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molbioevol.bsky.social
Molecular Biology and Evolution
@molbioevol.bsky.social
1K followers 35 following 240 posts
MBE publishes fresh insights into the patterns and processes that impact the evolution of life at molecular levels. 🔗 academic.oup.com/mbe 🏠 @official-smbe.bsky.social 🤝 @genomebiolevol.bsky.social #evobio #molbio #science #biology #societyjournal
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molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 7d
The October cover of Molecular Biology and Evolution features the work of Han et al., who investigated the origins of East Asian domestic pigs.

🔗 doi.org/10.1093/molbev/msaf214

#evobio #molbio #domestication
Molecular Biology and Evolution | October 2025 cover
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molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 2d
Lin et al. present a chromosome-level genome of Eden's whale to elucidate the speciation and taxonomy of balaenopterids; findings show Eden's whale is the sister species of Bryde's whale, sharing a common ancestor approximately 7.84 Mya.

🔗 doi.org/10.1093/molbev/msaf234

#evobio #molbio #whale
MBE | Chromosome-Level Genome Assembly of Eden's Whale Clarifies the Taxonomy and Speciation of Bryde's Whale Complex
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molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 2d
Kistler & Bedford analysed the evolution of human influenza virus from strains grown in chicken eggs for several generations for vaccine production.

🔗 doi.org/10.1093/molbev/msaf227

#evobio #molbio #virus #influenza
Seasonal Influenza Viruses Show Distinct Adaptive Dynamics During Growth in Chicken Eggs
Abstract. Human influenza viruses are grown in chicken eggs for vaccine production. Sequences of these egg-passaged viruses give us the opportunity to exam
doi.org
1 1
molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 2d
Goya & Greninger sequenced human parainfluenza virus genomes, with their findings highlighting distinct evolutionary histories of HPIV-2 and HPIV-4, raising hypotheses around complex Paramyxoviridae zoonotic events.

🔗 doi.org/10.1093/molbev/msaf217

#evobio #molbio #virus
Distinct Evolutionary Signatures of Human Parainfluenza Viruses 2 and 4 Reveal Host Antagonism Divergence and Phylogenetic Discordance
Abstract. Human parainfluenza virus 2 (HPIV-2) and human parainfluenza virus 4 (HPIV-4) are significant but underappreciated respiratory pathogens, particu
doi.org
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Reposted by Molecular Biology and Evolution
ecoevodom.bsky.social
Dominik Melville @ecoevodom.bsky.social · 2d
The extent to which closely related hosts share similar gut microbiota fascinates me. Work that truely stands out to me comes from @bperezlamarque.bsky.social and colleagues using process-based modelling over correlative approaches - a 'must' read #mevosky academic.oup.com/mbe/article/...
Phylogenetic Comparative Approach Reveals Evolutionary Conservatism, Ancestral Composition, and Integration of Vertebrate Gut Microbiota
Abstract. How host-associated microbial communities evolve as their hosts diversify remains equivocal: how conserved is their composition? What was the com
academic.oup.com
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molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 2d
Congratulations on this excellent article, Anastasia and team!
Reposted by Molecular Biology and Evolution
anaignatieva.bsky.social
Ana Ignatieva @anaignatieva.bsky.social · 5d
Delighted that our paper about the distribution of genomic spans of clades/edges in genealogies (ARGs), and using this for detecting inversions and other SVs (and other phenomena that cause local disruption of recombination) is out in MBE academic.oup.com/mbe/article/... (1/n)
The Length of Haplotype Blocks and Signals of Structural Variation in Reconstructed Genealogies
Abstract. Recent breakthroughs have enabled the accurate inference of large-scale genealogies. Through modelling the impact of recombination on the correla
academic.oup.com
4 37 60
molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 5d
@claudele.bsky.social et al. studied the fundamental question of how enzymatic activity emerges by focusing on type B dihydrofolate reductases, suggesting DfrB domains evolved rudimentary catalysis from a binding capacity.

