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Lucid Scientific @lucidscientific.bsky.social · 1d

Our march through Europe continues with next week's European Association for Cancer Research Neuroscience Conference, held in Spain. Lucid's Mike Lu will be representing our booth, exhibiting our #Resipher device and other technologies. Stop by and say hi!

Event info >>> eacr.org/conference/c...

Lucid Scientific @lucidscientific.bsky.social · 5d

The study investigates the mechanism by which the ceramide analog LCL768 induces mitophagy and metabolic stress in HNSCC. Resipher was used to measure real-time OCR over 24 hours to assess the impact of mitophagy on mitochondrial respiration.

View it here >>> aacrjournals.org/cancerres/ar...

Lucid Scientific @lucidscientific.bsky.social · 8d

Our busy fall event season continues on with next week's Cancer Metabolism Congress in France! Mike Lu will be representing Lucid, with a range of topics including host metabolic reprogamming. Stop by our booth and learn more about our Resipher technology.

Event info >>> www.metabolism-cancer.com

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Lucid Scientific @lucidscientific.bsky.social · 12d

This study explores the physiological & metabolic consequences of whole-genome duplication using tetraploid C. elegans, organisms with four sets of chromosomes. Using Resipher, the team found that tetraploid worms displayed altered mitochondrial respiration profiles.

www.nature.com/articles/s41...

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Lucid Scientific @lucidscientific.bsky.social · 14d

Science is hard. Resipher is easy.

With the #Resipher starter kit, you'll be ready to track long-term, real-time oxygen consumption rate (OCR) data in just minutes - opening up a world of new possibilities within your research. Learn more here >>> lucidsci.com/resipher

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Lucid Scientific @lucidscientific.bsky.social · 20d

In this 4th edition of "Resipher in Action", we explore a research example that supports the role the technology can play in neurodegeneration and mitochondrial rescue.

View the paper here and learn how Resipher was used to provide direct supporting evidence >>> researchsquare.com/article/rs-6...

Lucid Scientific @lucidscientific.bsky.social · 22d

With Resipher and the new Timeprint Chart feature by Lucid Lab, track bioenergetic responses CONTINUOUSLY. Normalize to long-term pre-treatment baseline and capture the full picture of mitochondrial function.

View our Bioenergetic Profiling Guide to learn more >>> www.lucidsci.com/resources#do...

Lucid Scientific @lucidscientific.bsky.social · 27d

We're pleased to exhibit at next week's event organized by the Pathophysiology and Genetics of Neuron and Muscle, located in Lyon, France. We'll explore the latest research insights on tissue repair in health and disease.

Stop and say hi to Mike at the Lucid booth!

Event info >>> lnkd.in/er3np4gw

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Lucid Scientific @lucidscientific.bsky.social · Sep 8

In this edition of "Resipher in Action", we explore the role the technology can play in cancer metabolism and therapeutic discovery.

Using Resipher, the team achieved real-time, non-destructive oxygen consumption measurements in intact neurospheres.

Publication >> sciencedirect.com/science/arti...

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Lucid Scientific @lucidscientific.bsky.social · Sep 2

Introducing our new Timeprint Chart feature: a tool that provides deeper insight into your long-term oxygen consumption experiments, with the ability to analyze time-series inhibitor responses for bioenergetic profiling, therapeutic responses, or rescue assays (and much more).

Reach out for info!

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Lucid Scientific @lucidscientific.bsky.social · Aug 28

Gearing up for another event in Germany in less than two weeks: the 48th ELC meeting in Tutzing. We're honored to be a contributing sponsor!

If you're planning on attending or will be in the area, stop by the Lucid Scientific booth and say hi to our very own Mike Lu.

Event link >>> eas-elc.org

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Lucid Scientific @lucidscientific.bsky.social · Aug 26

Triolo and Khacho establish a protocol using the Resipher platform to measure mitochondrial oxygen consumption in live muscle stem cells and myoblasts over time.

Schedule your free Resipher demo >>> lnkd.in/ehMwTt5N

View the full publication here >>> lnkd.in/ePzAjHgF

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Lucid Scientific @lucidscientific.bsky.social · Aug 22

Using Resipher for live, label-free metabolic analysis, the study confirmed enhanced mitochondrial capacity in these organoids, which recapitulated disease phenotypes including arrhythmia and fibrosis, and enabled successful drug screening for desmoplakin cardiomyopathy.

nature.com/articles/s44...

