Ludvig Daae Bjørndal
@ludvigdb.bsky.social
970 followers 460 following 73 posts
Clinical psychologist, PhD. Interested in mental health, environmental adversity, and their causes. http://www.ludvigbjorndal.com PROMENTA Research Center, University of Oslo PsychGen, Lovisenberg Diaconal Hospital / Norwegian Institute of Public Health
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Reposted by Ludvig Daae Bjørndal
tarjeiw.bsky.social
I had the pleasure of publishing an introduction to instrumental variables co-authored with Henrik Daae Zachrisson for the #JClinEpi key concepts in clinical epidemiology series! 🔬📖

www.jclinepi.com/article/S089...
ludvigdb.bsky.social
5/6. This paper follows several articles in which we show how risk factors exhibit granular associations with mental disorder symptoms. Such relationships can be overlooked when global measures, such as (symptom) sum scores, are used.

See also:
doi.org/10.1016/j.ja...
doi.org/10.1037/amp0...
ludvigdb.bsky.social
4/6. We describe three key findings:

1️⃣ Several symptom-specific associations were discernible.
2️⃣ Depressive symptoms were more strongly tied to financial adversity compared with anxiety.
3️⃣ Hopelessness about the future was most strongly connected to financial adversity.
ludvigdb.bsky.social
3/6. We incorporate multiple subjectively assessed financial factors (e.g., ability to cope with unforeseen expenses) and register-based financial data (e.g., income, assets).
ludvigdb.bsky.social
2/6. We apply a systems-based approach to identify symptom-specific relationships. Why? Financial adversity is complex and multidimensional and may exhibit granular associations with specific mental disorder symptoms (i.e., different mental health experiences).
ludvigdb.bsky.social
New paper! 📜 In nearly 50,000 individuals randomly sampled from the general population, we apply a symptom-specific perspective to examine which anxiety and depressive symptoms are most strongly associated with various aspects of financial adversity

doi.org/10.1016/j.ss...
Reposted by Ludvig Daae Bjørndal
lakens.bsky.social
An abbreviation (ABB) in a journal article (JA) or Grant Application (GA) is rarely worth the words it saves. Every ABB requires cognitive resources (CR) and at my age by the time I'm halfway through a JA or GA I no longer have the CR to remember what your ABB stood for.
Reposted by Ludvig Daae Bjørndal
jamanetworkopen.com
Childhood bereavement was associated with an increased risk of psychiatric disorders in adulthood, partly due to changes in stress resilience measured in late adolescence. https://ja.ma/44jTkEo
Stress Resilience and Risk of Psychiatric Disorders After Childhood Bereavement
Reposted by Ludvig Daae Bjørndal
ludvigdb.bsky.social
(9/9) This work was conducted as part of my research visit at Karolinska Institutet last year. Many thanks to all of the fantastic collaborators on this paper!
ludvigdb.bsky.social
(8/9) Still, our findings suggest that altered stress resilience is one mechanism linking childhood loss of a parent or sibling to psychiatric disorder risk in adulthood.

This is among the most comprehensive longitudinal studies on childhood bereavement and mental health across decades of life.
ludvigdb.bsky.social
(7/9) There are some important limitations: We lack information about the resilience measure and only one measurement was available. Generalisability is also uncertain, with strong assumptions underlying causal mediation analysis, pointing to the need for triangulation across methods.
ludvigdb.bsky.social
(6/9) Using causal mediation analysis (see vanderWeele 2014), we identified a mediating effect of stress resilience on the associations between childhood bereavement and psychiatric disorder risk.

The proportion mediated ranged from 6–22%, depending on the model and outcome.
ludvigdb.bsky.social
(5/9) We found that loss of a parent/sibling, in particular parental loss, is associated with increased risk of psychiatric disorders in adulthood. The strongest associations were with depression.

Bereavement was also linked to a higher probability of lower stress resilience in late adolescence.
ludvigdb.bsky.social
(4/9) We used Swedish registry data from more than 1.7 million individuals, with a follow-up of up to 34 years. Resilience was measured around age 18.

This unique dataset allowed for conducting comprehensive longitudinal and mediation analyses, with strong multivariable adjustment.
ludvigdb.bsky.social
(3/9) And few studies have examined the potential mechanistic role of resilience in associations between childhood bereavement and psychiatric disorder risk.

We ask: Does altered stress resilience mediate associations between bereavement experiences in childhood and psychiatric disorder risk?
ludvigdb.bsky.social
(2/9) Associations between childhood bereavement and increased risk of depression have been documented for > 60 years.

However, most studies have short follow-up durations (e.g., first two years after bereavement) and not comprehensively examined associations with different psychiatric outcomes.
ludvigdb.bsky.social
📢 Super excited to share this work: We examine how childhood bereavement is linked to an increased risk of psychiatric disorders, and identify altered stress resilience as a mediating mechanism, using data from 1.7 million individuals followed for up to 34 years (!)

jamanetwork.com/journals/jam...
Stress Resilience and Risk of Psychiatric Disorders After Childhood Bereavement
This cohort study evaluates whether stress resilience mediates the association between childhood bereavement and psychiatric disorder risk in adulthood.
jamanetwork.com
ludvigdb.bsky.social
New paper! 📜

Most of my work relies on large cohort datasets. But how can we ensure transparency and robust research findings using such data?

Here, we present a case study of reproducible practices in epi (with MoBa) and a practical example showing how these practices can be applied.
ludvigdb.bsky.social
Hvordan har du det? Vi samler inn data fra hele verden gjennom en kort spørreundersøkelse (3–4 min). Vi ser på hvordan folk har det – psykisk, sosialt og økonomisk – og hva de tror om fremtiden ett år fra nå. Delta gjerne via denne lenken (English available):

cumc.co1.qualtrics.com/jfe/form/SV_...
Spørreundersøkelse om mental helse
En kort spørreundersøkelse om mental helse for alle, hvor som helst (vel, for alle over 18...)
cumc.co1.qualtrics.com
ludvigdb.bsky.social
4/4. The paper has many interesting points on multicomponent positive psychology interventions, scalable interventions, and mechanisms of change.

Thank you also to Behaviour Research and Therapy for a really great peer-review process, which helped strengthen this work.