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Alexander Lorenz @lorenzlab.bsky.social · 19d

The other one on how the misregulation of a key meiotic factor might affect genome stability tinyurl.com/pjxrvur9

MSc by Research: Does the mis-regulation of the meiotic HORMA-domain protein induce genome instability? at University of Aberdeen on FindAPhD.com

PhD Project - MSc by Research: Does the mis-regulation of the meiotic HORMA-domain protein induce genome instability? at University of Aberdeen , listed on FindAPhD.com

tinyurl.com

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Alexander Lorenz @lorenzlab.bsky.social · 19d

I am offering two MSc by Research opportunities in my laboratory (self-funded!), one on the human-pathogenic yeast Candidazyma auris tinyurl.com/ys8zexbv

MSc by Research: Harnessing Transposon Mutagenesis to Dissect Antifungal Drug Resistance in the Fungal “Superbug” Candidozyma auris at University of Aberdeen on FindAPhD.com

PhD Project - MSc by Research: Harnessing Transposon Mutagenesis to Dissect Antifungal Drug Resistance in the Fungal “Superbug” Candidozyma auris at University of Aberdeen , listed on Find...

tinyurl.com

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Alexander Lorenz @lorenzlab.bsky.social · Sep 1

Just arrived in Newcastle for the @gensocuk.bsky.social summer studentship workshop, looking forward to interesting science from early-career researchers #genetics

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Reposted by Alexander Lorenz

Schnittger Lab @schnittger-lab.bsky.social · Aug 25

Six more years—plus a lot of blood, sweat, and tears—later, we are thrilled to finally share it: a cytological framework of female meiosis in Arabidopsis!

www.biorxiv.org/content/10.1...

A cytological framework of female meiosis in Arabidopsis

Female and male meiosis often differ in many aspects, such as their duration and the frequency as well as the positioning of crossovers. However, studying female meiosis is often very challenging and ...

www.biorxiv.org

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Alexander Lorenz @lorenzlab.bsky.social · Aug 22

Very happy to have our preprint published in Microbiological Research now doi.org/10.1016/j.mi..., we had additional help from Steven during the revision to get this over the line @chitinette.bsky.social @theafg.bsky.social @uniofaberdeen.bsky.social

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Reposted by Alexander Lorenz

Genetics Society UK @gensocuk.bsky.social · Jul 24

Ready to shout BINGO! and learn something mind-blowing in the process? Join @genotripe.bsky.social for Genetics Bingo at the @edfringe.bsky.social, play actual bingo and find out some wild genetic facts!

📅 12th August
📍 The Stand 2

www.thestand.co.uk/performance/...

The Provocateurs: Genetics Bingo - The Stand Comedy Club

The Provocateurs: Genetics Bingo Hosted by comedian Susan Morrison. Ear wax – for some people, it is wet and smelly, for others it is dry and flaxy. And not ...

www.thestand.co.uk

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Reposted by Alexander Lorenz

Genetics Society UK @gensocuk.bsky.social · Jul 1

We’ve got some good news! The deadline to submit abstracts for our “Ancient #Genomes: Perspectives on Human Biology and Medicine” meeting has been extended to 31 July 2025. So if you were thinking about submitting, there’s still plenty of time!

genetics.org.uk/events/ancie...

Ancient genomes: perspectives on human biology and medicine | Genetics Society

It is our great pleasure to invite you to participate in the Autumn Meeting of the Genetics Society. This meeting will provide a unique forum to network and socialise with a wide cross-section of the ...

genetics.org.uk

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Alexander Lorenz @lorenzlab.bsky.social · Jun 19

My MSc students are getting to work ☺️

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Reposted by Alexander Lorenz

Genetics Society UK @gensocuk.bsky.social · May 15

Join us for our Anniversary Day and hear from:

Prof Josephine Pemberton (Genetics Society Medal)
Prof Kathy Niakan (Mary Lyon Medal)
Prof Gregory Radick (Haldane Lecture)
Prof Richard Durbin (Genomics keynote)
Rosie Parkin & Eldrian Tho (Student talks)

Registration: genetics.org.uk/events/genet...

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Reposted by Alexander Lorenz

Genetics Society UK @gensocuk.bsky.social · Apr 23

Welcome to Belfast! We're thrilled to kick off our spring conference: "Epigenetics: from mechanisms to diseases".

Get ready for groundbreaking science and inspiring talks! #Epigenetics2025

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Reposted by Alexander Lorenz

MAYosis @mayosis.bsky.social · Apr 7

We have a complete program !

meiosis.cornell.edu/mayosis2025/...

The #Mayosis25 seminar series will open with a tribute to Scott Hawley by @jeffsekelsky.bsky.social.

Congrats to all the selected speakers and we look forward to hearing about your fantastic science !

#Meiosis4ever

MAYosis 2025

meiosis.cornell.edu

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Alexander Lorenz @lorenzlab.bsky.social · Apr 18

Apparently my BSc project students enjoyed their time in my lab as much as I enjoyed supervising them

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Reposted by Alexander Lorenz

Diethard Mattanovich @dmattanovich.bsky.social · Mar 10

My lab @bokuvienna.bsky.social has an opening for a PhD on Synthetic Single Carbon Assimilation in Yeast.
Find details here www.circularbioengineering.at/jobsprogram2 - PhD 2.1 if you consider joining us within the Cluster of Excellence Circular Bioengineering

Cartoon of a metabolically engineered yeast cell recycling carbon in a spaceship

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Reposted by Alexander Lorenz

Oded Rechavi @odedrechavi.bsky.social · Mar 7

The truth is that the scientific process is horribly inefficient and wasteful. But the solution is NOT cutting funds and it’s NOT top down guidance of what should be studied. Instead, we should revolutionize how we publish and improve peer review.

