Lone Hoffmann
lonehoffmann.bsky.social
Lone Hoffmann
@lonehoffmann.bsky.social
Medical physicist, Aarhus University Hospital
Reposted by Lone Hoffmann
Hella Sand looked at rigid v deformable reg for lung #reirradiation. Both performed well, with good inter-centre consistency, but less variation for DIR, especially for cumulative max dose. Results have driven recommendations in the CURE Lung reRT trial #radonc #medphys #ESTRO25
May 5, 2025 at 3:41 PM
Reposted by Lone Hoffmann
Isak Wahlsted led a national study of dose accumulation for #reirradiation: 8 diverse cases evaluated in all Danish RT centres

Image reg was consistent & high quality; but differences in a/b & tissue recovery gave substantial intercentre variation in cumulative dose #medphys #radonc #ESTRO25
May 5, 2025 at 3:41 PM
Sarah Eckholdt presenting the robustness results of the European phase III PROTECT trial showing very good compliance with the trial requirements on dose delivery
May 4, 2025 at 9:02 AM
Reposted by Lone Hoffmann
For even more #reirradiation highlights and discussion, join the dedicated conference WhatsApp group!
#ESTRO25 #medphys #radonc
May 3, 2025 at 5:30 AM
Reposted by Lone Hoffmann
Absolutely no difference in toxicity profiles between 66Gy and dose escalation; even when considering lower grade events or time profiles
(Major caveat: we’re only reporting toxicity up to 6 months at this point - but we’ve not seen any signals in the late toxicity so far either)
April 23, 2025 at 1:30 AM