🔗 doi.org/10.1093/molbev/msaf215

#evobio #molbio
From Binding to Catalysis: Emergence of a Rudimentary Enzyme Conferring Intrinsic Antibiotic Resistance
Abstract. How does enzymatic activity emerge? To shed light on this fundamental question, we study type B dihydrofolate reductases (DfrB), which were disco
doi.org
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Reposted by Molecular Biology and Evolution
jsantoyo.bsky.social
Javier Santoyo @jsantoyo.bsky.social · 5d
Introducing the Y-chromosomal Ancestral-like Reference Sequence—Improving the Capture of Human Evolutionary Information. #Ychromosome #EvolutionaryInformation #GeneticVariants #HumanGenome @molbioevol.bsky.social 🧬 🖥️
academic.oup.com/mbe/article/...
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molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 6d
Zhang et al. eccDNABase, a comprehensive and curated resource for browsing, searching, and analyzing Extrachromosomal circular DNAs across multiple species.

🔗 doi.org/10.1093/molbev/msaf223

#evobio #molbio #compbio
eccDNABase: A Comprehensive and High-Quality Database for Extrachromosomal Circular DNA
Abstract. Extrachromosomal circular DNA (eccDNA) refers to small, circular DNA molecules that originate from chromosomal sequences and are prevalent across
doi.org
1
molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 6d
Köksal et al. introduce the Y-chromosomal ancestral-like reference sequence to improve the detection of evolutionarily informative variants on the Y chromosome, and introduce the tool polaryzer to annotate variants in Y chromosome data

🔗 doi.org/10.1093/molbev/msaf222

#evobio #molbio
Introducing the Y-chromosomal Ancestral-like Reference Sequence—Improving the Capture of Human Evolutionary Information
Abstract. Reference sequences are essential for reproducible genetic analyses but are often chosen without regard to evolutionary relevance within the anal
doi.org
2 3
molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 6d
Fischer et al. characterize differences in gene network connectivity and density, suggesting that flexibility in gene coexpression relationships could promote evolvability.

🔗 doi.org/10.1093/molbev/msaf194

#evobio #molbio
Flexibility in Gene Coexpression at Developmental and Evolutionary Timescales
Abstract. The explosion of next-generation sequencing technologies has allowed researchers to move from studying single genes to studying thousands of gene
doi.org
2 4
molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 6d
Pang, Liu & Zhang combined theoretical analyses and simulations to evaluate the robustness of methods to detect gene flow in the face of rate variation across phylogenetic timescales.

🔗 doi.org/10.1093/molbev/msaf216

#evobio #molbio
Detecting Introgression in Shallow Phylogenies: How Minor Molecular Clock Deviations Lead to Major Inference Errors
Abstract. Recent theoretical and algorithmic advances in introgression detection, coupled with the growing availability of genome-scale data, have highligh
doi.org
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molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 6d
Great work, Sven and colleagues. Thank you for publishing your research with MBE!
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Reposted by Molecular Biology and Evolution
pierremarcdelaux.bsky.social
PM Delaux @pierremarcdelaux.bsky.social · 6d
...and three more fern genomes @molbioevol.bsky.social !

Not-so-static static lineages!

academic.oup.com/mbe/advance-...
Resolving the stasis-dynamism paradox: Genome evolution in tree ferns
Abstract. The paradox of evolutionary stasis and dynamism—how morphologically static lineages persist through deep geological periods despite environmental
academic.oup.com
6 18
Reposted by Molecular Biology and Evolution
turbokraken.bsky.social
Sven Gould @turbokraken.bsky.social · 13d
The evolution of land plants involved a charge-based adaption in the targeting sequences for #mitochondria and #chloroplasts and the origin of their de/phosphorylation.

#science 🧪

academic.oup.com/mbe/advance-...
Evolutionary refinement of mitochondrial and plastid targeting sequences coincides with the late diversification of land plants
Abstract. Plastids and mitochondria are key to plant survival and adaptation. The evolutionary progress of land plants (embryophytes) witnessed gene and ge
academic.oup.com
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Reposted by Molecular Biology and Evolution
alecarbone.bsky.social
Alessandra Carbone @alecarbone.bsky.social · 10d
We connected molecular signatures of selection with their mechanistic and functional relevance opening new ways of guiding experimental assays without requiring exhaustive testing of tens or hundreds of candidates.
Read in Molecular Biology and Evolution: academic.oup.com/mbe/advance-...
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molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 7d
The October cover of Molecular Biology and Evolution features the work of Han et al., who investigated the origins of East Asian domestic pigs.