Lucid Scientific @lucidscientific.bsky.social · Aug 19

Tan et al. show that pericellular oxygen can become limiting in standard culture due to media depth, creating hypoxia‑like effects even in low‑density cultures. Resipher measurements uncovered steep oxygen gradients driven by media volume & other key findings.

pubmed.ncbi.nlm.nih.gov/38580776/

Lucid Scientific @lucidscientific.bsky.social · Aug 15

Ryan Titmas will be at the Lucid booth at next week's Adipose Biology Conference in Montreal, as scientists from around the world come together to propel groundbreaking advancements in mechanisms of adipose tissue biology.

Stop by our booth if you're attending! Show info here >>> adiposebiology.com

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Lucid Scientific @lucidscientific.bsky.social · Aug 13

We're excited to be exhibitors and sponsors at this year's European Biological Rhythms Socity (EBRS) Congress! Mike Lu will be at our booth, ready to discuss our Resipher technology and the latest in chronobiology and sleep science.

Make plans to stop by our booth to learn more!

bit.ly/4mx2e7y

Lucid Scientific @lucidscientific.bsky.social · Aug 8

The publication demonstrates how Resipher enables sensitive measurement of OCR in C. elegans. The study provides detailed protocols for assessing mitochondrial function in live nematodes and highlights how variables critically impact OCR data interpretation.

sciencedirect.com/science/arti...

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Lucid Scientific @lucidscientific.bsky.social · Aug 5

The FDA's recognition of the need for more predictive human cell models in preclinical testing provides credence to advances in the ability to generate, monitor and quality control human preclinical models of disease.

Learn more about the power of OCR and how Resipher can help >>> lucidsci.com/ocr

Lucid Scientific @lucidscientific.bsky.social · Aug 1

The Resipher platform was used to continuously measure OCR and evaluate whether lactate can serve as an oxidative fuel in glioma cells. The team found that neither mouse nor human cells could sustain viability or ATP production when glucose was replaced with lactate.

biorxiv.org/content/10.1...

Lucid Scientific @lucidscientific.bsky.social · Jul 29

Turn your 32- or 96-well plate into a dynamic, real-time oxygen consumption reader - in just minutes!

This short video describes the simple setup process involved with the 32-channel version of the Resipher. For more information or to request a free trial, click here >>> lucidsci.com/resipher

Lucid Scientific @lucidscientific.bsky.social · Jul 25

New insight into how mitochondrial metabolism drives the pro-inflammatory secretory phenotype (SASP) in oncogene-induced senescent (OIS) fibroblasts - using long-term, real-time oxygen consumption tracking with the Resipher system.

Read the publication here >>> www.sciencedirect.com/science/arti...

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Lucid Scientific @lucidscientific.bsky.social · Jul 22

Excited for next week's AAIC show in Toronto! Lucid Global VP of Sales Ryan Titmas and Director of Customer Success Kin Lo will be set up at booth #1719 to exhibit our Resipher technology. Make plans to stop by if you're attending or in the area.

Show info here >>> aaic.alz.org

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Lucid Scientific @lucidscientific.bsky.social · Jul 17

Mitochondrial impairment is a universal cause and/or consequence of cellular dysfunction. Resipher's ability to track mitochondrial respiration allows for the standardization of impairment & function levels that initiate and/or maintain disease pathologies.

Schedule a demo! >>> lucidsci.com

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Lucid Scientific @lucidscientific.bsky.social · Jul 14

Researchers exhibit how 4-HMA and 4-HB can modify the course of mitochondrial encephalopathy driven by HPDL variants.

Catalina Vasilescu, PhD @cvasilescu.bsky.social · Jul 13

A superb #MitochondrialDisease selection of papers from #week28 !
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social

Shi et al, Coenzyme Q headgroup intermediates can ameliorate a mitochondrial encephalopathy
www.nature.com/articles/s41...

Coenzyme Q headgroup intermediates can ameliorate a mitochondrial encephalopathy - Nature

Decreased brain coenzyme Q10 levels cause encephalopathy and are associated with neurodegeneration; supplementation with 4-HMA or 4-HB restores coenzyme Q10 synthesis in mice and humans with HPDL vari...

www.nature.com

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Lucid Scientific @lucidscientific.bsky.social · Jul 10

Turn your incubator into a data powerhouse!

Resipher is the first truly non-invasive oxygen consumption rate (OCR) mointoring system - capable of tracking OCR and other data over extended periods for invaluable insights into cellular metabolism.

Learn more >>> lucidsci.com/resipher