Irfan Lodhi
@lodhilab.bsky.social
120 followers 120 following 6 posts
Professor of Medicine at Washington University| Studying lipid metabolism| Adipocyte Biology, BAT, Diabetes, NAFLD, Obesity, Peroxisomes| PhD UMICH
Posts Media Videos Starter Packs
Pinned
lodhilab.bsky.social
Happy to share our new paper in @nature.com led by staff scientist Xuejing Liu. We report identification of a UCP1-independent pathway of brown fat thermogenesis involving ATP-consuming metabolism of BCFA in peroxisomes. #Obesity #T2D
www.nature.com/articles/s41...
lodhilab.bsky.social
The neglected organelle
lodhilab.bsky.social
Thanks so much, Katsu! It’s been an incredible journey since our Clay lab days. So glad to have you and Babak @razanilab.bsky.social as co-authors and long-time collaborators. Couldn’t have asked for better colleagues and friends along the way.
Reposted by Irfan Lodhi
echouchani.bsky.social
First post here! Excited to share a new paper and online resource from our lab published today. We developed a mass spectrometry approach that leverages genetic diversity to systematically nominate functional relationships between metabolites and proteins.
www.nature.com/articles/s41...
Covariation MS uncovers a protein that controls cysteine catabolism - Nature
A mass spectrometry-based approach globally identifies protein regulators of metabolism and reveals the role of LRRC58 in controlling cysteine catabolism.
www.nature.com
lodhilab.bsky.social
Happy to share our new paper in @nature.com led by staff scientist Xuejing Liu. We report identification of a UCP1-independent pathway of brown fat thermogenesis involving ATP-consuming metabolism of BCFA in peroxisomes. #Obesity #T2D
www.nature.com/articles/s41...
Reposted by Irfan Lodhi
katsufunai.bsky.social
Channel 2, 4, 5, and 13 as well as a few local newspapers reached out to me today regarding our study on semaglutide we published in Cell Metabolism last week.

This interview is from NBC/KSL.
Weight loss drugs: Utah study in mice finds 'unexpected' effects
Weight loss drugs and muscle mass are at the center of a new Utah study.
ksltv.com
Reposted by Irfan Lodhi
Reposted by Irfan Lodhi
razanilab.bsky.social
Wondered how #adipocyte #fat release #lipid via #lipolysis in #fasting, cold exposure? Multi-year Razani lab effort in @jclinical-invest.bsky.social by postdoc maven Yu-Sheng Yeh identifies #lysosome lipolysis (LAL) as major way on par with known cytosolic route (ATGL)
jci.org/articles/view/185340
Reposted by Irfan Lodhi
Reposted by Irfan Lodhi
jinghughes.bsky.social
This is as good an introduction as any - the reason why I am here. #StandUpForScience. Nice to see you all.