends and ran on the beach!
Reposted by Elizabeth Stuart
lizstuart.bsky.social
Thank you for this thread; information like this is sorely needed. One quibble -- I would clarify that "massive study" does not always equal good evidence -- quality matters, not just sample size. Agree on the substance though; no rigorous evidence for a link between vaccines and autism!
lizstuart.bsky.social
That was Union station in DC.
lizstuart.bsky.social
There are worse places to have to be very early in the morning. Excited to spend the day talking causality at Penn!