@louiseheitzmann.bsky.social
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Postdoc at UCR working on the evolution of Y-linked genes expression in Microtus voles. Sex chromosomes, sexual polymorphism, sex determination, sex differentiation
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louiseheitzmann.bsky.social
🎉 PAPER OUT ! Happy to see another chapter of my PhD out in #MBE ! The African pygmy mouse flips the script on sex determination. Its multiple sex and neo-sex chromosomes 🤯 shape brain transcriptomes and drive sexual polymorphism, reflecting new evolutionary trajectories for sex-linked regions.
molbioevol.bsky.social
Heitzmann et al. compared brain transcriptomes of four sexual genotypes of the African pygmy mouse, showing how sex and neo-sex chromosomes impacted transcriptomes to reflect their transmission mode, evolutionary trajectories, and genomic conflicts.

🔗 doi.org/10.1093/molbev/msaf208

#evobio #molbio
MBE | Influence of Gonadal and Chromosomal Sex on the Brain Transcriptome in a Mouse Species with Natural Sex Reversal