🔗 doi.org/10.1093/molbev/msaf214

#evobio #molbio #domestication
Molecular Biology and Evolution | October 2025 cover
4 11
Reposted by Molecular Biology and Evolution
carmensomething.bsky.social
creature::carmen @carmensomething.bsky.social · 9d
Fascinating paper on ASD in humans compared to other mammals.

tl;dr - very roughly: we have evolved some fancy neurons and selected for reduced expression of asd-related genes (which do not seem to cause autism in other mammals)

academic.oup.com/mbe/article/...
General Principle of Neuronal Evolution Reveals a Human-Accelerated Neuron Type Potentially Underlying the High Prevalence of Autism in Humans | Molecular Biology and Evolution | Oxford Academic
Abstract. The remarkable ability of a single genome sequence to encode a diverse collection of distinct cell types, including the thousands of cell types f
academic.oup.com
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molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 8d
We have just hit our first 1,000 followers since joining Bluesky in April!

Thank you to all our followers, readers, and the authors of our articles for helping us promote the fantastic research published in Molecular Biology and Evolution!
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Reposted by Molecular Biology and Evolution
heche.bsky.social
Hengchi Chen @heche.bsky.social · 11d
Resolving the stasis-dynamism paradox: Genome evolution in tree ferns url: academic.oup.com/mbe/article/..., nice work from @52ying.bsky.social!
Resolving the stasis-dynamism paradox: Genome evolution in tree ferns
Abstract. The paradox of evolutionary stasis and dynamism—how morphologically static lineages persist through deep geological periods despite environmental
academic.oup.com
1 3
molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 12d
McDowell et al. find that melanopsin spectral sensitivity is constrained across mammalian species via molecular mechanisms that are substantially distinct from those of other opsins.

🔗 doi.org/10.1093/molbev/msaf158

#evobio #molbio #opsins
Spectral Tuning in Mammalian Melanopsins
Abstract. Melanopsin is a light-sensitive G-protein coupled receptor responsible for essential visual and non-visual light-mediated behaviors in mammals. H
doi.org
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molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 12d
Han et al. used genome data from ancient domestic pigs and wild boar from 5,800 BCE to 1,300 CE across China, confirming N. China as the domestication origin of modern East Asian pigs, and signatures of human management as early as 3,000 BCE.

🔗 doi.org/10.1093/molbev/msaf214

#evobio #molbio
MBE | Ancient Genomics Reveals the Origin, Dispersal, and Human Management of East Asian Domestic Pigs
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molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 13d
VBIO: Wie Pflanzen verrotten: Neue Methode entschlüsselt verborgene Zersetzer von Holz und Blatt

🔗 www.vbio.de/aktuelles/de...
Wie Pflanzen verrotten: Neue Methode entschlüsselt verborgene Zersetzer von Holz und Blatt
Wenn Millionen kleiner Organismen totes Pflanzenmaterial zersetzen, halten sie damit den globalen Kohlenstoffkreislauf in Gang. Um herauszufinden, welche molekularen Werkzeuge verschiedene Arten für d...
www.vbio.de
molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 13d
The Microbiologist: How plants rot: New method decodes hidden decomposers of wood and leaves

🔗 www.the-microbiologist.com/news/how-pla...
How plants rot: New method decodes hidden decomposers of wood and leaves
Researchers have developed a new method to identify the molecular tools that different species use to decompose dead plant material. Their analysis of over 18,000 species found that some invertebrates...
www.the-microbiologist.com
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molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 13d
Our recent article on fDOG a novel profile-based ortholog search tool, used to describe the taxonomic distribution of plant cell wall-degrading enzymes, has received attention of some news outlets. Check below ⬇️

Read the original article here: doi.org/10.1093/molb...

#evobio #molbio
Feature Architecture-Aware Ortholog Search With fDOG Reveals the Distribution of Plant Cell Wall-Degrading Enzymes Across Life
Abstract. The decomposition of plant material is a key driver of the global carbon cycle, traditionally attributed to fungi and bacteria. However, some inv
doi.org
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