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Alexander Lorenz @lorenzlab.bsky.social · Jan 22

Thanks for your message. We don't know enough about biocide selection in C. auris and how this affects its genetics and biology, so hard to tell.

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Alexander Lorenz @lorenzlab.bsky.social · Jan 15

we observe that these variants show little changes in biochemical and ultrastructural features of the cell wall, and that the moderate fitness trade-offs ultimately do not impinge on the pathogenicity potential of C. auris (in contrast to what has been reported for Candida albicans). 4/4

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Alexander Lorenz @lorenzlab.bsky.social · Jan 15

we show that these variants produce cross-resistance to other echinocandin drugs but moderate collateral sensitivity to other antifungals and cell wall stress (fitness trade-offs) 3/n

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Alexander Lorenz @lorenzlab.bsky.social · Jan 15

we show that caspofungin-resistant isolates harbour SNPs in the expected target gene FKS1 (FKS1-S639P and FKS1-S639Y variants) 2/n

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Alexander Lorenz @lorenzlab.bsky.social · Jan 15

In this manuscript we show that a caspofungin-sensitive C. auris clade II isolate can develop resistance against caspofungin during in vitro evolution under drug pressure (similar approaches were previously unsuccessful) 1/n

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Alexander Lorenz @lorenzlab.bsky.social · Jan 15

I posted this preprint to bioRxiv already before the holiday break and didn't have time to talk about it here yet www.biorxiv.org/content/10.1... 🧬🧫🔬 Work from two of my PhD students, Zoe and Sakinah, with help from Yixin & @chitinette.bsky.social

In vitro evolution of caspofungin resistance in Candidozyma auris via FKS1 hotspot I mutations results in moderate fitness trade-offs but no reduction in virulence

Resistance to echinocandins in the recently emerged pathogen Candidozyma auris (previously known as Candida auris ) poses significant clinical challenges. This study reports the in vitro evolution of ...

www.biorxiv.org

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Alexander Lorenz @lorenzlab.bsky.social · Jan 15

Only a few days left to apply!

Alexander Lorenz @lorenzlab.bsky.social · Dec 13

There is competitive #PhD funding for 4 years (eligibility criteria apply) to do a project on the human pathogen Candidozyma (Candida) auris dissecting the genetic basis of its antimicrobial resistance #AMR www.findaphd.com/phds/project... - pls repost

EASTBIO: Harnessing Transposon Mutagenesis to Dissect Antifungal Drug Resistance in the Fungal “Superbug” Candidozyma auris at University of Aberdeen on FindAPhD.com

PhD Project - EASTBIO: Harnessing Transposon Mutagenesis to Dissect Antifungal Drug Resistance in the Fungal “Superbug” Candidozyma auris at University of Aberdeen , listed on FindAPhD.com

www.findaphd.com

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Reposted by Alexander Lorenz

MAYosis @mayosis.bsky.social · Jan 15

Happy new year everyone!

We are please to announce the return of MAYosis in 2025!

Every Wednesday in May at 4pm CET, come hear the latest #meiosis4ever stories!

Abstract sub deadline: March 8 (end of day wherever you are)

meiosis.cornell.edu/mayosis2025/

MAYosis 2025

meiosis.cornell.edu

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Reposted by Alexander Lorenz

Andrew Lloyd @andrewhmlloyd.bsky.social · Jan 13

PhD Opportunity! Apply multiomics approaches to uncover how plants maintain fertility under heat stress. We're looking for enthusiastic applicants passionate about plant science! 🌾🧬🔬
Apply: bit.ly/TempResilien...
Deadline: 03.02.2025
#PhDPosition #PlantScience #CropImprovement

Project at Aberystwyth University: Decoding Heat Tolerance At Flowering: Using Multi-omics Approaches to Unlock Crop Resilience at University of Reading on FindAPhD.com

PhD Project - Project at Aberystwyth University: Decoding Heat Tolerance At Flowering: Using Multi-omics Approaches to Unlock Crop Resilience at University of Reading, listed on FindAPhD.com

bit.ly

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Reposted by Alexander Lorenz

Alexis Barr @alexisbarr.bsky.social · Dec 17

@mrc-lms.bsky.social is hiring! Are you looking to start your own research group? Come & join us!

Fantastic research, wonderful facilities & super supportive colleagues. Deadline 13th Jan.

Get on it!

lms.mrc.ac.uk/work/vacanci...

Programme Leader Track - MRC Laboratory of Medical Sciences

Programme Leader Track appointments are an open-ended contract, which comprises a six-year advanced career development scheme after which you will be considered for promotion to Programme Leader.

lms.mrc.ac.uk

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Alexander Lorenz @lorenzlab.bsky.social · Dec 13

There is competitive #PhD funding for 4 years (eligibility criteria apply) to do a project on the human pathogen Candidozyma (Candida) auris dissecting the genetic basis of its antimicrobial resistance #AMR www.findaphd.com/phds/project... - pls repost

EASTBIO: Harnessing Transposon Mutagenesis to Dissect Antifungal Drug Resistance in the Fungal “Superbug” Candidozyma auris at University of Aberdeen on FindAPhD.com

PhD Project - EASTBIO: Harnessing Transposon Mutagenesis to Dissect Antifungal Drug Resistance in the Fungal “Superbug” Candidozyma auris at University of Aberdeen , listed on FindAPhD.com

www.findaphd.com

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